公开(公告)号：US06310074B1

公开(公告)日：2001-10-30

申请号：US09573704

申请日：2000-05-18

Applicant: Patrick Depreux ,  Said Yous ,  Gwenael Cheve ,  Gérald Guillaumet ,  Marie-Claude Viaud ,  Carlos Larraya ,  Caroline Bennejean ,  Philippe Delagrange ,  Pierre Renard ,  Carole Descamps-Francois

Inventor： Patrick Depreux ,  Said Yous ,  Gwenael Cheve ,  Gérald Guillaumet ,  Marie-Claude Viaud ,  Carlos Larraya ,  Caroline Bennejean ,  Philippe Delagrange ,  Pierre Renard ,  Carole Descamps-Francois

IPC: A61K3138

CPC classification number: C07D307/79 ,  C07D333/60 ,  C07D471/04

Abstract: The invention relates to compound of formula (I): A—G1—Cy—G2—Cy′—G3—B  (I) wherein: A represents a grouping NR1C(Q)R2, C(Q)NR2R3 or NR1C(Q)NR2R3, B represents a grouping NR1C(Q)R2, NR1C(Q)NR2R3, C(Q)NR2R3, C(Q)OR1, NR1C(Q)OR2 or NR2R3, G1 and G3 represent an optionally substituted alkylene chain, Cy and Cy′, which are different, represent a ring structure or G2 represents a chain and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.

Abstract translation: 本发明涉及式（I）化合物：其中：A表示NR1C（Q）R2，C（Q）NR2R3或NR1C（Q）NR2R3基团，B表示分组NR1C（Q）R2，NR1C（Q）NR2R3 ，C（Q）NR2R3，C（Q）OR1，NR1C（Q）OR2或NR2R3，G1和G3表示任选取代的亚烷基链，Cy和Cy'不同，表示环结构.G2表示含有 这同样可用于治疗或预防褪黑激素障碍。