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公开(公告)号：US20230125380A1
公开(公告)日：2023-04-27
申请号：US17771777
申请日：2020-11-05
申请人： Dermira, Inc.
发明人： Jamie L. Harden , Hans E.J. Hofland
IPC分类号： A61K31/4439 , A61K9/00 , A61P29/00 , A61P17/00
摘要： This disclosure is directed to use of IRAK4 inhibitors in the treatment of dermatological disorders or conditions characterized by inflammation This disclosure is also directed to pharmaceutical compositions comprising an IRAK4 inhibitor and a pharmaceutically acceptable carrier for topical administration
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公开(公告)号：US09975867B2
公开(公告)日：2018-05-22
申请号：US15015569
申请日：2016-02-04
申请人： Dermira Inc.
IPC分类号： C07D307/68
CPC分类号： C07D307/68
摘要： Disclosed herein are processes for forming 2-furoic acid derivatives represented by Formula (I):
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公开(公告)号：US20160089526A1
公开(公告)日：2016-03-31
申请号：US14869799
申请日：2015-09-29
申请人： Dermira, Inc.
IPC分类号： A61M35/00
CPC分类号： A61M35/003 , A61M2039/226 , A61M2205/10 , A61M2205/276 , A61M2205/581 , A61M2205/583 , A61M2210/04 , B05B11/0037 , B05B11/0038 , B05B11/3059 , B05B11/308 , B05C17/00
摘要： A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.
摘要翻译： 用于分配局部给药的药物的装置具有扩张器，其用于致动泵以释放药物，然后将药物铺展在皮肤上。 吊具耦合到锁，防止在已经分配了许多药物剂量之后启动泵。 可以启动泵以释放不超过每天选择的药物量或致动。
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公开(公告)号：US09006461B2
公开(公告)日：2015-04-14
申请号：US14024480
申请日：2013-09-11
申请人： Dermira, Inc.
发明人： John Allan Statler , Anthony Adrian Shaw , Delphine Caroline Imbert , Jennifer Leigh Nelson , Patricia Andres , Lisa Lynn McQueen , Stephan Xander Mattheus Boerrigter
IPC分类号： C07D207/12 , C07C309/30
CPC分类号： C07D207/12 , C07C309/30
摘要： Salts of glycopyrrolate, including solid forms thereof are herein disclosed. Methods of making glycopyrrolate salts and methods of treating hyperhidrosis with salts of glycopyrrolate are disclosed.
摘要翻译： 本文公开了格隆溴铵盐，包括其固体形式的盐。 公开了制备格隆溴铵盐的方法和用格隆溴铵盐处理多汗症的方法。
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公开(公告)号：US20140371290A1
公开(公告)日：2014-12-18
申请号：US14473537
申请日：2014-08-29
申请人： DERMIRA, INC.
发明人： John Allan STATLER , Anthony Adrian SHAW , Delphine Caroline IMBERT , Jennifer Leigh NELSON , Patricia ANDRES , Lisa Lynn McQUEEN , Stephan Xander Mattheus BOERRIGTER , Jon Gordon SELBO , Mark Christopher ANDRES
IPC分类号： C07C309/30 , C07D207/12
CPC分类号： A61K31/40 , A61K9/0014 , A61K9/08 , A61K9/145 , A61K9/146 , A61K31/10 , A61L15/24 , A61L15/44 , C07C309/30 , C07D207/12 , A61K2300/00 , C08L23/12
摘要： Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
摘要翻译： 公开了格隆溴铵的盐，包括固体形式和制剂如其局部物质。 公开了制备格隆溴铵盐的方法，包括诸如其局部的制剂，以及用格隆溴铵盐处理多汗症的方法，以及其制剂如局部用药。
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公开(公告)号：US20140242122A1
公开(公告)日：2014-08-28
申请号：US14024484
申请日：2013-09-11
申请人： Dermira, Inc.
发明人： John Allan STATLER , Anthony Adrian SHAW , Delphine Caroline IMBERT , Jennifer Leigh NELSON , Patricia ANDRES , Lisa Lynn McQUEEN , Stephan Xander Mattheus BOERRIGTER
IPC分类号： C07D207/12 , C07C309/30
CPC分类号： C07D207/12 , C07C309/30
摘要： Salts of glycopyrrolate, including solid forms thereof are herein disclosed. Methods of making glycopyrrolate salts and methods of treating hyperhidrosis with salts of glycopyrrolate are disclosed.
摘要翻译： 本文公开了格隆溴铵盐，包括其固体形式的盐。 公开了制备格隆溴铵盐的方法和用格隆溴铵盐处理多汗症的方法。
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公开(公告)号：US08558008B2
公开(公告)日：2013-10-15
申请号：US13781390
申请日：2013-02-28
申请人： Dermira, Inc.
发明人： John Allan Statler , Anthony Adrian Shaw , Delphine Caroline Imbert , Jennifer Leigh Nelson , Patricia Andres , Lisa Lynn McQueen , Stephan Xander Mattheus Boerrigter
IPC分类号： C07D207/12
CPC分类号： C07D207/12 , C07C309/30
摘要： Salts of glycopyrrolate, including solid forms thereof are herein disclosed. Methods of making glycopyrrolate salts and methods of treating hyperhidrosis with salts of glycopyrrolate are disclosed.
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公开(公告)号：US10548875B2
公开(公告)日：2020-02-04
申请号：US16235120
申请日：2018-12-28
申请人： Dermira, Inc.
发明人： John Allan Statler , Anthony Adrian Shaw , Delphine Caroline Imbert , Jennifer Leigh Nelson , Patricia Andres , Lisa Lynn McQueen , Stephan Xander Mattheus Boerrigter , Jon Gordon Selbo , Mark Christopher Andres
IPC分类号： C07D207/12 , A61K31/40 , A61K9/00 , A61K9/08 , A61K47/10 , A61K47/12 , A61K47/32 , A61K47/34
摘要： Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
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公开(公告)号：US20190225580A1
公开(公告)日：2019-07-25
申请号：US16370760
申请日：2019-03-29
申请人： Dermira, Inc.
IPC分类号： C07D207/12 , C07C309/30 , C07F11/00 , C07C69/608 , C07C67/08 , C07C309/73 , B01D9/00 , C07C201/12 , C07C303/22 , C07C63/24
摘要： Provided herein are methods for the production of glycopyrronium tosylate and glycopyrronium tosylate compositions. Also provided herein are compositions useful in the production of glycopyrronium tosylate. Additionally provided herein are glycopyrronium tosylate compositions. Glycopyrronium tosylate is useful for the treatment of, among other conditions, hyperhidrosis.
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公开(公告)号：US20180271833A1
公开(公告)日：2018-09-27
申请号：US15996353
申请日：2018-06-01
申请人： Dermira, Inc.
发明人： John Allan STATLER , Anthony Adrian SHAW , Delphine Caroline IMBERT , Jennifer Leigh NELSON , Patricia ANDRES , Lisa Lynn McQUEEN , Stephan Xander Mattheus BOERRIGTER , Jon Gordon SELBO , Mark Christopher ANDRES
IPC分类号： A61K31/40 , A61K47/10 , A61K47/34 , A61K9/00 , A61K9/08 , C07D207/12 , A61K47/12 , A61K47/32
摘要： Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
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