公开(公告)号：US20070134185A1

公开(公告)日：2007-06-14

申请号：US10555788

申请日：2004-05-04

申请人： Henri Samain ,  Gilles Genain ,  Aude Livoreil ,  Gabin Vic

发明人： Henri Samain ,  Gilles Genain ,  Aude Livoreil ,  Gabin Vic

IPC分类号： A61K8/58

CPC分类号： A61K8/498 ,  A61K8/46 ,  A61K8/4986 ,  A61K8/60 ,  A61Q5/04

摘要： The subject of the invention is the use of particular dithiols in a composition for permanent deformation of hair. It also relates to a method for permanent deformation of hair using these dithiols, and cosmetic compositions containing at least one of these dithiols and at least one compound chosen from nonionic, anionic, cationic, amphoteric or zwitterionic polymers and surfactants or cosmetic compositions containing specific dithiols.

摘要翻译： 本发明的主题是在组合物中使用特定的二硫醇以使头发永久变形。 它还涉及一种使用这些二硫醇使毛发永久变形的方法，以及包含这些二硫醇和至少一种选自非离子，阴离子，阳离子，两性或两性离子聚合物和表面活性剂或含有特定二硫醇的化妆品组合物中的至少一种的化妆品组合物 。

公开(公告)号：US20060080791A1

公开(公告)日：2006-04-20

申请号：US11249357

申请日：2005-10-14

申请人： Nicolas Daubresse ,  Gilles Genain

发明人： Nicolas Daubresse ,  Gilles Genain

IPC分类号： A61K8/00

CPC分类号： A61Q5/10 ,  A61K8/46 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4953 ,  A61K8/4966

摘要： Disclosed herein is a dyeing composition comprising a particular disulphide dye and a method of dyeing human keratin fibers, such as hair, using this composition. This composition makes it possible to obtain particularly fast chromatic colorations.

公开(公告)号：US5072006A

公开(公告)日：1991-12-10

申请号：US630092

申请日：1990-12-19

申请人： Gilles Genain ,  Henri Pinhas

发明人： Gilles Genain ,  Henri Pinhas

IPC分类号： C07D311/68 ,  C07D311/70 ,  C07D405/04

CPC分类号： C07D405/04 ,  C07D311/68 ,  C07D311/70

摘要： Compounds of the formula ##STR1## wherein: R.sub.1 is cyano or nitro;R.sub.2 and R.sub.3 are independently hydrogen or lower alkyl; andR.sub.4 is alkyl; alkenyl; optionally substituted phenyl or phenyl lower alkyl; --(CH.sub.2).sub.m OR.sub.2 or --(CH.sub.2).sub.m N(R.sub.2).sub.2 ; wherein m is an integer of 1-5 and R.sub.2 is as defined above;or a pharmaceutically acceptable ester thereof; are smooth muscle relaxants, particularly useful in the treatment of hypertension.

摘要翻译： 式（I）的化合物其中：R 1是氰基或硝基; R2和R3独立地是氢或低级烷基; 和R4是烷基; 烯基; 任选取代的苯基或苯基低级烷基; - （CH 2）m OR 2或 - （CH 2）m N（R 2）2; 其中m是1-5的整数，R2如上所定义; 或其药学上可接受的酯; 是平滑肌松弛剂，特别适用于治疗高血压。

公开(公告)号：US4761420A

公开(公告)日：1988-08-02

申请号：US874264

申请日：1986-06-13

申请人： Gilles Genain

发明人： Gilles Genain

IPC分类号： A61K31/443 ,  A61K31/455 ,  A61P9/12 ,  C07D211/90 ,  C07D309/30 ,  C07D405/12

CPC分类号： C07D405/12 ,  C07D211/90 ,  C07D309/30

摘要： Compound of formula 1 are calcium entry antagonists useful for treating hypertension, congestive heart failure, angina, and vasospastic disorders: ##STR1## wherein n is an integer from 1 to 4;R.sub.1 and R.sub.2 are lower alkyl;R.sub.3 is lower alkyl or alkoxyalkyl;A is alkylene of two to eight carbon atoms;X.sub.1 and X.sub.2 are each independently --NO.sub.2, --CF.sub.3, CH.sub.3 O--, --CN, --H, lower alkyl or halo;Y is --O--, --S--, --S(O)--, or --S(O).sub.2 --; andR is H, lower alkyl, cycloalkyl, alkoxyalkyl, cycloalkyloxy-alkyl, alkoxycycloalkyl, acyl, or saturated or unsaturated 5- or 6-membered heterocyclyl optionally substituted with lower alkyl or alkoxy, wherein the heteroatom is one oxygen atom.

摘要翻译： 式1的化合物是可用于治疗高血压，充血性心力衰竭，心绞痛和血管痉挛性障碍的钙进入拮抗剂：其中n是1至4的整数; R1和R2是低级烷基; R3是低级烷基或烷氧基烷基; A是2至8个碳原子的亚烷基; X 1和X 2各自独立地为-NO 2，-CF 3，CH 3 O + 13，-CN，-H，低级烷基或卤素; Y是-O - ， - S - ， - S（O） - 或-S（O）2 - ; 并且R是H，低级烷基，环烷基，烷氧基烷基，环烷氧基 - 烷基，烷氧基环烷基，酰基或任选被低级烷基或烷氧基取代的饱和或不饱和的5-或6-元杂环基，其中杂原子是一个氧原子。

公开(公告)号：US08597373B2

公开(公告)日：2013-12-03

申请号：US13701827

申请日：2011-06-13

申请人： Frédéric Guerin ,  Gilles Genain ,  Patrick Choisy

发明人： Frédéric Guerin ,  Gilles Genain ,  Patrick Choisy

IPC分类号： A61Q5/10

CPC分类号： A61K8/492 ,  A61K8/19 ,  A61K8/22 ,  A61K8/27 ,  A61K2800/4324 ,  A61Q5/10

摘要： The invention relates to a process for dyeing keratin fibers, in which said fibers are treated: ▪ with a composition (A) comprising i) one or more indole or indoline compounds; ii) one or more metal salts; iii) hydrogen peroxide or one or more systems that generate hydrogen peroxide; and then ▪ with a composition (B) comprising iv) one or more basifying agents. The invention also relates to a hair dyeing process for obtaining better colorations, which are more uniform, chromatic and remanent and which do not impair the cosmetic properties of keratin fibers.

摘要翻译： 本发明涉及染色角蛋白纤维的方法，其中处理所述纤维：*组合物（A），其包含i）一种或多种吲哚或二氢吲哚化合物; ii）一种或多种金属盐; iii）过氧化氢或一种或多种产生过氧化氢的体系; 然后用组合物（B）包含iv）一种或多种碱化剂。 本发明还涉及一种用于获得更好的着色的染发方法，其更均匀，有色和残留，并且不损害角蛋白纤维的化妆品性质。

公开(公告)号：US20130174864A1

公开(公告)日：2013-07-11

申请号：US13701827

申请日：2011-06-13

申请人： Frédéric Guerin ,  Gilles Genain ,  Patrick Choisy

发明人： Frédéric Guerin ,  Gilles Genain ,  Patrick Choisy

IPC分类号： A61K8/49 ,  A61Q5/10

CPC分类号： A61K8/492 ,  A61K8/19 ,  A61K8/22 ,  A61K8/27 ,  A61K2800/4324 ,  A61Q5/10

摘要： The invention relates to a process for dyeing keratin fibers, in which said fibers are treated: ▪ with a composition (A) comprising i) one or more indole or indoline compounds; ii) one or more metal salts; iii) hydrogen peroxide or one or more systems that generate hydrogen peroxide; and then ▪ with a composition (B) comprising iv) one or more basifying agents. The invention also relates to a hair dyeing process for obtaining better colorations, which are more uniform, chromatic and remanent and which do not impair the cosmetic properties of keratin fibers.

摘要翻译： 本发明涉及染色角蛋白纤维的方法，其中处理所述纤维：*组合物（A），其包含i）一种或多种吲哚或二氢吲哚化合物; ii）一种或多种金属盐; iii）过氧化氢或一种或多种产生过氧化氢的体系; 然后用组合物（B）包含iv）一种或多种碱化剂。 本发明还涉及一种用于获得更好的着色的染发方法，其更均匀，有色和残留，并且不损害角蛋白纤维的化妆品性质。

公开(公告)号：US4920225A

公开(公告)日：1990-04-24

申请号：US945760

申请日：1986-12-22

申请人： Gilles Genain

发明人： Gilles Genain

IPC分类号： A61K20060101 ,  C07D20060101 ,  C07D211/90

CPC分类号： C07D211/90

摘要： Optically active compounds of formula 1 ##STR1## wherein R.sub.1 is H or lower alkyl;R.sub.2 and R.sub.6 are each independently lower alkyl, aryl, or arylalkyl;R.sub.3 is CN, NO.sub.2, CO.sub.2 R.sub.5, CONHR.sub.5, SO.sub.2 R.sub.5, or P(O)(OR.sub.5).sub.2, where R.sub.5 is lower alkyl, lower alkoxyalkyl, aryl, or arylalkyl;R.sub.4 is aryl, heterocyclyl, or fused-ring heterocyclyl, optionally substituted with one, two, or three halo, NO.sub.2, CN, lower alkyl, lower alkoxy, lower alkylamino, CF.sub.3, OCH.sub.2 F, or OCF.sub.3 ;are prepared by fractional crystallization from hot organic solvent and water in the presence of a suitable optically active amine base.

公开(公告)号：US09775419B2

公开(公告)日：2017-10-03

申请号：US13697281

申请日：2011-05-11

申请人： Gilles Genain ,  Gabin Vic ,  Stefania Nuzzo ,  Marie Muller

发明人： Gilles Genain ,  Gabin Vic ,  Stefania Nuzzo ,  Marie Muller

IPC分类号： A45D7/02 ,  A45D7/06 ,  A45D1/04 ,  A45D2/00 ,  A45D1/00

CPC分类号： A45D7/06 ,  A45D1/04 ,  A45D2/001 ,  A45D2001/008 ,  A45D2200/207

摘要： The present invention relates to a cosmetic hair treatment method comprising at least the steps consisting of: a) applying a mechanical tension to said hair, b) exposing said hair under mechanical tension to microwaves, in the presence of a solvent in vapor form in contact with said hair, without complete drying of the hair during microwave exposure, the solvent in vapor form being entirely generated by the evaporation of a compound which is present, before emission of the microwaves, in contact with the treated hair.

公开(公告)号：US20130152959A1

公开(公告)日：2013-06-20

申请号：US13697281

申请日：2011-05-11

申请人： Gilles Genain ,  Gabin Vic ,  Stefania Nuzzo ,  Marie Muller

发明人： Gilles Genain ,  Gabin Vic ,  Stefania Nuzzo ,  Marie Muller

IPC分类号： A45D7/06

CPC分类号： A45D7/06 ,  A45D1/04 ,  A45D2/001 ,  A45D2001/008 ,  A45D2200/207

摘要： The present invention relates to a cosmetic hair treatment method comprising at least the steps consisting of: a) applying a mechanical tension to said hair, b) exposing said hair under mechanical tension to microwaves, in the presence of a solvent in vapour form in contact with said hair, without complete drying of the hair during microwave exposure, the solvent in vapour form being entirely generated by the evaporation of a compound which is present, before emission of the microwaves, in contact with the treated hair.

摘要翻译： 本发明涉及一种化妆品头发处理方法，其至少包括以下步骤：a）对所述头发施加机械张力，b）在机械张力下将所述毛发暴露于微波中，在存在蒸气形式的溶剂的存在下接触 与所述头发，在微波暴露期间没有完全干燥毛发，蒸气形式的溶剂完全通过在发射微波之前与经处理的毛发接触而存在的化合物的蒸发完全产生。

公开(公告)号：US20130074862A1

公开(公告)日：2013-03-28

申请号：US13685443

申请日：2012-11-26

申请人： David W. CANNELL ,  Cynthia Chong ESPINO ,  Nghi Van NGUYEN ,  Gilles GENAIN

发明人： David W. CANNELL ,  Cynthia Chong ESPINO ,  Nghi Van NGUYEN ,  Gilles GENAIN

IPC分类号： A45D7/06

CPC分类号： A45D7/06 ,  A61K8/19 ,  A61K8/24 ,  A61K8/36 ,  A61K8/365 ,  A61K8/41 ,  A61K8/411 ,  A61K8/49 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/4966 ,  A61K2800/24 ,  A61Q5/04

摘要： A process for straightening or relaxing hair involving the steps of: (a) pre-alkalizing the hair by contacting it with an alkaline composition having a pH of from about 8.0 to about 10.5 to form pre-alkalized hair; (b) optionally, rinsing the alkaline composition from the pre-alkalized hair; (c) providing a hair straightening/relaxing composition containing: (i) from about 0.1 to about 50% by weight of at least one weak non-hydroxide base; and (ii) remainder, to 100%, a cosmetically acceptable medium, all weights based on the weight of the hair straightening/relaxing composition; (d) contacting the hair with the hair straightening/relaxing composition to form treated hair; (e) optionally, rinsing the hair straightening/relaxing composition from the treated hair; (f) optionally, contacting the treated hair with a non-volatile oil; and (g) smoothing the treated hair using a combination of heat and means for physically smoothing hair.

摘要翻译： 一种矫直或松弛头发的方法，包括以下步骤：（a）通过使毛发与pH为约8.0至约10.5的碱性组合物进行预碱化以形成预碱化头发; （b）任选地，从所述预碱化头发冲洗所述碱性组合物; （c）提供一种头发矫直/松弛组合物，其包含：（i）约0.1至约50重量％的至少一种弱非氢氧化物碱; 和（ii）剩余部分至100％的化妆品可接受的培养基，所有重量均基于毛发矫直/松弛组合物的重量; （d）使头发与头发矫直/放松组合物接触以形成被处理的头发; （e）任选地，从经处理的头发漂洗毛发矫直/松弛组合物; （f）任选地，使经处理的毛发与非挥发性油接触; 和（g）使用热的组合和用于物理上平滑头发的装置来平滑处理过的毛发。