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公开(公告)号：US20120190613A1
公开(公告)日：2012-07-26
申请号：US13392152
申请日：2010-08-26
摘要： The invention features echinocandin class compounds that have been modified to (i) have activity against one or more fungal species or genera; (ii) have increased aqueous solubility; (iii) have an increased therapeutic index; (iv) be suitable for topical administration; and/or (v) be suitable for oral administration. The echinocandin class compounds of the invention include, for example, a PEG, alkyl-PEG, aryl-PEG, alkaryl-PEG, PEG-alkyl, PEG-aryl, or PEG-alkaryl substituent.
摘要翻译： 本发明具有经修饰以（i）具有针对一种或多种真菌种或属的活性的棘白菌素类化合物; （ii）增加水溶性; （iii）治疗指数增加; （iv）适合局部给药; 和/或（v）适于口服给药。 本发明的棘白菌素类化合物包括例如PEG，烷基-PEG，芳基-PEG，烷芳基-PEG，PEG-烷基，PEG-芳基或PEG-烷芳基取代基。
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公开(公告)号：US20060040221A1
公开(公告)日：2006-02-23
申请号：US10920621
申请日：2004-08-18
申请人： Robert Dickerson , Kenneth Duke , Fred Kelley
发明人： Robert Dickerson , Kenneth Duke , Fred Kelley
IPC分类号： G03C1/00
CPC分类号： G03C1/49863 , G03C1/0051 , G03C1/498 , G03C1/49818 , G03C1/49827 , G03C1/49845 , G03C1/815 , G03C1/8155 , G03C5/17 , G03C2001/03594 , G03C2001/7425 , G03C2005/3007
摘要： Photothermographic materials are coated with thermally developable imaging layers on both sides of the support. Such materials can be arranged in association with one or more phosphor intensifying screens capable of providing emission at a predetermined wavelength in imaging assemblies. These imaging assemblies can be exposed to X-radiation and thereby form a latent image in the photothermographic material that can be heat developed and used for medical diagnosis. The support of the photothermographic materials contains a crossover control composition that absorbs radiation at the predetermined wavelength, for example within the range of 300 to 450 nm, and has limited absorption at higher wavelengths.
摘要翻译： 光热照相材料在支撑体的两侧涂覆有热显影成像层。 这样的材料可以与能够在成像组件中以预定波长提供发射的一个或多个荧光增强屏相关联地布置。 这些成像组件可以暴露于X射线，从而在光热照相材料中形成可以被热显影并用于医学诊断的潜像。 光热敏成像材料的支持物包含一种交叉控制组合物，其吸收预定波长的辐射，例如在300至450nm的范围内，并且在较高波长处具有有限的吸收。
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公开(公告)号：US20060216658A1
公开(公告)日：2006-09-28
申请号：US11091049
申请日：2005-03-28
申请人： Alan Fitterman , Robert Dickerson , Kenneth Duke
发明人： Alan Fitterman , Robert Dickerson , Kenneth Duke
IPC分类号： G03C5/26
摘要： Photographic silver halide materials containing an incorporated black-and-white developing agent can be quickly and simply processed using unique processing compositions and methods. In a “two-step” method, the exposed material is contacted with an alkaline activator solution followed by a fixing composition. In a “one-step” method, activation and fixing are combined using a single alkaline activator-fixing composition containing the fixing agent. None of the processing solutions include black-and-white developing agents. The photographic silver halide materials are preferably radiographic silver halide materials that have a reflective support and provide black-and-white images that can be viewed without a light box.
摘要翻译： 含有并入的黑白显影剂的摄影卤化银材料可以使用独特的加工组合物和方法快速且简单地加工。 在“两步”方法中，暴露的材料与碱性活化剂溶液接触，然后与定影组合物接触。 在“一步”方法中，使用含有固定剂的单一碱性活化剂固定组合物来组合活化和固定。 处理方法都不包括黑白显影剂。 照相卤化银材料优选是具有反射支持并且提供可以在没有灯箱的情况下被观察的黑白图像的射线照相卤化银材料。
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公开(公告)号：USD341380S
公开(公告)日：1993-11-16
申请号：US817130
申请日：1991-12-31
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