Radiation-triggered liposomes
    1.
    发明授权

    公开(公告)号:US12208138B2

    公开(公告)日:2025-01-28

    申请号:US16971158

    申请日:2019-02-18

    Inventor: Daniel Fologea

    Abstract: The present disclosure is directed to radiation triggered liposomes and their use in delivery and release of pharmaceutical drugs upon exposure to ionizing radiation. In one embodiment liposomes are provided that comprise cholesterol and sphingolipids modified to comprise reactive groups that are activated by ionizing radiation to form crosslinks with other lipids of the liposome causing the release of the liposomal contents.

    Reconfigurable antenna
    2.
    发明授权

    公开(公告)号:US12113294B2

    公开(公告)日:2024-10-08

    申请号:US17528058

    申请日:2021-11-16

    CPC classification number: H01Q3/24 H01Q3/08 H01Q21/065

    Abstract: A system may include a meta-surface including multiple unit cells arranged along the meta-surface. Structural parameters of each unit cell may vary along the meta-surface. The system may further include at least a first active feed unit directed toward the meta-surface to generate a first beam. The first active feed unit may be configured to move relative to the meta-surface parallel to a 2-dimensional plane. The first beam is steerable by moving the first active feed unit.

    DNA TEMPLATING OF DYES INTO LONG POLYMER DYE AGGREGATES (SUPERDYES) USING MONOMER OR AGGREGATE SUB-UNITS

    公开(公告)号:US20240327643A1

    公开(公告)日:2024-10-03

    申请号:US18625767

    申请日:2024-04-03

    CPC classification number: C09B62/357 G16B50/30

    Abstract: Chemical (e.g., click chemistry), enzymatic- or photo-induced polymerization or other polymerization approaches (e.g., thermally activated) of (1) single dyes (monomer) can be used to produce an extended dye network in which each successive dye is arranged in a head-to-tail arrangement (J-like packing arrangement) of their transition dipole moments or (2) dye aggregate sub-units to achieve polymer branching. Furthermore, various routing patterns are achieved by templating a linear series of dyes onto DNA oligomers of various configurations. Dye aggregate dye sub-unit junctions (e.g., triad, tetrad, pentad, hexad, etc.) are used to achieve polymer branching enable creating various circuit patterns and circuit elements (e.g., optical transistors, gates, etc.). Branched configurations can occur on any surface (e.g., DNA nanostructure, chips substrate, hydrogel, etc.) using DNA (or any similar specific [bio]chemistry).

    Entanglement of excitons by acoustic guiding

    公开(公告)号:US12068085B2

    公开(公告)日:2024-08-20

    申请号:US17447839

    申请日:2021-09-16

    Inventor: Bernard Yurke

    CPC classification number: G21K1/00 H04B10/70

    Abstract: A system is described that exhibits the functionality of a beam-splitter, typically an optical device that splits a beam of light in two. In this case, the beams are acoustic pulses and can lead to the creation of a Wannier-Mott exciton: a bound state of an electron and an electron hole whose attraction to each other is maintained by the electrostatic Coulomb force. This exciton beam-splitter is lossy (i.e., involves the dissipation of electrical or electromagnetic energy). Half of the time the exciton is radiated away. Nevertheless, if the exciton is not lost, the exciton is now in a superposition of two states that can be well separated in position. Four such beam-splitters can be used to make an exciton interferometer that uses the interference patterns from the interacting acoustic pulses to extract information.

    RIGID LINKERS TO PROMOTE J-PACKING AND ENHANCE Kr

    公开(公告)号:US20240034883A1

    公开(公告)日:2024-02-01

    申请号:US18361055

    申请日:2023-07-28

    CPC classification number: C09B47/00 C12Q1/6816

    Abstract: Dye aggregates that are templated to deoxyribonucleic acid (DNA) can exhibit different packing arrangements and, as an optically active medium, spectral properties of interest. Steric effects and properties of the linker that tethers the dye to a DNA scaffold (a simple nucleotide oligomer or more complex architectures) can used to fine tune the packing arrangement of the dyes to obtain desirable spectral properties. To gain access to J-aggregates (head-to-tail packing arrangement) as a source of fluorescent materials, the present disclosure is directed to two strategies that utilize rigid linkers to promote J-packing. Devices and methods of use also are disclosed herein.

    RECONFIGURABLE ANTENNA
    8.
    发明申请

    公开(公告)号:US20220158342A1

    公开(公告)日:2022-05-19

    申请号:US17528058

    申请日:2021-11-16

    Abstract: A system may include a meta-surface including multiple unit cells arranged along the meta-surface. Structural parameters of each unit cell may vary along the meta-surface. The system may further include at least a first active feed unit directed toward the meta-surface to generate a first beam. The first active feed unit may be configured to move relative to the meta-surface parallel to a 2-dimensional plane. The first beam is steerable by moving the first active feed unit.

    ENTANGLEMENT OF EXCITONS BY ACOUSTIC GUIDING

    公开(公告)号:US20220084710A1

    公开(公告)日:2022-03-17

    申请号:US17447839

    申请日:2021-09-16

    Inventor: Bernard Yurke

    Abstract: A system is described that exhibits the functionality of a beam-splitter, typically an optical device that splits a beam of light in two. In this case, the beams are acoustic pulses and can lead to the creation of a Wannier-Mott exciton: a bound state of an electron and an electron hole whose attraction to each other is maintained by the electrostatic Coulomb force. This exciton beam-splitter is lossy (i.e., involves the dissipation of electrical or electromagnetic energy). Half of the time the exciton is radiated away. Nevertheless, if the exciton is not lost, the exciton is now in a superposition of two states that can be well separated in position. Four such beam-splitters can be used to make an exciton interferometer that uses the interference patterns from the interacting acoustic pulses to extract information.

Patent Agency Ranking