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    Device and method for assessing the geometry of a heart valve
    1.
    发明授权
    Device and method for assessing the geometry of a heart valve 失效
    用于评估心脏瓣膜几何形状的装置和方法

    公开(公告)号：US06678962B1

    公开(公告)日：2004-01-20

    申请号：US09716140

    申请日：2000-11-17

    申请人： Jack W. Love ,  James G. Hanlon

    发明人： Jack W. Love ,  James G. Hanlon

    IPC分类号： A61B5103

    CPC分类号： A61B5/1076 ,  A61F2/2427 ,  A61F2/2496 ,  A61F2250/0097

    摘要： A sizer for assessing the geometry of a heart valve annulus. The sizer preferably includes a circular sizing portion for measuring the diameter of the valve annulus. The sizing portion has radial spokes. The spokes are used to compare the symmetry of the commissures to the expected symmetry of a normal heart valve. The sizer preferably has one or more legs attached to the sizing portion for comparing the contour of the line of valve leaflet attachment to the expected contour of a normal heart valve having a diameter substantially equivalent to the measured diameter of the valve annulus.

    摘要翻译： 用于评估心脏瓣膜环的几何形状的分级器。 分级器优选地包括用于测量阀环直径的圆形施胶部分。 上胶部分具有径向辐条。 轮辐用于将合缝的对称性与正常心脏瓣膜的预期对称性进行比较。 分级器优选地具有连接到施胶部分的一个或多个腿，用于将瓣膜附件的线的轮廓与正常心脏瓣膜的预期轮廓进行比较，所述正常心脏瓣膜的直径基本上等于所测量的瓣膜环的直径。

    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
    2.
    发明授权
    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment 失效
    快速组装，同心配合支架，组织心脏瓣膜，增强夹紧和组织对齐

    公开(公告)号：US5326371A

    公开(公告)日：1994-07-05

    申请号：US925589

    申请日：1992-08-03

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. A plurality of prefabricated kits are also provided which enable the valve to be assembled with autogenous tissue in the limited time, i.e., 10 minutes or less, available in the operating room. The inner stent can be configured with a plurality of tissue alignment members extending outward from the inner stent to corresponding holes cut in the tissue. The outer stent can be configured with posts adapted for nesting with corresponding inner stent posts, and integrated with self-adjusting tensioning means, to exert a substantially uniform clamping force on the tissue sufficient to secure the tissue between the stents.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 还提供了多个预制试剂盒，其能够在手术室中可用的有限时间（即10分钟或更短）内与自体组织组装瓣膜。 内支架可以配置有从内支架向外延伸到在组织中切割的相应孔的多个组织对准构件。 外支架可以构造成具有适于与对应的内支架柱嵌套的柱并且与自调节张紧装置集成的柱，以在组织上施加足以将组织固定在支架之间的基本上均匀的夹紧力。

    Surgical cutting device
    3.
    发明授权
    Surgical cutting device 失效
    手术切割装置

    公开(公告)号：US07208000B2

    公开(公告)日：2007-04-24

    申请号：US10898505

    申请日：2004-07-23

    申请人： Jack W. Love

    发明人： Jack W. Love

    IPC分类号： A61B17/32

    CPC分类号： A61B17/32093 ,  A61B17/32 ,  A61B17/322 ,  A61B2017/00969 ,  A61F2/2415 ,  Y10T83/8782

    摘要： The present invention provides a single-use surgical cutting device for cutting a planar piece of tissue into a predetermined shape. The cutting device comprises a housing having one or more side walls, a top, a base, and a hollow interior portion. A blade retaining member is disposed within the housing between and substantially parallel to the top and base such that the blade retaining member can move vertically between the top and base. A blade defining a predetermined tissue shape is disposed on the bottom surface of the blade retaining member. A pressure mechanism creates potential energy for exerting a downward force on the top surface of the blade retaining member, such that when the blade retaining member is released, the pressure mechanism forces the blade retaining member downward with sufficient force to cut the piece of tissue. An actuator is configured to release the blade retaining member only once without disassembling the housing and resetting the pressure mechanism. Thus, a piece of tissue can be placed beneath the bottom surface of the blade retaining member on or parallel to the base and the actuating mechanism can be actuated to release the downward force on the blade retaining member to cut the piece of tissue into the desired shape, but the cutting device cannot readily be reused by an operator.

    摘要翻译： 本发明提供了一种用于将平面片组织切割成预定形状的一次性外科切割装置。 切割装置包括具有一个或多个侧壁，顶部，基部和中空内部部分的壳体。 叶片保持构件设置在壳体之间并且基本上平行于顶部和底部，使得叶片保持构件可以在顶部和底部之间垂直移动。 限定了组织形状的刀片设置在刀片保持部件的底面上。 压力机构产生用于在刀片保持构件的顶表面上施加向下的力的势能，使得当刀片保持构件被释放时，压力机构以足够的力向下迫使刀片保持构件以切割该片组织。 致动器构造成仅拆卸一次叶片保持构件而不拆卸壳体并重新设置压力机构。 因此，一片组织可以放置在刀片保持构件的底表面下方或平行于底座上，并且致动机构可以被致动以释放刀片保持构件上的向下的力，以将该组织切割成期望的 形状，但是切割装置不能容易地被操作者重复使用。

    Device and method for assessing the geometry of a heart valve
    4.
    发明授权
    Device and method for assessing the geometry of a heart valve 失效

    公开(公告)号：US06598307B2

    公开(公告)日：2003-07-29

    申请号：US09928740

    申请日：2001-08-13

    申请人： Jack W. Love ,  James G. Hanlon

    发明人： Jack W. Love ,  James G. Hanlon

    IPC分类号： A61B5103

    CPC分类号： A61F2/2496 ,  A61B5/1076 ,  A61F2/2427 ,  A61F2250/0097

    摘要： A sizer for assessing the geometry of a heart valve annulus including a handle portion for holding the sizer and a sizing portion. The sizing portion is preferably in the shape of an arch having an apex and two legs, each of which has a base adjoining the handle portion. The legs of the arched sizing portion are separated from each other by a predetermined distance that corresponds to the expected separation of commissures of a normal heart valve annulus. The height of the arch (measured from the base of each leg to the apex) corresponds to a predetermined leaflet height that approximates the expected height of a leaflet of a normal heart valve. For aortic valve reconstruction, the instrument is inserted into the opened aortic root following removal of the native valve tissue and is used to assess the distance between the commissures, the leaflet height, and the symmetry of the commissures of the exposed valve annulus.

    Products and methods for circulatory system valve repair
    5.
    发明授权
    Products and methods for circulatory system valve repair 失效
    循环系统阀门维修的产品和方法

    公开(公告)号：US6129758A

    公开(公告)日：2000-10-10

    申请号：US726342

    申请日：1996-10-03

    申请人： Jack W. Love

    发明人： Jack W. Love

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2496 ,  A61F2/2415 ,  A61F2/2427

    摘要： A standardized and reproducible method and instruments related thereto for repair of atrio-ventricular, aortic and pulmonary valves is provided.

    摘要翻译： 提供了一种用于修复房室，主动脉和肺动脉瓣的相关的标准化和可重现的方法和仪器。

    Stents for autologous tissue heart valve
    6.
    发明授权
    Stents for autologous tissue heart valve 失效
    自体组织心脏瓣膜支架

    公开(公告)号：US5755782A

    公开(公告)日：1998-05-26

    申请号：US169336

    申请日：1993-12-17

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2415 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2472 ,  Y10S623/90

    摘要： An improved set of stents for autologous tissue heart valves is provided. The stents are designed with the aid of a computer-aided-design (CAD) system, and nest within each other to securely clamp a piece of tissue which forms the leaflets of the heart valve. The geometrical features of the stents are designed to provide uniform nesting between the stents to prevent the formation of stress raisers on the tissue. Additionally, the windows in the stent posts are narrowed to prevent the suturing needle used during implantation of the valve from becoming lodged in the garter springs which clamp the outer stent to the inner stent. Finally, the sock covering the outer stent is bonded to the stent base at both upper and lower locations to isolate the bonds from the patient's blood flow.

    摘要翻译： 提供了一套改进的自体组织心脏瓣膜支架。 支架是借助于计算机辅助设计（CAD）系统设计的，并且彼此嵌套，以牢固地夹紧形成心脏瓣膜传单的一块组织。 支架的几何特征被设计成在支架之间提供均匀的嵌套，以防止在组织上形成应力集中器。 此外，支架柱中的窗口变窄，以防止在植入瓣膜期间使用的缝合针插入到将支架夹持在内支架上的套管弹簧中。 最后，覆盖外支架的袜子在上部和下部位置处与支架基座结合，以将粘合物与病人的血流隔离开来。

    Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure
    8.
    发明授权
    Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure 失效
    快速组装同心配合支架，组织心脏瓣膜增强夹紧和组织暴露

    公开(公告)号：US5489298A

    公开(公告)日：1996-02-06

    申请号：US400466

    申请日：1995-03-07

    申请人： Charles S. Love ,  Jack W. Love

    发明人： Charles S. Love ,  Jack W. Love

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2472 ,  A61F2/2412 ,  A61F2/2415 ,  Y10S623/90

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. The valve comprises at least one piece of tissue clamped between an inner and an outer stent. The outer stent is configured with a plurality of spaced posts extending from a base, wherein the posts are configured with open windows so that at least a portion of the tissue in the assembled valve is exposed through the windows. Several embodiments of the outer stent are disclosed, including where the outer stent comprises a crimped metal wire frame covered with a Dacron tube.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 该阀包括夹在内支架和外支架之间的至少一片组织。 外支架构造有从基部延伸的多个间隔开的柱，其中柱被构造成具有开放的窗口，使得组装的阀中的组织的至少一部分通过窗户暴露。 公开了外支架的几个实施例，包括外支架包括被涤纶管覆盖的卷曲金属线框架的位置。

    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
    9.
    发明授权
    Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment 失效
    快速组装，同心配合支架，组织心脏瓣膜，增强夹紧和组织对齐

    公开(公告)号：US5423887A

    公开(公告)日：1995-06-13

    申请号：US925380

    申请日：1992-08-03

    申请人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    发明人： Charles S. Love ,  Jack W. Love ,  John H. Calvin

    IPC分类号： A61M1/10 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2472 ,  A61F2/2496 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S623/90 ,  Y10S623/901 ,  Y10S623/91 ,  Y10S623/913 ,  Y10S623/918 ,  Y10T137/7857 ,  Y10T29/49405

    摘要： A concentric mating stent tissue heart valve which is capable of being assembled with a variety of tissue sources is provided. A plurality of prefabricated kits are also provided which enable the valve to be assembled with autogenous tissue in the limited time, i.e., 10 minutes or less, available in the operating room. The inner stent can be configured with a plurality of tissue alignment members extending outward from the inner stent to corresponding holes cut in the tissue. The outer stent can be configured with posts adapted for nesting with corresponding inner stent posts, and integrated with self-adjusting tensioning means, to exert a substantially uniform clamping force on the tissue sufficient to secure the tissue between the stents.

    摘要翻译： 提供能够与各种组织源组装的同心配合的支架组织心脏瓣膜。 还提供了多个预制试剂盒，其能够在手术室中可用的有限时间（即10分钟或更短）内与自体组织组装瓣膜。 内支架可以配置有从内支架向外延伸到在组织中切割的相应孔的多个组织对准构件。 外支架可以构造成具有适于与对应的内支架柱嵌套的柱并且与自调节张紧装置集成的柱，以在组织上施加足以将组织固定在支架之间的基本上均匀的夹紧力。