公开(公告)号：US06288088B1

公开(公告)日：2001-09-11

申请号：US09701544

申请日：2000-11-30

Applicant: Yasuyuki Kando ,  Makota Noguchi ,  Akayama Atsuo ,  Shinichi Masada ,  Toshiyuki Kiji

Inventor： Yasuyuki Kando ,  Makota Noguchi ,  Akayama Atsuo ,  Shinichi Masada ,  Toshiyuki Kiji

IPC: A61K314245

CPC classification number: C07D413/04 ,  A01N47/02 ,  A01N47/14 ,  A01N47/38 ,  C07D413/14

Abstract: The present invention relates to a compound of the formula [I]: wherein R1 is C1-6 alkyl or C1-6 haloalkyl; n is 0, 1 or 2; X is (1) group of —NR2R3 wherein R2 and R3 independently represent (i) hydrogen or (ii) C1-6 alkyl which may optionally be substituted with pyridyl, (2) group of —N═CHOR4 wherein R4 represents C1-6 alkyl, (3) group of —N═CHNR6R7 wherein R6 and R7 independently represent (i) hydrogen or (ii) C1-6 alkyl, (4) group of —N═CHAr wherein Ar represents phenyl which may optionally be substituted with substituents selected from the group consisting of hydroxy and C1-3 alkoxy, or (5) pyrrolyl; R5 is optionally substituted alkyl or optionally substituted acyl; R8 is (1) halogen, (2) C1-6 haloalkyl, (3) C1-6 haloalkoxy or (4) phenyl which may optionally be substituted with C1-6 haloalkyl; A is (1) nitrogen atom or (2) group of wherein R9 is chlorine atom or cyano; and B is nitrogen atom or or a salt thereof. The compounds [I] or their salts have excellent insecticidal activities and less toxicity against fishes. Therefore, the agrochemical compositions containing the compound [I] or a salt thereof can protect crops, etc. from harmful pests so as to contribute to an agricultural success.

Abstract translation: 本发明涉及式[I]的化合物：其中R 1是C 1-6烷基或C 1-6卤代烷基; n为0,1或2; X是（1）-NR2R3基团，其中R2和R3独立地表示（i）氢或（ii）可任选被吡啶基取代的C 1-6烷基，（2）-N = CHOR 4基团，其中R 4表示C 1-6 烷基，（3）-N = CHNR 6 R 7基团，其中R 6和R 7独立地表示（i）氢或（ii）C 1-6烷基，（4）-N = CHAr基团，其中Ar表示可以被取代基取代的苯基 选自羟基和C 1-3烷氧基，或（5）吡咯基; R5是任选取代的烷基或任选取代的酰基; R 8是（1）卤素，（2）C 1-6卤代烷基，（3）C 1-6卤代烷氧基或（4）可任选地被C 1-6卤代烷基取代的苯基; A是 （1）氮原子或（2）其中R9为氯原子或氰基; 并且B是氮原子或其盐。化合物[I]或其盐具有优良的杀虫活性和对鱼的毒性较小。 因此，含有化合物[I]或其盐的农药组合物可以保护作物等不受有害害虫的影响，从而有助于农业的成功。