公开(公告)号：US5228455A

公开(公告)日：1993-07-20

申请号：US703222

申请日：1991-05-20

Applicant: James E. Barcel

Inventor： James E. Barcel

IPC: A61M25/01 ,  A61N1/05

CPC classification number: A61N1/05 ,  A61N1/056 ,  A61M25/0113 ,  A61M25/09041

Abstract: An implant tool for use with an endocardial or other implantable lead having an extendable/retractable positive fixation tip includes a hollow cylindrical housing and a custom designed stylet. The cylindrical housing attaches to a proximal end of the implantable lead. The stylet is inserted through the implant tool and into a lumen of the lead. The presence of the stylet, made from a length of relatively stiff wire, helps guide the distal tip of the lead to a desired implant location. The cylindrical housing includes a body portion and an end portion. The end portion is rotatable relative to the body portion. The stylet includes a knob on its proximal end, and also includes a stub pin slightly forward of its proximal end. The stub pin is received within a slot along the side of the cylindrical housing. Two spaced-apart recesses along the length of the slot allow the stub pin to be respectively held therein. When the stub pin is held in a first recess, the stylet wire has advanced sufficiently far into the lead to facilitate implantation of the lead, but retains the positive fixation tip in its retracted position. When the stub pin is locked in a second recess, the stylet wire has advanced sufficiently far into the lead to engage the positive fixation tip and move it to its extended position. A method of using the implant tool is also disclosed.

Abstract translation: 用于心内膜或其他可植入引线的植入工具具有可伸缩的正固定尖端，其包括中空的圆柱形外壳和定制设计的探针。 圆柱形壳体连接到可植入引线的近端。 探针插入植入工具并进入导管的内腔。 由长度相对刚硬的线制成的探针的存在有助于将导线的远端引导到期望的植入位置。 圆柱形壳体包括主体部分和端部部分。 端部可相对于主体部分旋转。 探针包括其近端的旋钮，并且还包括其近端稍微向前的短针。 短柱销被接纳在沿圆柱形壳体侧面的槽内。 沿着狭槽的长度的两个间隔开的凹槽允许短针分别保持在其中。 当短针被保持在第一凹槽中时，探针线已经进入到引线中足够远，以便于引线的注入，但是将正的固定末端保持在缩回位置。 当短针被锁定在第二凹槽中时，探针线已经进入足够远的引线以接合正的固定尖端并将其移动到其延伸位置。 还公开了使用植入工具的方法。

公开(公告)号：US5304219A

公开(公告)日：1994-04-19

申请号：US894395

申请日：1992-06-05

Applicant: Edward Chernoff ,  Harry W. Fletcher ,  Jeryle L. Walter ,  James E. Barcel

Inventor： Edward Chernoff ,  Harry W. Fletcher ,  Jeryle L. Walter ,  James E. Barcel

IPC: A61B5/145 ,  A61B5/1459 ,  A61N1/05 ,  A61N1/365 ,  A61N1/37 ,  H01R43/00

CPC classification number: A61N1/056 ,  A61N1/36557 ,  A61N1/3702 ,  Y10T29/49117

Abstract: An in-line, multipolar proximal connector assembly for an implantable stimulation lead is provided which incorporates at least one sensor. Advantageously, the present invention uses straight conductive rods, or wires, to electrically connect the proximal terminals to a multilumen lead body. The straight conductive rods enable the diameter of the lead assembly to remain small. Additional terminals can easily be added by simply decreasing the spacing between terminals and adding additional conductive rods. In one embodiment, insulating spacers are premolded to include protruding portions which interlock with the ring terminals. Recesses within the insulating spacers are dimensioned to self-position the ring terminals a precise distance from the pin terminal according to precise dimensions defined by the VS-1 (or other) standards. In another embodiment, the terminals are injection molded. While the present invention is directed towards a quadrapolar (four conductors) design, it may be easily adapted to a bipolar, tripolar or multipolar (five conductors or more) design.

Abstract translation: 提供了一种用于可植入刺激引线的在线多极近端连接器组件，其包括至少一个传感器。 有利地，本发明使用直的导电杆或电线将近端端子电连接到多腔体引线体。 直的导电棒使引线组件的直径保持较小。 通过简单地减小端子之间的间距并添加额外的导电棒，可以轻松添加附加端子。 在一个实施例中，绝缘间隔件被预成型以包括与环形端子互锁的突出部分。 绝缘间隔件内的凹槽的尺寸被设计成根据由VS-1（或其他）标准定义的精确尺寸，将环形端子自身定位成与端子的精确距离。 在另一个实施例中，端子被注射成型。 虽然本发明针对四极（四导体）设计，但是它可以容易地适应于双极性，三极性或多极（五导体或更多）设计。

公开(公告)号：US5014720A

公开(公告)日：1991-05-14

申请号：US461703

申请日：1990-01-08

Applicant: James E. Barcel ,  Thomas M. Soukup

Inventor： James E. Barcel ,  Thomas M. Soukup

IPC: A61N1/05

CPC classification number: A61N1/056

Abstract: A joint assembly which may be used for affixing a helically wound lead conductor coil to an electrode of a pacemaker. The electrode has a longitudinal bore and a coaxial counterbore. One end of the coil is fittingly attached to a reduced diameter end of a press tube. The outer diameter of the extreme outer surface of the coil on the press tube is slightly greater than the inner diameter of the counterbore in the electrode. The reduced diameter end of the press tube with the coil thereon is fittingly inserted into the counterbore. This results in a solid connection between the lead conductor coil and the electrode without causing any visible alteration of the outer surface of the electrode.

Abstract translation: 可用于将螺旋缠绕的引线导线线圈固定到起搏器的电极的接头组件。 电极具有纵向孔和同轴沉孔​​。 线圈的一端适配地连接到压力管的直径较小的端部。 压管上线圈的极外表面的外径略大于电极中沉孔的内径。 其上具有线圈的压力管的直径减小端被适当地插入沉孔中。 这导致引线导体线圈和电极之间的牢固连接，而不会引起电极的外表面的任何可见的改变。

公开(公告)号：US5275171A

公开(公告)日：1994-01-04

申请号：US562771

申请日：1990-08-06

Applicant: James E. Barcel

Inventor： James E. Barcel

IPC: A61N1/05 ,  A61N1/365

CPC classification number: A61N1/36557 ,  A61N1/056

Abstract: A physiological sensor forms an integral part of an implantable stimulation/sensing lead used with a medical device, such as a pacemaker. The stimulation/sensing lead includes a tip electrode to which a distal end of a first conductor is connected. The sensor is inserted in series with respective portions of a second conductor. A distal end of the second conductor/sensor is connected to the tip electrode. Operation of the stimulation/sensing lead occurs unipolarly through the first conductor only, with a signal return path being provided through the tip electrode and conductive body fluids. The sensor does not form part of the electrical circuit to the tip electrode, and there are no electrical connections or breaks in the insulation along the entire length of the first conductor. Electrical contact with the sensor is achieved during a time window when the stimulation/sensing lead is not being used by applying an appropriate operating signal, and measuring the resultant output signal, at the proximal ends of the first and second leads.

Abstract translation: 生理传感器构成与诸如起搏器的医疗装置一起使用的可植入刺激/感测引线的组成部分。 刺激/感测引线包括尖端电极，第一导体的远端连接到尖端电极。 传感器与第二导体的相应部分串联插入。 第二导体/传感器的远端连接到尖端电极。 刺激/感测引线的操作仅通过第一导体单向地发生，信号返回路径通过尖端电极和导电体液体提供。 传感器不形成电极至尖端电极的一部分，并且在第一导体的整个长度上绝缘体中没有电连接或断裂。 在通过在第一和第二引线的近端处施加合适的操作信号和测量所得到的输出信号来刺激/感测引线未被使用的时间窗口期间，实现与传感器的电接触。

公开(公告)号：US5267564A

公开(公告)日：1993-12-07

申请号：US716032

申请日：1991-06-14

Applicant: James E. Barcel ,  Alvin H. Weinberg ,  Shahram Moaddeb ,  James R. Thacker

Inventor： James E. Barcel ,  Alvin H. Weinberg ,  Shahram Moaddeb ,  James R. Thacker

IPC: A61B5/145 ,  A61B5/1459 ,  A61N1/05 ,  A61N1/365 ,  A61N1/37 ,  H01R43/00 ,  A61B5/0205

CPC classification number: A61N1/056 ,  A61N1/36557 ,  A61N1/3702 ,  Y10T29/49117

Abstract: The present invention includes a body implantable lead having a multi-polar proximal connector, at least a first conductor coupled to at least one stimulating electrode, a sensor for sensing at least one physiologic parameter of the body, and a second and a third conductor coupled to the sensor. The sensor is hermetically sealed in a D-shaped housing. Sensor components are mounted onto a microelectronic substrate which is advantageously placed on an inner flat portion of the D-shaped housing. End caps having glass frit sealing rings are used to seal the ends of the shell. A hermetic seal is easily achieved by heating the glass frit such that the glass frit reflows between the end caps and the shell. Advantageously, the sensor terminals are sized to fit snugly within a narrow bore of the end cap which is then welded closed. The D-shaped sensor is placed on a carrier having at least two lumens. At least the first and second conductors pass through the lumens for connection with the stimulating electrode and the distal end of the sensor. Advantageously, the D-shaped housing reduces the area that needs to be hermetically sealed by more than half, and thus reduces the overall diameter of the lead. Advantageously, the conductors coupled to the sensor function independently from the stimulation conductors so that interference with basic operation of the pacemaker is prevented.

公开(公告)号：US4815469A

公开(公告)日：1989-03-28

申请号：US166580

申请日：1988-03-10

Applicant: Donald M. Cohen ,  James E. Barcel ,  Michael D. Hooven

Inventor： Donald M. Cohen ,  James E. Barcel ,  Michael D. Hooven

IPC: A61B5/00 ,  A61N1/365

CPC classification number: A61B5/1459 ,  A61N1/36557

Abstract: An implantable medical sensor (42) determines the oxygen content of blood. The sensor includes a miniaturized hybrid circuit (130) that includes light-emitting diode means (32), phototransistor means (34, 36), and a substrate (110) to which the light-emitting diode means and phototransistor means are bonded in a desired circuit configuration. The hybrid circuit is hermetically sealed within a cylindrical body (140) made from a material that is substantially transparent to light, such as glass. Feedthrough terminals (132, 134) provide means for making an electrical connection with the hybrid circuit. The light-emitting diode means is driven with a stair-stepped current pulse. In one embodiment, the sensor is embedded within a bilumen pacemaker lead (60) and positioned near the distal electrode (66) of the lead so that the sensor resides within the heart when the lead is implanted within a patient, thereby allowing the sensed oxygen content (MVO.sub.2 concentration) of the blood within the heart to be a physiological parameter that can be used to control the pacing interval of a rate-responsive pacemaker (56).

Abstract translation: 可植入医疗传感器（42）确定血液的氧含量。 传感器包括小型化混合电路（130），其包括发光二极管装置（32），光电晶体管装置（34,36）和基板（110），发光二极管装置和光电晶体管装置连接到基板 所需电路配置。 混合电路气密地密封在由对玻璃基本上透明的材料制成的圆柱体（140）内。 馈通端子（132,134）提供用于与混合电路进行电连接的装置。 发光二极管装置由阶梯式电流脉冲驱动。 在一个实施例中，传感器被嵌入在胆囊起搏器引线（60）内并且定位在引线的远端电极（66）附近，使得当引线植入患者体内时，传感器驻留在心脏内，从而允许感测的氧气 心脏内血液的含量（MVO2浓度）成为可用于控制起搏器起搏间隔的生理参数（56）。