公开(公告)号：US20240262821A1

公开(公告)日：2024-08-08

申请号：US18557852

申请日：2022-05-06

Applicant: Exscientia Al Limited

Inventor： Peter Ray ,  Anthony Bradley ,  Simon Richards ,  Catarina Santos ,  Jeremy Besnard ,  Jérôme Meneyrol ,  Virginie Suchaud

IPC: C07D471/04 ,  A61K31/437 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/498 ,  A61K31/4985 ,  A61K31/4995 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5383 ,  A61K31/551 ,  C07D487/04 ,  C07D498/04 ,  C07D519/00

CPC classification number: C07D471/04 ,  A61K31/437 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/498 ,  A61K31/4985 ,  A61K31/4995 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5383 ,  A61K31/551 ,  C07D487/04 ,  C07D498/04 ,  C07D519/00

Abstract: Disclosed are compounds, compositions and methods for treating disease, syndromes, conditions and disorders that are affected by the modulation of PKC-theta. Such compounds are represented by Formula I, wherein the variables are defined herein. (I)