-
公开(公告)号：US6099865A
公开(公告)日：2000-08-08
申请号：US330445
申请日：1999-06-11
CPC分类号： A61K9/1652 , A61K9/0056 , A61K9/5047 , A61K9/2054 , A61K9/2077 , A61K9/2081
摘要： The present invention describes the use of croscarmellose sodium to coat bitter-tasting active agents in a manner that will mask the bitter taste of these materials, taste masked pharmaceutical compositions in which the particles of pharmaceutically active agent are coated with croscarmellose sodium, taste masked pharmaceutical tablets made therefrom, in which the rapid disintegration of tablets that is imparted by croscarmellose sodium is preserved, and to a method for preparing such coated particles by preparing them in a fluidized bed coating process.
摘要翻译： 本发明描述了使用交联羧甲基纤维素钠以掩蔽这些材料的苦味的方式涂上苦味活性剂，其中药物活性剂颗粒用交联羧甲纤维素钠涂覆的掩味药物组合物，掩味药剂 由其制备的片剂，其中保存了由交联羧甲基纤维素钠赋予的片剂的快速崩解，以及通过在流化床包衣方法中制备这些包衣颗粒的方法。
-
公开(公告)号：US5858409A
公开(公告)日：1999-01-12
申请号：US785228
申请日：1996-04-17
CPC分类号： A61K9/2054
摘要： The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.
摘要翻译： 本发明提供了制备用于制备药用片剂的喷雾干燥的可压缩颗粒制剂的方法，其中使用水解纤维素作为造粒助剂，所得颗粒和从这种颗粒压制的药物片剂。 在这些制剂中，使用1至97重量％的药物活性剂，约3至99重量％的水解纤维素，基于造粒物的干重，以及任选的常规制粒和/或压片添加剂，例如表面活性剂，崩解剂 和抗粘附剂/助流剂。
-
搜索结果
2 条记录 (耗时 0.009 秒)
