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1.发明授权Water soluble macromolecular prodrugs, their preparation and their use as antitumor and antiparasite medicines 失效水溶性大分子前药，其制备及其作为抗肿瘤和抗寄生虫药物的用途
公开(公告)号：US4753984A
公开(公告)日：1988-06-28
申请号：US871883
申请日：1986-06-09
Applicant: Francis Delmotte , Michel Monsigny , Pierre-Jean Lescanne , Francois Daussin
Inventor： Francis Delmotte , Michel Monsigny , Pierre-Jean Lescanne , Francois Daussin
CPC classification number: A61K47/48246 , A61K47/48176 , A61K47/48192 , Y10S930/28
Abstract: A prodrug comprises a polyhydroxylated polyamine to which a drug is linked by the intermediary of a peptidyl group. The prodrug is useful as an antitumor or antiparasite medicine.
Abstract translation: 前药包括多羟基化多胺，其中药物通过肽基的中间连接。 前药可用作抗肿瘤药或抗寄生虫药。
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