公开(公告)号：US08092661B2

公开(公告)日：2012-01-10

申请号：US12084476

申请日：2006-11-02

申请人： Frédéric Canonne ,  Hafsa Korri-Youssoufi ,  Jean-Pierre Mahy ,  Bernard Mandrand ,  Martine Perree-Fauvet

发明人： Frédéric Canonne ,  Hafsa Korri-Youssoufi ,  Jean-Pierre Mahy ,  Bernard Mandrand ,  Martine Perree-Fauvet

IPC分类号： G01N27/26 ,  G01N27/327

CPC分类号： C08G61/124 ,  C07D487/22 ,  G01N27/48

摘要： The invention relates to novel electropolymerisable monomers which are to be polymerised in an aqueous solution and comprise: an electropolymerisable pattern selected from acetylene, pyrrols, thiophenes, indols, anilines, azines, p-phenylene vinylenes, p-phenylenes, pyrenes, furanes, selenophenes, pyrridazines, carbazoles, acrylates, methacrylates and the derivatives thereof, and a metalloporphyrine which is substituted by at least two ionised or ionizable entities in an aqueous solution. The invention also relates to a method for the polymerization of such monomers, to the electroactive probe that can be obtained by the polymerization of such monomers, and to a method for detecting a target ligand in a biological sample using one such electroactive probe.

摘要翻译： 本发明涉及要在水溶液中聚合的新型可电聚合单体，包括：可电聚合图案，其选自乙炔，吡咯，噻吩，吲哚，苯胺，吖嗪，对亚苯基乙烯，对亚苯基，芘，呋喃，硒吩 吡咯嗪，咔唑，丙烯酸酯，甲基丙烯酸酯及其衍生物，以及在水溶液中被至少两个电离或可电离的实体取代的金属卟啉。 本发明还涉及这种单体的聚合方法，可以通过这些单体的聚合获得的电活性探针，以及使用一种这样的电活性探针检测生物样品中的靶配体的方法。

公开(公告)号：US20090314660A1

公开(公告)日：2009-12-24

申请号：US12084476

申请日：2006-11-02

申请人： Frédéric Canonne ,  Hafsa Korri-Youssoufi ,  Jean-Pierre Mahy ,  Bernard Mandrand ,  Martine Perree-Fauvet

发明人： Frédéric Canonne ,  Hafsa Korri-Youssoufi ,  Jean-Pierre Mahy ,  Bernard Mandrand ,  Martine Perree-Fauvet

IPC分类号： G01N27/26 ,  H01B1/12 ,  C07D207/46 ,  C07H21/00 ,  C07K14/00 ,  C07K16/00 ,  C25B3/00

CPC分类号： C08G61/124 ,  C07D487/22 ,  G01N27/48

摘要： The invention relates to novel electropolymerisable monomers which are to be polymerised in an aqueous solution and comprise: an electropolymerisable pattern selected from acetylene, pyrrols, thiophenes, indols, anilines, azines, p-phenylene vinylenes, p-phenylenes, pyrenes, furanes, selenophenes, pyrridazines, carbazoles, acrylates, methacrylates and the derivatives thereof, and a metalloporphyrine which is substituted by at least two ionised or ionisable entities in an aqueous solution. The invention also relates to a method for the polymerisation of such monomers, to the electroactive probe that can be obtained by the polymerisation of such monomers, and to a method for detecting a target ligand in a biological sample using one such electroactive probe.

摘要翻译： 本发明涉及要在水溶液中聚合的新型可电聚合单体，包括：可电聚合图案，其选自乙炔，吡咯，噻吩，吲哚，苯胺，吖嗪，对亚苯基乙烯，对亚苯基，芘，呋喃，硒吩 吡咯嗪，咔唑，丙烯酸酯，甲基丙烯酸酯及其衍生物，以及在水溶液中由至少两个电离或电离实体取代的金属卟啉。 本发明还涉及这种单体的聚合方法，可以通过这些单体的聚合获得的电活性探针，以及使用一种这样的电活性探针检测生物样品中的靶配体的方法。