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公开(公告)号:US20200216421A1
公开(公告)日:2020-07-09
申请号:US16819539
申请日:2020-03-16
发明人: Jirong Peng , Michael John Costanzo , Michael Nicholas Greco , Michael Alan Green , Victoria Lynn Wilde , Don Zhang
IPC分类号: C07D403/04 , A61K45/06 , C07D471/04 , C07D403/14 , C07D401/14 , A61K31/506
摘要: This application discloses novel substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, prodrugs, and compositions thereof, which are useful for the treatment or prevention of diseases or medical conditions mediated by epidermal growth factor receptors (EGFRs), including but not limited to a variety of cancers.
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公开(公告)号:US11414401B2
公开(公告)日:2022-08-16
申请号:US16819539
申请日:2020-03-16
发明人: Jirong Peng , Michael John Costanzo , Michael Nicholas Greco , Michael Alan Green , Victoria Lynn Wilde , Don Zhang
IPC分类号: C07D403/04 , C07D401/14 , C07D471/04 , C07D403/14 , A61K31/506 , A61K45/06 , A61P35/00 , A61P43/00
摘要: This application discloses novel substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, prodrugs, and compositions thereof, which are useful for the treatment or prevention of diseases or medical conditions mediated by epidermal growth factor receptors (EGFRs), including but not limited to a variety of cancers.
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公开(公告)号:US20170362203A1
公开(公告)日:2017-12-21
申请号:US15534838
申请日:2015-12-11
发明人: Jirong Peng , Michael John Costanzo , Michael Nicholas Greco , Michael Alan Green , Victoria Lynn Wilde , Don Zhang
IPC分类号: C07D403/04 , C07D401/14 , A61K31/506 , A61K45/06 , C07D471/04 , C07D403/14
摘要: This application discloses novel substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, prodrugs, and compositions thereof, which are useful for the treatment or prevention of diseases or medical conditions mediated by epidermal growth factor receptors (EGFRs), including but not limited to a variety of cancers.
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公开(公告)号:US10590111B2
公开(公告)日:2020-03-17
申请号:US15534838
申请日:2015-12-11
发明人: Jirong Peng , Michael John Costanzo , Michael Nicholas Greco , Michael Alan Green , Victoria Lynn Wilde , Don Zhang
IPC分类号: C07D403/04 , C07D403/14 , C07D401/14 , C07D471/04 , A61K31/506 , A61K45/06
摘要: This application discloses novel substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, prodrugs, and compositions thereof, which are useful for the treatment or prevention of diseases or medical conditions mediated by epidermal growth factor receptors (EGFRs), including but not limited to a variety of cancers.
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