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公开(公告)号:US06225457B1
公开(公告)日:2001-05-01
申请号:US09305001
申请日:1999-05-04
申请人: Sanjoy Biswas , James Raymond Brown , Martin K R Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin K R Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C07H2104
CPC分类号: C07K14/3156 , A61K38/00 , A61K48/00 , C07K2319/00
摘要: The invention provides murF2 polypeptides and polynucleotides encoding murF2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murF2 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码murF2多肽的murF2多肽和多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用murF2多肽筛选抗菌化合物的方法。
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公开(公告)号:US06399343B1
公开(公告)日:2002-06-04
申请号:US09574912
申请日:2000-05-19
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
IPC分类号: C12N900
CPC分类号: C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要: The invention provides infB polypeptides and polynucleotides encoding infB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing in polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供编码infB多肽的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了在多肽中利用筛选抗菌化合物的方法。
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公开(公告)号:US06350600B1
公开(公告)日:2002-02-26
申请号:US09627769
申请日:2000-07-28
申请人: Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N900
CPC分类号: C12N9/1007 , A61K38/00 , A61K39/00 , A61K48/00
摘要: The invention provides trmA methyl transferase (trmD) polypeptides and polynucleotides encoding trmD polypeptides and methods for producing such polypeptides by recominant techniques from strepococcus pneumoniae. Also provided are methods for utilizing polypepides to screen for antibacterial compounds.
摘要翻译: 本发明提供trmA甲基转移酶(trmD)多肽和编码trmD多肽的多核苷酸以及通过来自肺炎链球菌的重组技术产生此类多肽的方法。 还提供了利用多肽来筛选抗菌化合物的方法。
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公开(公告)号:US06245542B1
公开(公告)日:2001-06-12
申请号:US09306276
申请日:1999-05-06
申请人: Sanjoy Biswas , Alexander Bryant , James Raymond Brown , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Stephanie Van Horn , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , Alexander Bryant , James Raymond Brown , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Stephanie Van Horn , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N910
CPC分类号: C12N9/1007 , A61K38/00
摘要: The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了yfjO多肽和编码yfjO多肽的多核苷酸,以及通过重组技术产生此类多肽的方法。 还提供了利用yfj多肽筛选抗菌化合物的方法。
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公开(公告)号:US06251631B1
公开(公告)日:2001-06-26
申请号:US09250677
申请日:1999-02-16
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Alison Francis Chalker , Karen Anne Ingraham , Christopher Michael Traini , Patrick Vernon Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Alison Francis Chalker , Karen Anne Ingraham , Christopher Michael Traini , Patrick Vernon Warren , Magdalena Zalacain
IPC分类号: C07K14315
CPC分类号: C07K14/3156 , A61K38/00 , A61K39/00 , C12N9/00
摘要: The invention provides nadE polypeptides and polynucleotides encoding nadE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nadE polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了nadE多肽和编码nadE多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用nadE多肽筛选抗菌化合物的方法。
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公开(公告)号:US06228625B1
公开(公告)日:2001-05-08
申请号:US09273686
申请日:1999-03-22
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N900
CPC分类号: C12Q1/6876 , A61K38/00 , C07K14/3156
摘要: The invention provides metK polypeptides and polynucleotides encoding metK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metK polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了metK多肽和编码metK多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用metK多肽来筛选抗菌化合物的方法。
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公开(公告)号:US06346395B1
公开(公告)日:2002-02-12
申请号:US09239052
申请日:1999-01-27
申请人: Alison Francis Chalker , Christine Debouck , David John Holmes , Karen Anne Ingraham , Deborah Dee Jaworski , Anna Lisa Kosmatka , Damien McDevitt , Jeffrey Mooney , Stewart C Pearson , Chi Yong So , Nicola Gail Wallis , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人: Alison Francis Chalker , Christine Debouck , David John Holmes , Karen Anne Ingraham , Deborah Dee Jaworski , Anna Lisa Kosmatka , Damien McDevitt , Jeffrey Mooney , Stewart C Pearson , Chi Yong So , Nicola Gail Wallis , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号: C12D2106
CPC分类号: C12N9/0006 , A61K38/00 , C12Y101/011
摘要: The invention provides FabG polypeptides and polynucleotides encoding FabG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabG polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了FabG多肽和编码FabG多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用FabG多肽筛选抗菌化合物的方法。
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公开(公告)号:US06326172B1
公开(公告)日:2001-12-04
申请号:US09433994
申请日:1999-11-04
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Patrick Vernon Warren , Stephanie Van Horn , Magdalena Zalacain
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Patrick Vernon Warren , Stephanie Van Horn , Magdalena Zalacain
IPC分类号: C12N1509
CPC分类号: C07K14/3156 , A61K38/00 , A61K48/00 , C07K14/315
摘要: The invention provides ytgP polypeptides and polynucleotides encoding ytgP polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ytgP polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ytgP多肽和编码ytgP多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ytgP多肽筛选抗菌化合物的方法。
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公开(公告)号:US06268177B1
公开(公告)日:2001-07-31
申请号:US09285576
申请日:1999-04-02
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N1500
CPC分类号: C12N9/1077
摘要: The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了ndp多肽和编码ndp多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ndp多肽筛选抗菌化合物的方法。
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公开(公告)号:US06245891B1
公开(公告)日:2001-06-12
申请号:US09285515
申请日:1999-04-02
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C07K100
CPC分类号: C07K14/3156
摘要: The invention provides nusB polypeptides and polynucleotides encoding nusB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nusB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码nusB多肽的nusB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用nusB多肽筛选抗菌化合物的方法。
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