公开(公告)号：US20230125690A1

公开(公告)日：2023-04-27

申请号：US17753702

申请日：2020-09-18

Applicant: Jae-Sung BAE ,  Hee Kyung JIN ,  Ju Youn LEE

Inventor： Jae-Sung BAE ,  Hee Kyung JIN ,  Ju Youn LEE

IPC: G01N33/573 ,  G01N33/68 ,  C07K16/40 ,  C07K16/44 ,  A61P25/28

Abstract: The present invention relates to an antibody for detecting acetylation of COX2 protein, and uses thereof, and more specifically, to an antibody that specifically recognizes the acetylation of S565 residue of the COX2 protein; and uses thereof for diagnosing neurodegenerative diseases or inflammatory diseases. An antibody or a functional fragment thereof according to the present invention specifically binds to an acetylated residue of COX2 protein, and can thus be very effectively used for diagnosing neurodegenerative diseases, inflammatory diseases, and the like in which the degree of acetylation of S565 residue of the COX2 protein is reduced.