-
公开(公告)号:US20240335442A1
公开(公告)日:2024-10-10
申请号:US18294976
申请日:2022-08-02
Inventor: Gabriela BARREIRO , Danilo Pereira De SANT'ANA , Luis Eduardo Reina GAMBA , Carlos Alberto Manssour FRAGA , Eliezer Jesus de Lacerda BARREIRO , Lídia Moreira LIMA
IPC: A61K31/501 , A61P25/02 , C07D241/32
CPC classification number: A61K31/501 , A61P25/02 , C07D241/32
Abstract: N-acylhydrazone compounds that are Nav 1.7 and/or Nav 1.8 inhibitors, including N-acylhydrazone compounds of Formula (I), wherein the substituents R1 to R6 are independently selected from the groups defined in the specification, as well as to the processes for the preparation thereof, compositions comprising at least one of said compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits, and which are applicable in the fields of medicinal chemistry and organic synthesis, as well as in the treatment of pain-related disorders.
-
公开(公告)号:US20240342093A1
公开(公告)日:2024-10-17
申请号:US18744878
申请日:2024-06-17
Applicant: EUROFARMA LABORATÓRIOS S.A.
Inventor: Maurizio BILLI , Matheus Marques COSTA , Emily Fernanda Freire FOLCO
Abstract: The present invention refers to parenterally administered pharmaceutical compositions comprising non-steroidal anti-inflammatory drugs or salts thereof, reconstitutable with specific reconstitution solution and free of buffering agent.
-
公开(公告)号:US20240335420A1
公开(公告)日:2024-10-10
申请号:US18294913
申请日:2022-08-02
Inventor: Gabriela BARREIRO , Danilo Pereira De SANT'ANA , Luis Eduardo Reina GAMBA , Carlos Alberto Manssour FRAGA , Eliezer Jesus de Lacerda BARREIRO , Lídia Moreira LIMA
IPC: A61K31/382 , A61K31/341 , A61K31/4458 , A61K31/451 , A61P25/02 , C07D213/53 , C07D213/73 , C07D213/81 , C07D307/68 , C07D409/12
CPC classification number: A61K31/382 , A61K31/341 , A61K31/4458 , A61K31/451 , A61P25/02 , C07D213/53 , C07D213/73 , C07D213/81 , C07D307/68 , C07D409/12
Abstract: N-Acylhydrazone compounds that are Nav 1.7 and/or Nav 1.8 inhibitors, including N-acylhydrazone compounds of Formula (I), wherein substituents R1 to R4 are independently selected from the groups defined in the specification, as well as to the processes for the preparation thereof, compositions comprising at least one of these compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits, useful in the fields of medicinal chemistry, organic synthesis, as well as in the treatment of pain-related disorders.
-
公开(公告)号:US20230265043A1
公开(公告)日:2023-08-24
申请号:US18006430
申请日:2020-07-27
Applicant: EUROFARMA LABORATÓRIOS S.A.
IPC: C07C211/27 , C07C209/86
CPC classification number: C07C211/27 , C07C209/86 , C07B2200/13
Abstract: The present invention relates to the crystalline form of phentermine hydrochloride monohydrate and processes for obtaining said crystalline form. Phentermine or 2-methyl-1-phenylpropan-2-amine is found in the hydrochloride salt form, being a central nervous system stimulant, used as an appetite suppressant and stimulant in medicaments. The present invention belongs to the fields of chemistry and pharmacy.
-
公开(公告)号:US20220142925A1
公开(公告)日:2022-05-12
申请号:US17435552
申请日:2019-03-01
Applicant: EUROFARMA LABORATÓRIOS S.A.
Inventor: Maurizio BILLI , Matheus Marques COSTA , Emily Fernanda Freire FOLCO
Abstract: The present invention refers to parenterally administered pharmaceutical compositions comprising non-steroidal anti-inflammatory drugs or salts thereof, reconstitutable with specific reconstitution solution and free of buffering agent.
-
-
-
-