公开(公告)号：US20230340086A1

公开(公告)日：2023-10-26

申请号：US17596652

申请日：2019-06-19

Applicant: Christopher Roland Oelkrug ,  Andreas Bernhard Joachim Schubert

Inventor： Christopher Roland Oelkrug ,  Andreas Bernhard Joachim Schubert

IPC: A61P31/04 ,  C07K16/12 ,  A61K45/06

CPC classification number: C07K16/1203 ,  A61K45/06 ,  A61P31/04 ,  A61K2039/55566

Abstract: Provided herein are antibodies, such as immunoglobulins Y (IgY) antibodies that inhibit beta-lactamase activity, e.g., TEM-1 beta-lactamase, as well as related compositions and methods of use thereof to treat infections by lactam-based antibiotic bacteria that produce beta-lactamase that can degrade antibiotics.