公开(公告)号：US20060148800A1

公开(公告)日：2006-07-06

申请号：US11206703

申请日：2005-08-17

Applicant: Heinz Stadtmueller ,  Harald Engelhardt ,  Martin Steegmaier ,  Anke Baum ,  Ulrich Guertler ,  Andreas Schoop ,  Jen Quant ,  Flavio Solca ,  Rudolf Hauptmann ,  Ulrich Reiser ,  Stephan Zahn ,  Lars Herfurth

Inventor： Heinz Stadtmueller ,  Harald Engelhardt ,  Martin Steegmaier ,  Anke Baum ,  Ulrich Guertler ,  Andreas Schoop ,  Jen Quant ,  Flavio Solca ,  Rudolf Hauptmann ,  Ulrich Reiser ,  Stephan Zahn ,  Lars Herfurth

IPC: A61K31/53

CPC classification number: C07D239/42 ,  C07D239/48 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D413/12 ,  C07D413/14 ,  C07D453/02 ,  C07D471/04 ,  C07D487/04 ,  C07D487/08 ,  C07D491/08 ,  C07D491/10

Abstract: The present invention encompasses compounds of general formula (1), wherein A, W, X, Y, Z, Ra, Rb, Rc, R1 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.