公开(公告)号：US20070098636A1

公开(公告)日：2007-05-03

申请号：US10578811

申请日：2004-11-04

申请人： John Wagner ,  Utpal Pajvani ,  John Wagner

发明人： John Wagner ,  Utpal Pajvani ,  John Wagner

IPC分类号： A61K49/00

CPC分类号： G01N33/6893 ,  A61K49/0004 ,  G01N33/74 ,  G01N2333/72 ,  G01N2800/042 ,  G01N2800/52

摘要： A patient who is a responder to a therapeutic treatment for insulin resistance or for one or more diseases associated with type 2 diabetes can be identified by the method of measuring the amount of HMW adiponectin and the amount of total adiponectin or LMW adiponectin in the patient's tissue (usually plasma or serum) before the therapeutic treatment commences; then commencing the therapeutic treatment; and finally measuring the amount of HMW adiponectin and the amount of either total adiponectin or LMW adiponectin in the patient's plasma or serum one or more times after commencement of the therapeutic treatment. The patient is predicted to be a responder to the therapeutic treatment if the ratio of the amount of HMW adiponectin to the amount of total adiponectin or LMW adiponectin increases after the therapeutic treatment commences.

摘要翻译： 作为对胰岛素抵抗或与2型糖尿病相关的一种或多种疾病的治疗性治疗的反应者的患者可以通过测量患者组织中HMW脂连蛋白的量和总脂连蛋白或LMW脂联素的量的方法来鉴定 （通常为血浆或血清）; 然后开始治疗; 最后在治疗开始后测定HMW脂联素的量和患者血浆或血清中一次或多次的总脂联素或LMW脂联素的量。 如果在治疗开始后HMW脂联素的量与总脂连蛋白或LMW脂联素的量的比例增加，则患者被预测为治疗性应答者。

公开(公告)号：US08991607B2

公开(公告)日：2015-03-31

申请号：US13634814

申请日：2011-03-18

申请人： John Wagner ,  Flemming Wagner

发明人： John Wagner ,  Flemming Wagner

IPC分类号： B65D83/04 ,  B65D75/32 ,  A61J1/03 ,  B65D81/05 ,  B65D81/38

CPC分类号： A61J1/035 ,  A61J1/03 ,  B65B43/40 ,  B65D75/327 ,  B65D75/367 ,  B65D75/527 ,  B65D81/05 ,  B65D81/3816 ,  B65D83/0463 ,  B65D2575/3245 ,  B65D2585/56

摘要： The invention relates to a system for opening a medical blister package which is easy and convenient to open for people of all level of ability and dexterity. Its design allows for selective access to the blisters by following a predetermined opening sequence, therefore minimizing involuntary wrong up taking of medicine due to patient errors as wrong sequential opening is not achievable by involuntary mistakes.

摘要翻译： 本发明涉及一种用于打开医疗泡罩包装的系统，其容易且方便地为具有各种能力和灵巧性的人开放。 其设计允许通过遵循预定的打开顺序来选择性地进入水疱，因此由于患者错误而导致由于错误的顺序打开引起的不必要的错误服药不能由非自愿的错误实现。

公开(公告)号：US08720251B2

公开(公告)日：2014-05-13

申请号：US13206882

申请日：2011-08-10

申请人： Geoffrey Stephen Henshaw ,  John Wagner ,  Simon Naisbitt ,  Bryon Wright

发明人： Geoffrey Stephen Henshaw ,  John Wagner ,  Simon Naisbitt ,  Bryon Wright

IPC分类号： G01N27/02

CPC分类号： G01N27/124 ,  G01N33/0037 ,  G01N33/0059 ,  Y02A50/245

摘要： A gas detection system comprising a gas sensor having a detection surface for detecting an analyte gas, the accuracy of detection being degraded by the presence of an unwanted gas at the sensor, and a thermal scrubber layer directly adjacent said detection surface of the gas sensor defining a diffusion path for the analyte and unwanted gases to traverse through to the detection surface, the diffusion path having a sufficient length and the thermal scrubber being heated by the heater to a sufficient temperature capable of at least partially thermally decomposing the unwanted gas prior to contacting the detection surface to thereby improve the accuracy of the sensor. The system further comprises a heater that is preferably arranged to heat both the detection surface and the thermal scrubber. The invention is particularly useful for improving the performance of an NO2 gas sensor in the presence of ozone (O3).

摘要翻译： 一种气体检测系统，包括具有用于检测分析物气体的检测表面的气体传感器，通过在传感器处存在不需要的气体而降低检测精度，以及直接邻近所述气体传感器的检测表面定义的热洗涤器层 用于分析物和不需要的气体穿过检测表面的扩散路径，扩散路径具有足够的长度，并且热洗涤器被加热器加热至能够在接触之前至少部分地热分解不想要的气体的足够温度 检测表面，从而提高传感器的精度。 该系统还包括加热器，其优选地布置成加热检测表面和热洗涤器两者。 本发明特别可用于在存在臭氧（O 3）的情况下改善NO 2气体传感器的性能。

公开(公告)号：US08459458B2

公开(公告)日：2013-06-11

申请号：US13634822

申请日：2011-03-18

申请人： John Wagner ,  Flemming Wagner

发明人： John Wagner ,  Flemming Wagner

IPC分类号： B65D83/04

CPC分类号： A61J1/035 ,  A61J1/03 ,  B65B43/40 ,  B65D75/327 ,  B65D75/367 ,  B65D75/527 ,  B65D81/05 ,  B65D81/3816 ,  B65D83/0463 ,  B65D2575/3245 ,  B65D2585/56

摘要： A disposable rigid package containing pharmaceutical compositions which protects tablets, capsules, soft shell pills against hard transporting conditions and undesired rupture. The package allows for personal transportation, e.g. in a pocket, and it is easy and convenient to open for people of all level of ability and dexterity. Its design allows for transport as standard mail withstanding temperature fluctuation, vibrations and shocks, mechanical pressure and variation in atmospheric pressure which may occur during transport.

摘要翻译： 一种包含药物组合物的一次性刚性包装，其保护片剂，胶囊，软壳丸剂抵抗硬运输条件和不期望的破裂。 包装允许个人运输，例如 在口袋里，为各种能力和灵巧的人开放是容易和方便的。 其设计允许作为标准邮件承受温度波动，振动和冲击，机械压力和运输过程中可能发生的大气压力变化的运输。

公开(公告)号：US07584784B2

公开(公告)日：2009-09-08

申请号：US11760935

申请日：2007-06-11

申请人： John Wagner

发明人： John Wagner

IPC分类号： E21B43/00

CPC分类号： E21B43/127 ,  F04B9/105 ,  F04B47/02 ,  F04B47/04

摘要： A reciprocating drive apparatus for connection to a top end of a rod swing to drive a downhole pump located in a well includes a plate adapted to be fastened to a top end of a well head assembly of the well, and a mast attachable to the plate in a substantially vertical working position. A hydraulic cylinder is attached to the mast such that when the mast is in the working position the hydraulic cylinder is oriented substantially vertically, and such that the hydraulic cylinder can extend and retract in response to a controller. A tether is adapted to be fixed to the well head and to the top end of the rod string and is configured such that the hydraulic cylinder engages the tether to move the rod string up and down as the hydraulic cylinder extends and retracts.

摘要翻译： 用于连接到杆摆动的顶端以驱动位于井中的井下泵的往复运动装置包括适于紧固到井的井头组件的顶端的板，以及可附接到板的杆 在基本垂直的工作位置。 液压缸连接到桅杆，使得当桅杆处于工作位置时，液压缸基本垂直地定向，并且使得液压缸响应于控制器而伸缩。 系绳适于固定到井口和杆串的顶端，并且构造成使得液压缸接合系绳，以随着液压缸的延伸和缩回而使杆串上下移动。

公开(公告)号：US20080099211A1

公开(公告)日：2008-05-01

申请号：US11760935

申请日：2007-06-11

申请人： John Wagner

发明人： John Wagner

IPC分类号： E21B19/02

CPC分类号： E21B43/127 ,  F04B9/105 ,  F04B47/02 ,  F04B47/04

摘要： A reciprocating drive apparatus for connection to a top end of a rod swing to drive a downhole pump located in a well includes a plate adapted to be fastened to a top end of a well head assembly of the well, and a mast attachable to the plate in a substantially vertical working position. A hydraulic cylinder is attached to the mast such that when the mast is in the working position the hydraulic cylinder is oriented substantially vertically, and such that the hydraulic cylinder can extend and retract in response to a controller. A tether is adapted to be fixed to the well head and to the top end of the rod string and is configured such that the hydraulic cylinder engages the tether to move the rod string up and down as the hydraulic cylinder extends and retracts.

摘要翻译： 用于连接到杆摆动的顶端以驱动位于井中的井下泵的往复运动装置包括适于紧固到井的井头组件的顶端的板，以及可附接到板的杆 在基本垂直的工作位置。 液压缸连接到桅杆，使得当桅杆处于工作位置时，液压缸基本垂直地定向，并且使得液压缸响应于控制器而伸缩。 系绳适于固定到井口和杆串的顶端，并且构造成使得液压缸接合系绳，以随着液压缸的延伸和缩回而使杆串上下移动。

公开(公告)号：US20070028225A1

公开(公告)日：2007-02-01

申请号：US11528982

申请日：2006-09-27

申请人： James Whittaker ,  Rahul Chaturvedi ,  John Wagner

发明人： James Whittaker ,  Rahul Chaturvedi ,  John Wagner

IPC分类号： G06F9/44

CPC分类号： G06F11/3612 ,  G06F21/53 ,  G06F2221/2141 ,  G06F2221/2149

摘要： A method of executing a program in a controlled environment includes initiating execution of an operating system with which the program is adapted to execute, inserting redirection logic at the beginning of the program, and executing the program such that the redirection logic is executed. A current instruction pointer is stored, and execution control is redirected to a program loader. The program loader selects a first block of instructions of the program, based at least in part on the stored current instruction pointer. This selected block of instructions is manipulated to provide a first phantom instruction block, which is executed in the controlled environment. This manipulation includes copying at least a portion of the selected first block to form the first phantom instruction block.

公开(公告)号：US20060290576A1

公开(公告)日：2006-12-28

申请号：US11068217

申请日：2005-03-01

申请人： John Wagner ,  Alison Wagner

发明人： John Wagner ,  Alison Wagner

IPC分类号： H01Q1/24

CPC分类号： H01Q1/44 ,  H01Q1/242

摘要： Antenna identifier and decorative item to be used for any electronic device that has an exterior antenna.

摘要翻译： 用于具有外部天线的任何电子设备的天线标识符和装饰物品。

公开(公告)号：US20060130016A1

公开(公告)日：2006-06-15

申请号：US11286274

申请日：2005-11-23

申请人： John Wagner

发明人： John Wagner

IPC分类号： G06F9/45

CPC分类号： G06F9/4812 ,  G06F9/54 ,  G06F2209/481 ,  G06F2209/542

摘要： A process of kernel-mode instruction interception on a host CPU includes copying CPU-executed instructions to respective new locations in memory, and transferring CPU control to the copied instructions for execution.

摘要翻译： 主机CPU上的内核模式指令截取过程包括将CPU执行的指令复制到存储器中的各个新位置，并将CPU控制转移到复制的指令执行。

公开(公告)号：US20050251794A1

公开(公告)日：2005-11-10

申请号：US11098025

申请日：2005-03-30

申请人： Jason Taylor ,  John Wagner ,  Matthew Taylor

发明人： Jason Taylor ,  John Wagner ,  Matthew Taylor

IPC分类号： G06F9/45

CPC分类号： G06F11/3664 ,  G06F11/362

摘要： A process of debugging application code includes stopping execution of the application, stepping backward through the code by line or instruction, stopping at a bug point in the code, modifying the state of the application at the bug point, and resuming execution of the application. A memory medium stores instructions executable by a processor to perform the process, or stores instructions executable by a processor to provide an interface that allows a user to perform the process. A system includes a processor that executes instructions to perform the process, or includes a processor that executes instructions to provide an interface that allows a user to perform the process.

摘要翻译： 调试应用程序代码的过程包括停止应用程序的执行，逐行退出逐行或指令，停止代码中的错误点，在错误点修改应用程序的状态，并恢复应用程序的执行。 存储介质存储由处理器执行以执行处理的指令，或存储可由处理器执行的指令，以提供允许用户执行处理的接口。 系统包括执行执行该过程的指令的处理器，或包括执行指令以提供允许用户执行该过程的接口的处理器。