公开(公告)号：US06242598B1

公开(公告)日：2001-06-05

申请号：US09532222

申请日：2000-03-22

Applicant: Tyler Arthur Stevenson ,  Michael Ackerman ,  Pascal Hayoz ,  Roger Meuwly ,  John Francis Oswald ,  Christian Schregenberger

Inventor： Tyler Arthur Stevenson ,  Michael Ackerman ,  Pascal Hayoz ,  Roger Meuwly ,  John Francis Oswald ,  Christian Schregenberger

IPC: C07D25122

CPC classification number: C07D251/24

Abstract: A process for preparing 2-(2,4-dihydroxyphenyl)-4.6-diaryl-s-triazines in three steps starting with cyanuric chloride is described. Step 1 involves the nucleophilic (basic) displacement of one chlorine atom with a phenolic moiety. Step 2 involves a Friedel-Crafts reaction using a Lewis acid catalyst (preferably aluminum chloride) to replace the remaining two chlorine atoms with aryl groups such as xylyl. Finally, step 3 involves replacing the phenolic moiety with resorcinol using either a Lewis acid or protic acid catalyst or combinations thereof. Some additional processes only peripherally related to the three-step process outlined above are also described for the preparation of various s-triazine compounds. The s-triazines prepared are useful as UV absorbers for the stabilization of organic substrates against the adverse effects of actinic light.

Abstract translation: 描述了从氰尿酰氯开始三步制备2-（2,4-二羟基苯基）-4,6-二芳基-s-三嗪的方法。 步骤1涉及一个氯原子与酚部分的亲核（碱性）置换。 步骤2涉及使用路易斯酸催化剂（优选氯化铝）的Friedel-Crafts反应以用诸如二甲苯基之类的芳基取代剩余的两个氯原子。 最后，步骤3涉及使用路易斯酸或质子酸催化剂或其组合将间苯二酚替代酚部分。 还描述了与上述三步法相关的一些附加方法，用于制备各种s-三嗪化合物。 制备的s-三嗪可用作稳定有机基材以防止光化性光的不利影响的紫外线吸收剂。