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公开(公告)号：US09138920B2
公开(公告)日：2015-09-22
申请号：US12446603
申请日：2007-10-17
Abstract: A method and apparatus for forming hard shell capsule components, wherein the capsule components are formed from a material which undergoes gelation upon heating, such as HPMC. A heat station is provided to heat a plurality of molds prior to dipping into a solution of the thermogeling material. The drying conditions following dipping are carefully controlled to control the rate of drying.
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公开(公告)号：US08715722B2
公开(公告)日：2014-05-06
申请号：US12991950
申请日：2009-05-07
Applicant: Hilde Buydts , Jan Donaat Sinnaeve , Stefaan Jaak Vanquickenborne
Inventor： Hilde Buydts , Jan Donaat Sinnaeve , Stefaan Jaak Vanquickenborne
IPC: A61K9/48
CPC classification number: A61J3/072
Abstract: The invention relates to a capsule comprising a hollow tubular body (2), a hollow cap (3) telescopically engageable on the body (2), the body (2) and the cap (3) defining an inner volume therebetween and being provided with complementary snap-fit means (12, 21) for locking the cap (3) on the body (2) in the fully closed final position, the complementary snap-fit means (12, 21) comprising a locking ring (12) formed on the body (2) and a complementary ridge member (21) formed on the cap (3), at least one air-vent (14) formed as an axial recess on the outer surface of the body (2) and suitable for ensuring fluid communication between the inner volume and the atmosphere. The capsule (1) is configured such that, in the fully closed final position, the inner surface of the cap (3) fits on the outer surface of the body (2) over a continuous circumferential contact section (33) and the air-vent (14) axially extends from the open end (5) of the body (2) toward the contact section (33), so as to provide fluid communication between the inner volume and the atmosphere over the whole range of engagement positions, excluding the fully closed final position wherein the inner surface of the cap (3) sealingly engages the outer surface of the body (2) over the contact section (33). Application to capsules for liquid dosages.
Abstract translation: 本发明涉及一种胶囊，其包括中空管状体（2），可伸缩地接合在主体（2）上的空心帽（3），主体（2）和帽（3）在其间限定内部容积， 用于在完全闭合的最终位置中将盖（3）锁定在主体（2）上的互补卡扣配合装置（12,21），所述互补卡扣配合装置（12,21）包括形成在 所述主体（2）和形成在所述盖（3）上的互补脊部件（21），至少一个形成为所述主体（2）的外表面上的轴向凹部的排气口（14），并且适于确保流体 内容与气氛之间的沟通。 胶囊（1）构造成使得在完全闭合的最终位置中，盖（3）的内表面在连续的圆周接触部分（33）上装配在主体（2）的外表面上， 排气口（14）从主体（2）的开口端（5）朝向接触部分（33）轴向延伸，以便在整个接合位置范围内在内部容积和大气之间提供流体连通，不包括 完全闭合的最终位置，其中盖（3）的内表面在接触部分（33）上密封地接合主体（2）的外表面。 用于液体剂量的胶囊。
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公开(公告)号：US20110006457A1
公开(公告)日：2011-01-13
申请号：US12446603
申请日：2007-10-17
Abstract: A method and apparatus for forming hard shell capsule components, wherein the capsule components are formed from a material which undergoes gelation upon heating, such as HPMC. A heat station is provided to heat a plurality of molds prior to dipping into a solution of the thermogeling material. The drying conditions following dipping are carefully controlled to control the rate of drying.
Abstract translation: 一种用于形成硬壳胶囊组分的方法和装置，其中胶囊组分由加热时经历凝胶化的材料形成，例如HPMC。 提供加热站以在浸入热胶材料的溶液之前加热多个模具。 仔细控制浸渍后的干燥条件以控制干燥速率。
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公开(公告)号：US20110064802A1
公开(公告)日：2011-03-17
申请号：US12991950
申请日：2009-05-07
Applicant: Hilde Buydts , Jan Donaat Sinnaeve , Stefaan Jaak Vanquickenborne
Inventor： Hilde Buydts , Jan Donaat Sinnaeve , Stefaan Jaak Vanquickenborne
IPC: A61K9/48
CPC classification number: A61J3/072
Abstract: The invention relates to a capsule comprising a hollow tubular body (2), a hollow cap (3) telescopically engageable on the body (2), the body (2) and the cap (3) defining an inner volume therebetween and being provided with complementary snap-fit means (12, 21) for locking the cap (3) on the body (2) in the fully closed final position, the complementary snap-fit means (12, 21) comprising a locking ring (12) formed on the body (2) and a complementary ridge member (21) formed on the cap (3), at least one air-vent (14) formed as an axial recess on the outer surface of the body (2) and suitable for ensuring fluid communication between the inner volume and the atmosphere. The capsule (1) is configured such that, in the fully closed final position, the inner surface of the cap (3) fits on the outer surface of the body (2) over a continuous circumferential contact section (33) and the air-vent (14) axially extends from the open end (5) of the body (2) toward the contact section (33), so as to provide fluid communication between the inner volume and the atmosphere over the whole range of engagement positions, excluding the fully closed final position wherein the inner surface of the cap (3) sealingly engages the outer surface of the body (2) over the contact section (33). Application to capsules for liquid dosages.
Abstract translation: 本发明涉及一种胶囊，其包括中空管状体（2），可伸缩地接合在主体（2）上的空心帽（3），主体（2）和帽（3）在其间限定内部容积， 用于在完全闭合的最终位置中将盖（3）锁定在主体（2）上的互补卡扣配合装置（12,21），所述互补卡扣配合装置（12,21）包括形成在 所述主体（2）和形成在所述盖（3）上的互补脊部件（21），至少一个形成为所述主体（2）的外表面上的轴向凹部的排气口（14），并且适于确保流体 内容与气氛之间的沟通。 胶囊（1）构造成使得在完全闭合的最终位置中，盖（3）的内表面在连续的圆周接触部分（33）上装配在主体（2）的外表面上， 排气口（14）从主体（2）的开口端（5）朝向接触部分（33）轴向延伸，以便在整个接合位置范围内在内部容积和大气之间提供流体连通，不包括 完全闭合的最终位置，其中盖（3）的内表面在接触部分（33）上密封地接合主体（2）的外表面。 用于液体剂量的胶囊。
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