公开(公告)号：US20050152852A1

公开(公告)日：2005-07-14

申请号：US10996427

申请日：2004-11-26

申请人： Eisaku Nishimura ,  Chinami Hirao ,  Tomoko Ohshima ,  Susumu Sato ,  Hiroyuki Inagaki ,  Masanori Kamei ,  Masatoshi Kato ,  Shuichi Hashiizume ,  Nobuko Maeda

发明人： Eisaku Nishimura ,  Chinami Hirao ,  Tomoko Ohshima ,  Susumu Sato ,  Hiroyuki Inagaki ,  Masanori Kamei ,  Masatoshi Kato ,  Shuichi Hashiizume ,  Nobuko Maeda

IPC分类号： A61K8/36 ,  A61K8/97 ,  A61K31/20 ,  A61K31/201 ,  A61K36/185 ,  A61K36/899 ,  A61K45/06 ,  A61Q11/00 ,  A61K7/28 ,  A61K35/78

CPC分类号： A61K8/97 ,  A61K8/361 ,  A61K31/20 ,  A61K31/201 ,  A61K36/185 ,  A61K36/899 ,  A61K45/06 ,  A61Q11/00 ,  A61K2300/00

摘要： It is intended to provide a composition against periodontal bacteria, which has a high safety without showing any side effects and exhibits an excellent effect of killing periodontal bacteria without affecting the growth of nonpathogenic indigenous microorganisms in the oral cavity, and foods, drinks and mouth washers against periodontal bacteria. A composition against periodontal bacteria is blended with a cocoa fraction contained in cacao mass, a hot water-extract of the cocoa fraction, polyphenols originating in the cocoa fraction or free fatty acids originating in the cocoa fraction as the active ingredient. Then the obtained composition against periodontal bacteria is added to foods, drinks, mouth washers or toothpaste. As well as the above-described cocoa fraction, a composition containing cacao mass and/or cocoa is instantly available for the composition against periodontal bacteria. It is preferable that the above-described free fatty acids contain at least one member selected from palmitic acid, stearic acid, oleic acid and linoleic acid.

摘要翻译： 旨在提供一种针对牙周细菌的组合物，其具有高安全性而不显示任何副作用，并且表现出极好的杀死牙周细菌的作用，而不影响口腔内非致病性土着微生物的生长，以及食品，饮料和口腔清洗机 针对牙周细菌。 将针对牙周细菌的组合物与可可块中可可级分，可可级分的热水提取物，源自可可级分的多酚或源自可可级分的游离脂肪酸作为活性成分共混。 然后将获得的针对牙周细菌的组合物加入到食品，饮料，口腔清洁剂或牙膏中。 除了上述可可级分之外，含有可可块和/或可可的组合物可立即获得针对牙周细菌的组合物。 上述游离脂肪酸优选含有选自棕榈酸，硬脂酸，油酸和亚油酸中的至少一种。