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    Catheter with attached flexible side sheath
    1.
    发明授权
    Catheter with attached flexible side sheath 有权
    导管附有柔性侧护套

    公开(公告)号：US09561126B2

    公开(公告)日：2017-02-07

    申请号：US13534720

    申请日：2012-06-27

    申请人： Gil M. Vardi ,  Charles J. Davidson ,  Eric Williams

    发明人： Gil M. Vardi ,  Charles J. Davidson ,  Eric Williams

    IPC分类号： A61F2/954 ,  A61F2/958 ,  A61F2/856

    CPC分类号： A61F2/954 ,  A61F2/856 ,  A61F2/958 ,  A61F2250/006 ,  A61F2250/0097 ,  Y10S623/903

    摘要： A method of positioning a main stent at a vessel bifurcation includes positioning a main guidewire in the main vessel; and advancing a stent delivery system to a position proximate the bifurcation. The stent delivery system includes a catheter with a flexible side sheath attached thereto and a main stent positioned over the catheter. The flexible side sheath is positioned to pass through the side opening in the main stent. The method also includes advancing a branch guidewire through the flexible side sheath and into the branch vessel; and subsequently, advancing the catheter over the main guidewire while advancing the flexible side sheath over the branch guidewire while viewing relative movement of a marker positioned on the flexible side sheath with respect to at least one marker positioned on the catheter.

    摘要翻译： 将主支架定位在血管分叉处的方法包括将主导丝定位在主血管中; 并将支架输送系统推进到靠近分叉的位置。 支架输送系统包括其上附着柔性侧鞘的导管和位于导管上的主支架。 柔性侧护套被定位成穿过主支架中的侧开口。 该方法还包括使分支导丝穿过柔性侧鞘并进入分支容器; 并且随后，当相对于位于导管上的至少一个标记物观察位于柔性侧护套上的标记物的相对运动时，将导管推进主导丝上，同时使柔性侧鞘超过分支导丝。

    SYSTEMS AND METHODS FOR MINIMALLY-INVASIVE OPTICAL-ACOUSTIC IMAGING
    2.
    发明申请
    SYSTEMS AND METHODS FOR MINIMALLY-INVASIVE OPTICAL-ACOUSTIC IMAGING 有权
    用于最小入射光学声像成像的系统和方法

    公开(公告)号：US20120108943A1

    公开(公告)日：2012-05-03

    申请号：US13285551

    申请日：2011-10-31

    申请人： Kenneth N. Bates ,  Gil M. Vardi

    发明人： Kenneth N. Bates ,  Gil M. Vardi

    IPC分类号： A61B6/00 ,  G01V1/145 ,  G02F1/335

    CPC分类号： A61B5/0095 ,  A61B1/00117 ,  A61B1/00165 ,  A61B5/0097 ,  A61B5/02007 ,  A61B5/6851 ,  A61B5/6876 ,  A61B5/742 ,  A61B8/0833 ,  A61B8/12 ,  G01H9/004 ,  G01N29/24 ,  G02B6/10

    摘要： An imaging guidewire can include optical fibers communicating light along the guidewire. At or near its distal end, one or more blazed or other fiber Bragg gratings (FBGs) directs light to a photoacoustic transducer material that provides ultrasonic imaging energy. Returned ultrasound is sensed by an FBG sensor. A responsive signal is optically communicated to the proximal end of the guidewire, and processed to develop a 2D or 3D image. The guidewire outer diameter is small enough such that an intravascular catheter can be passed over the guidewire. Techniques for improving ultrasound reception include using a high compliance material, resonating the ultrasound sensing transducer, using an attenuation-reducing coating and/or thickness, and/or using optical wavelength discrimination. Techniques for improving the ultrasound generating transducer include using a blazed FBG, designing the photoacoustic material thickness to enhance optical absorption. Techniques for distinguishing plaque or vulnerable plaque may enhance the displayed image.

    摘要翻译： 成像导丝可以包括沿导丝传送光的光纤。 在其远端处或附近，一个或多个闪耀或其它光纤布拉格光栅（FBG）将光引导到提供超声成像能量的光声换能器材料。 返回的超声波由FBG传感器感测。 响应信号被光学地传递到导丝的近端，并被处理以形成2D或3D图像。 导丝外径足够小，使得血管内导管可以穿过导​​丝。 用于改善超声波接收的技术包括使用高柔顺性材料，使用衰减减小涂层和/或厚度谐振超声波感测传感器和/或使用光波长鉴别。 用于改进超声波产生换能器的技术包括使用闪耀的FBG，设计光声材料厚度以增强光学吸收。 用于区分斑块或易损斑块的技术可以增强显示的图像。

    Extendible stent apparatus
    3.
    发明授权
    Extendible stent apparatus 有权
    可扩展支架装置

    公开(公告)号：US07892279B2

    公开(公告)日：2011-02-22

    申请号：US12472189

    申请日：2009-05-26

    申请人： Charles J. Davidson ,  Eric Williams ,  Gil M. Vardi ,  Stuart Lin

    发明人： Charles J. Davidson ,  Eric Williams ,  Gil M. Vardi ,  Stuart Lin

    IPC分类号： A61F2/06

    CPC分类号： A61F2/82 ,  A61F2/064 ,  A61F2/07 ,  A61F2/856 ,  A61F2/91 ,  A61F2/915 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/821 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2250/006 ,  A61F2250/0098

    摘要： The present invention concerns novel stent apparatuses for use in treating lesions at or near the bifurcation point in bifurcated cardiac, coronary, renal, peripheral vascular, gastrointestinal, pulmonary, urinary and neurovascular vessels and brain vessels. More particularly, the invention concerns a stent apparatus with at least one side opening which may further comprise an extendable stent portion laterally extending from the side opening and at least partly in registry with the wall of the side opening. Devices constructed in accordance with the invention include, singularly or in combination, a main expandable stent comprising at least one substantially circular side opening located between its proximal and distal end openings, which side opening may further comprise an expandable portion extending radially outward from the edges of the side opening; and a branch stent comprising proximal and distal end openings and which may further comprise a contacting portion at its proximal end, and which may optionally be constructed to form either a perpendicular branch or a non-perpendicular branch when inserted through a side opening of the main stent. The stents of the invention are marked with, or at least partially constructed of, a material which is imagable during intraluminal catheterization techniques, most preferably but not limited to ultrasound and x-ray.

    摘要翻译： 本发明涉及用于治疗分叉的心脏，冠状动脉，肾脏，外周血管，胃肠，肺，尿和神经血管血管和脑血管中的分叉点处或附近的病变的新型支架装置。 更具体地说，本发明涉及具有至少一个侧面开口的支架装置，所述至少一个侧面开口还可以包括从所述侧面开口横向延伸并且至少部分地与所述侧面开口的壁对齐的可延伸支架部分。 根据本发明构造的装置包括单独地或组合地包括主扩展支架，其包括位于其近端和远端开口之间的至少一个基本上圆形的侧开口，该侧开口还可包括从边缘径向向外延伸的可扩张部分 的侧面开口; 以及分支支架，其包括近端和远端开口，并且其可以在其近端处进一步包括接触部分，并且其可以可选地被构造成当插入通过主体的侧开口插入时垂直分支或非垂直分支 支架。 本发明的支架标记有或至少部分地由在腔内导管插入术技术中可成像的材料标记，或者至少部分地构成，最优选但不限于超声和X射线。

    Extendible Stent Apparatus
    5.
    发明申请
    Extendible Stent Apparatus 有权
    可扩展支架装置

    公开(公告)号：US20090240321A1

    公开(公告)日：2009-09-24

    申请号：US12472189

    申请日：2009-05-26

    申请人： Charles J. Davidson ,  Eric Williams ,  Gil M. Vardi ,  Stuart Lin

    发明人： Charles J. Davidson ,  Eric Williams ,  Gil M. Vardi ,  Stuart Lin

    IPC分类号： A61F2/06

    CPC分类号： A61F2/82 ,  A61F2/064 ,  A61F2/07 ,  A61F2/856 ,  A61F2/91 ,  A61F2/915 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/821 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2250/006 ,  A61F2250/0098

    摘要： The present invention concerns novel stent apparatuses for use in treating lesions at or near the bifurcation point in bifurcated cardiac, coronary, renal, peripheral vascular, gastrointestinal, pulmonary, urinary and neurovascular vessels and brain vessels. More particularly, the invention concerns a stent apparatus with at least one side opening which may further comprise an extendable stent portion laterally extending from the side opening and at least partly in registry with the wall of the side opening. Devices constructed in accordance with the invention include, singularly or in combination, a main expandable stent comprising at least one substantially circular side opening located between its proximal and distal end openings, which side opening may further comprise an expandable portion extending radially outward from the edges of the side opening; and a branch stent comprising proximal and distal end openings and which may further comprise a contacting portion at its proximal end, and which may optionally be constructed to form either a perpendicular branch or a non-perpendicular branch when inserted through a side opening of the main stent. The stents of the invention are marked with, or at least partially constructed of, a material which is imageable during intraluminal catheterization techniques, most preferably but not limited to ultrasound and x-ray.

    摘要翻译： 本发明涉及用于治疗分叉的心脏，冠状动脉，肾脏，外周血管，胃肠，肺，尿和神经血管血管和脑血管中的分叉点处或附近的病变的新型支架装置。 更具体地说，本发明涉及具有至少一个侧面开口的支架装置，所述至少一个侧面开口还可以包括从所述侧面开口横向延伸并且至少部分地与所述侧面开口的壁对齐的可延伸支架部分。 根据本发明构造的装置包括单独地或组合地包括主扩展支架，其包括位于其近端和远端开口之间的至少一个基本上圆形的侧开口，该侧开口还可包括从边缘径向向外延伸的可扩张部分 的侧面开口; 以及分支支架，其包括近端和远端开口，并且其可以在其近端处进一步包括接触部分，并且其可以可选地被构造成当插入通过主体的侧开口插入时垂直分支或非垂直分支 支架。 本发明的支架由管腔内导管插入技术中可成像的材料标记或至少部分地构成，最优选但不限于超声和x射线。

    Optical-acoustic imaging device
    9.
    发明授权
    Optical-acoustic imaging device 有权
    光声成像装置

    公开(公告)号：US06659957B1

    公开(公告)日：2003-12-09

    申请号：US09623248

    申请日：2002-06-11

    申请人： Gil M. Vardi ,  Victor Spivak

    发明人： Gil M. Vardi ,  Victor Spivak

    IPC分类号： A61B814

    CPC分类号： A61B8/12 ,  A61B5/0095 ,  A61B5/0097 ,  A61B8/56 ,  A61B2017/22042 ,  A61B2090/3614 ,  G01H9/004

    摘要： The present invention is a guide wire imaging device for vascular or non-vascular imaging utilizing optic acoustical methods, which device has a profile of less than 1 mm in diameter. The ultrasound imaging device of the invention comprises a single mode optical fiber with at least one Bragg grating (8), and a piezoelectric or piezo-ceramic jacket (31), which device may achieve omnidirectional (360°) imaging. The imaging guide wire of the invention can function as the guide wire for vascular interventions, can enable real time imaging during balloon inflation, and stent deployment, thus will provide clinical information that is not available when catheter based imaging systems are used. The device of the invention may enable shortened total procedure times, including the fluoroscopy time, will also reduce radiation exposure to the patient, and the operator.

    摘要翻译： 本发明是利用光学声学方法进行血管或非血管成像的导丝成像装置，该装置具有直径小于1mm的轮廓。 本发明的超声成像装置包括具有至少一个布拉格光栅（8）的单模光纤和压电或压电陶瓷护套（31），该装置可以实现全向（360°）成像。 本发明的成像引导线可以用作血管干预的导丝，可以在球囊充气和支架展开期间实现实时成像，从而提供当使用基于导管的成像系统时不可用的临床信息。 本发明的装置可以实现缩短的总程序时间，包括透视时间，还可减少对患者和操作者的辐射。

    Extendible stent apparatus
    10.
    发明授权
    Extendible stent apparatus 有权

    公开(公告)号：US06599316B2

    公开(公告)日：2003-07-29

    申请号：US09750372

    申请日：2000-12-27

    申请人： Gil M. Vardi ,  Charles J. Davidson

    发明人： Gil M. Vardi ,  Charles J. Davidson

    IPC分类号： A61F206

    CPC分类号： A61F2/856 ,  A61F2/064 ,  A61F2/07 ,  A61F2/82 ,  A61F2/852 ,  A61F2/91 ,  A61F2/915 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/067 ,  A61F2002/821 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2230/005 ,  A61F2250/006 ,  A61F2250/0098

    摘要： The present invention concerns novel stent apparatuses for use in treating lesions at or near the bifurcation point in bifurcated cardiac, coronary, renal, peripheral vascular, gastrointestinal, pulmonary, urinary and neurovascular vessels and brain vessels. More particularly, the invention concerns a stent apparatus with at least one side opening which may further comprise an extendable stent portion laterally extending from the side opening and at least partly in registry with the wall of the side opening. Devices constructed in accordance with the invention include, singularly or in combination, a main expandable stent comprising at least one substantially circular side opening located between its proximal and distal end openings, which side opening may further comprise an expandable portion extending radially outward from the edges of the side opening; and a branch stent comprising proximal and distal end openings and which may further comprise a contacting portion at its proximal end, and which may optionally be constructed to form either a perpendicular branch or a non-perpendicular branch when inserted through a side opening of the main stent. The stents of the invention are marked with, or at least partially constructed of, a material which is imageable during intraluminal catheterization techniques, most preferably but not limited to ultrasound and x-ray.