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1.发明公开公开(公告)号：US20240050317A1
公开(公告)日：2024-02-15
申请号：US18489074
申请日：2023-10-18
发明人： Alexander Mark Schobel , Keith Kendall , Dan Barber , Theresa Wood , Peter Boyd , John Maxwell
CPC分类号： A61J3/00 , G16H20/17 , G16H20/13 , A61J2200/70 , A61J2205/10 , A61J2205/20
摘要： Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
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公开(公告)号：US20220347117A1
公开(公告)日：2022-11-03
申请号：US17691107
申请日：2022-03-09
摘要： Self-supporting film unit dosage forms for oral transmucosal delivery are disclosed herein containing an active. These film dosage forms for oral transmucosal delivery have a substantially equivalent pharmacokinetic profile to dosage forms administered by another route or in another dosage form (e.g., tablet, patch) and yet have a different amount of active contained therein.
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公开(公告)号：US11191737B2
公开(公告)日：2021-12-07
申请号：US15587364
申请日：2017-05-04
IPC分类号： A61K31/137 , A61K9/00 , A61J1/03 , A61J1/05 , A61J7/00 , A61K9/70 , A61K31/085 , A61K36/61 , A61K47/10 , A61K47/12 , A61K47/22 , A61K47/38
摘要： Pharmaceutical compositions having enhanced active component permeation properties are described.
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4.发明授权公开(公告)号：US10888499B2
公开(公告)日：2021-01-12
申请号：US16505327
申请日：2019-07-08
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
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公开(公告)号：US10821074B2
公开(公告)日：2020-11-03
申请号：US16048243
申请日：2018-07-28
发明人： Garry L. Myers , Samuel D. Hilbert , Bill J. Boone , B. Arlie Bogue , Pradeep Sanghvi , Madhusudan Hariharan
IPC分类号： A61K9/00 , A61K9/70 , A61K47/10 , A61K31/485 , A61K47/12
摘要： The present invention relates to products and methods for treatment of various symptoms in a patient, including treatment of pain suffered by a patient. The invention more particularly relates to self-supporting dosage forms which provide an active agent while providing sufficient buccal adhesion of the dosage form. Further, the present invention provides a dosage form which is useful in reducing the likelihood of diversion abuse of the active agent.
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6.发明申请公开(公告)号：US20200155414A1
公开(公告)日：2020-05-21
申请号：US16505327
申请日：2019-07-08
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
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公开(公告)号：US20200146997A1
公开(公告)日：2020-05-14
申请号：US16743766
申请日：2020-01-15
IPC分类号： A61K9/70 , A23P20/20 , A23L27/00 , A23L33/00 , A23L23/10 , A23F5/36 , A23L2/395 , A61K8/02 , A61K8/73 , A61K8/86 , A61K9/00 , A61Q11/00 , A61Q19/00 , C08J5/18 , F26B13/20 , A61K8/34 , A61K8/37 , A61K8/49 , A61K8/81 , A61K8/891 , A61K31/192 , A61K31/4545 , A61K47/26 , A61K47/34 , A61K47/38
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film. The invention further relates to edible multi-layer films that dissolve in water. In particular, the edible multi-layer films have a first water-soluble film layer and one or more additional water-soluble film layers in at least partial face-to-face engagement with the first film layer.
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8.发明申请公开(公告)号：US20190388302A1
公开(公告)日：2019-12-26
申请号：US16447107
申请日：2019-06-20
发明人： Alexander Mark Schobel , Keith Kendall , Dan Barber , Theresa Wood , Peter Boyd , John Maxwell
摘要： Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
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9.发明申请公开(公告)号：US20190060172A1
公开(公告)日：2019-02-28
申请号：US15936241
申请日：2018-03-26
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
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公开(公告)号：US20240148673A1
公开(公告)日：2024-05-09
申请号：US18413556
申请日：2024-01-16
IPC分类号： A61K31/137 , A61K9/00 , A61K9/70 , A61K31/7034 , A61K47/38
CPC分类号： A61K31/137 , A61K9/006 , A61K9/7007 , A61K31/7034 , A61K47/38
摘要： Pharmaceutical compositions of epinephrine and its prodrugs are described, the prodrugs having a half-life of less than one minute, and the compositions having enhanced active component permeation properties are described.
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