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公开(公告)号：US06994688B2
公开(公告)日：2006-02-07
申请号：US09858366
申请日：2001-05-16
IPC分类号： A61M29/00
CPC分类号： A61N5/1002 , A61N2005/1004
摘要： A catheter for the positioning of a radioactive material for therapeutic radiation treatment of the body is disclosed. The catheter includes a radioactive source positioned at the distal end thereof and is sufficiently flexible and strong to navigate in the body to the desired treatment location. The radioactive source may be provided to the catheter in a number of different ways. In one set of embodiments, the radioactive source is bonded to the inner or outer surface of the catheter body, a catheter attachment or a carrier positionable within the catheter body. In another set of embodiments, one of the catheter body, catheter attachment or carrier positionable within the catheter body includes a cavity within which the radioactive source is placed. In this set of embodiments, the radioactive source may be provided in a variety of different forms, depending upon the particular needs of the treatment method. The radioactive source may also be immobilized in a polymeric material such as an elastomer, gel, hydrogel, foam or other similar deformable material. Finally, the catheter body or carrier may include a removable portion which provides access to the cavity within which the radioactive source is housed.
摘要翻译： 公开了一种用于定位用于体内治疗性放射治疗的放射性物质的导管。 导管包括位于其远端处的放射源，并且具有足够的柔性和强度以在体内导航到期望的治疗位置。 可以以多种不同的方式将放射源提供给导管。 在一组实施例中，放射源结合到导管主体的内表面或外表面，导管附件或可定位在导管主体内的载体。 在另一组实施例中，可以在导管主体内定位的导管主体，导管附接件或载体之一包括其中放置放射源的空腔。 在这组实施例中，放射源可以以各种不同形式提供，这取决于治疗方法的特定需要。 放射源也可以固定在聚合材料如弹性体，凝胶，水凝胶，泡沫或其它类似的可变形材料中。 最后，导管主体或载体可以包括提供对容纳放射源的腔的通路的可移除部分。
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公开(公告)号：US06531705B2
公开(公告)日：2003-03-11
申请号：US09969393
申请日：2001-10-02
IPC分类号： G21F500
CPC分类号： G21F5/015 , G21Y2002/301 , G21Y2002/305 , G21Y2002/501 , G21Y2004/30
摘要： A container for storing and transporting device containing radioactive materials used for medical procedures is disclosed. Such devices may include a radioactive shielding material which contains a portion of the radioactivity emitted by the radioactive material. The container has an upper portion and a lower portion, and at least one of the portions includes a radiation shielding material, such as lead, steel or other appropriate shielding materials. Devices containing radioactive material are placed within the container. The container secures the devices against lateral movement within the container. The radiation shielding material of the lower portion of the container may cooperate with the radiation shielding material of the device to contain more of the emitted radiation than is contained by the device alone. The container and the holder may be sterilizable to allow such devices to be transported and sterilized for medical use.
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公开(公告)号：US06323501B1
公开(公告)日：2001-11-27
申请号：US09266867
申请日：1999-03-12
IPC分类号： G21F500
CPC分类号： G21F5/015 , G21Y2002/301 , G21Y2002/305 , G21Y2002/501 , G21Y2004/30
摘要： A container for storing and transporting device containing radioactive materials used for medical procedures is disclosed. Such devices may include a radioactive shielding material which contains a portion of the radioactivity emitted by the radioactive material. The container has an upper portion and a lower portion, and at least one of the portions includes a radiation shielding material, such as lead, steel or other appropriate shielding materials. Devices containing radioactive material are placed within the container. The container secures the devices against lateral movement within the container. The radiation shielding material of the lower portion of the container may cooperate with the radiation shielding material of the device to contain more of the emitted radiation than is contained by the device alone. The container and the holder may be sterilizable to allow such devices to be transported and sterilized for medical use.
摘要翻译： 公开了一种用于存储和运输用于医疗程序的放射性物质的容器。 这种装置可以包括放射性屏蔽材料，其包含由放射性物质发射的放射性的一部分。 容器具有上部和下部，并且至少一个部分包括辐射屏蔽材料，例如铅，钢或其它合适的屏蔽材料。 装有放射性物质的装置放置在容器内。 容器固定装置以防止容器内的横向移动。 容器下部的辐射屏蔽材料可以与装置的辐射屏蔽材料配合，以容纳比单独装置所含的更多的发射辐射。 容器和保持器可以是可消毒的，以允许将这些装置运输和消毒用于医疗用途。
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公开(公告)号：US06749553B2
公开(公告)日：2004-06-15
申请号：US09858816
申请日：2001-05-16
IPC分类号： A61N500
CPC分类号： A61N5/1027 , A61N2005/1023 , A61N2005/1025
摘要： Radiation delivery devices useful in brachytherapy which employ radioactive palladium-103 as the radiation source material are disclosed. Certain embodiments of the disclosed radiation delivery devices have the advantages that they can be fabricated with the desired specific activity, that the self-shielding effects of the devices are minimized, that the radioactive source material is bonded to a substrate in a manner which substantially prevents it from becoming detached, and that a variety of customizable radiation delivery devices can be made using the concepts of the invention. Also disclosed are processes for bonding radiation source material to various substrates using electroless plating, chemical vapor deposition and polymer matrices. These processes have the advantage that they can be applied to bond the radiation source material to a wide variety of substrates including different substrate materials and differently shaped substrates, thereby providing the ability to tailor the radiation delivery devices to the specific requirements of a particular brachytherapy treatment.
摘要翻译： 公开了使用放射性钯-103作为辐射源材料的用于近距离放射治疗的辐射递送装置。 所公开的辐射递送装置的某些实施例具有这样的优点：它们可以以期望的比活度制造，使得装置的自屏蔽作用最小化，放射源材料以基本上防止的方式结合到基底 它变得分离，并且可以使用本发明的概念制造各种可定制的辐射递送装置。 还公开了使用化学镀，化学气相沉积和聚合物基质将辐射源材料粘合到各种基底的方法。 这些方法具有这样的优点：它们可以用于将辐射源材料粘合到包括不同基底材料和不同形状的基底的各种基底上，从而提供根据特定近距离放射疗法治疗的具体要求来定制辐射递送装置的能力 。
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公开(公告)号：US06664555B2
公开(公告)日：2003-12-16
申请号：US10369045
申请日：2003-02-19
IPC分类号： G21F500
CPC分类号： G21F5/015 , G21Y2002/301 , G21Y2002/305 , G21Y2002/501 , G21Y2004/30
摘要： A container for storing and transporting device containing radioactive materials used for medical procedures is disclosed. Such devices may include a radioactive shielding material which contains a portion of the radioactivity emitted by the radioactive material. The container has an upper portion and a lower portion, and at least one of the portions includes a radiation shielding material, such as lead, steel or other appropriate shielding materials. Devices containing radioactive material are placed within the container. The container secures the devices against lateral movement within the container. The radiation shielding material of the lower portion of the container may cooperate with the radiation shielding material of the device to contain more of the emitted radiation than is contained by the device alone. The container and the holder may be sterilizable to allow such devices to be transported and sterilized for medical use.
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