公开(公告)号：US20070123591A1

公开(公告)日：2007-05-31

申请号：US11583953

申请日：2006-10-20

申请人： Nagarajan Kuppuswamy ,  Sivaramakrishnan Hariharan ,  Venkatachalam Sankar Iyer ,  Suresh Babu Balakrishnan ,  Gopalakrishnan Krishnamurthi ,  Ananda Kuppanna ,  Muruga Poopati Raja Karuppiah ,  Balaram Padmanabhan ,  Aravinda Subrayashastry ,  Gouriamma Vasudev Prema ,  Shamala Narayanaswamy

发明人： Nagarajan Kuppuswamy ,  Sivaramakrishnan Hariharan ,  Venkatachalam Sankar Iyer ,  Suresh Babu Balakrishnan ,  Gopalakrishnan Krishnamurthi ,  Ananda Kuppanna ,  Muruga Poopati Raja Karuppiah ,  Balaram Padmanabhan ,  Aravinda Subrayashastry ,  Gouriamma Vasudev Prema ,  Shamala Narayanaswamy

IPC分类号： A61K31/195 ,  C07C229/12

CPC分类号： C07C229/28 ,  C07C233/08 ,  C07C2601/14

摘要： The present invention relates to compounds trans (E) and cis (Z) stereoisomers of 4-t-butyl gabapentin of formula (11) and (12) and a process for the preparation of the said stereoisomers.

摘要翻译： 本发明涉及式（11）和（12）的4-叔丁基加巴喷丁的反式（E）和顺式（Z）立体异构体的制备方法和所述立体异构体的制备方法。

公开(公告)号：US07632864B2

公开(公告)日：2009-12-15

申请号：US11583953

申请日：2006-10-20

申请人： Nagarajan Kuppuswamy ,  Sivaramakrishnan Hariharan ,  Venkatachalam Sankar Iyer ,  Suresh Babu Balakrishnan ,  Gopalakrishnan Krishnamurthi ,  Ananda Kuppanna ,  Muruga Poopati Raja Karuppiah ,  Balaram Padmanabhan ,  Aravinda Subrayashastry ,  Gouriamma Vasudev Prema ,  Shamala Narayanaswamy

发明人： Nagarajan Kuppuswamy ,  Sivaramakrishnan Hariharan ,  Venkatachalam Sankar Iyer ,  Suresh Babu Balakrishnan ,  Gopalakrishnan Krishnamurthi ,  Ananda Kuppanna ,  Muruga Poopati Raja Karuppiah ,  Balaram Padmanabhan ,  Aravinda Subrayashastry ,  Gouriamma Vasudev Prema ,  Shamala Narayanaswamy

IPC分类号： A61K31/195 ,  C07C229/00

CPC分类号： C07C229/28 ,  C07C233/08 ,  C07C2601/14

摘要： The present invention relates to compounds trans (E) and cis (Z) stereoisomers of 4-t-butyl gabapentin of formula (11) and (12) and a process for the preparation of the said stereoisomers.

摘要翻译： 本发明涉及式（11）和（12）的4-叔丁基加巴喷丁的反式（E）和顺式（Z）立体异构体的制备方法和所述立体异构体的制备方法。

公开(公告)号：US20050209332A1

公开(公告)日：2005-09-22

申请号：US11079481

申请日：2005-03-15

申请人： Nagarajan Kuppuswamy ,  Sivaramakrishnan Hariharan ,  Venkatachalam Iyer ,  Suresh Balakrishnan ,  Gopalakrishnan Krishnamurthi ,  Ananda Kuppanna ,  Muruga Karuppiah ,  Balaram Padmanabhan ,  Aravinda Subrayashastry ,  Gouriamma Prema ,  Shamala Narayanaswamy

发明人： Nagarajan Kuppuswamy ,  Sivaramakrishnan Hariharan ,  Venkatachalam Iyer ,  Suresh Balakrishnan ,  Gopalakrishnan Krishnamurthi ,  Ananda Kuppanna ,  Muruga Karuppiah ,  Balaram Padmanabhan ,  Aravinda Subrayashastry ,  Gouriamma Prema ,  Shamala Narayanaswamy

IPC分类号： A61K31/195

CPC分类号： C07C229/28 ,  C07C233/08 ,  C07C2601/14

摘要： The present invention relates to compounds cis (Z) and trans (E) stereoisomers of 4-t-butylgabapentin of formula (11) and (12) and a process for the preparation of the said stereoisomers.

摘要翻译： 本发明涉及式（11）和（12）的4-叔丁基加巴喷丁的顺式（Z）和反（E）立体异构体的化合物和制备所述立体异构体的方法。