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公开(公告)号:US20230137333A1
公开(公告)日:2023-05-04
申请号:US17906213
申请日:2020-11-18
Applicant: Lepu Medical Technology (Beijing) Co., Ltd
Inventor: Hongdai Sun , Jun Cao
Abstract: A blood pressure prediction method includes acquiring a data source identifier and original data; performing a data preprocessing operation on the original data; performing normalized filtering on a first-class PPG original signal to generate a standard PPG data sequence; when the data source identifier is a first-class PPG original signal identifier, performing baseline drift removal and normalized filtering on a second-class PPG original signal to generate a standard PPG data sequence; when the data source identifier is a second-class PPG video identifier, performing video quality detection and normalized signal conversion on third-class video data to generate a standard PPG data sequence; obtaining a CNN model identifier; and selecting a corresponding CNN model to predict blood pressure on the standard PPG data sequence according to the data source identifier and/or the CNN model identifier.
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公开(公告)号:US20240325610A1
公开(公告)日:2024-10-03
申请号:US18246449
申请日:2022-06-10
Applicant: LEPU MEDICAL TECHNOLOGY (BEIJING) CO., LTD.
Inventor: Yangyang LIU , Lixiao ZHAO , Cuijie MA , Yi ZHANG , Xiaojun HU
CPC classification number: A61L29/16 , A61L29/085 , A61L2300/21 , A61L2300/22 , A61L2300/232 , A61L2300/30 , A61L2300/404 , A61L2300/41 , A61L2300/416 , A61L2300/426 , A61L2300/434 , A61L2400/12 , A61L2420/02 , A61L2420/06
Abstract: The present invention relates to the technical field of medical devices, in particular to a drug coating, a drug-coated balloon and a preparation method thereof. The drug coating comprises a drug active coating and a positively-charged hydrophobic modified layer which are sequentially attached to the surface of a substrate. By providing the positively charged hydrophobic modified layer comprising the positively-charged modified substance and the hydrophobic substance, the entire surface of the drug coating is given positive electric charge and hydrophobic property. Such positive electric charge characteristics make the drug coating can be strongly combined with the negatively-charged inner wall of blood vessels, so that the drug coating can be permanently adsorbed on the inner wall of blood vessels. The combination of positive electric charge characteristics and hydrophobic property can effectively resist the influence of blood flow on the erosion of drug coating during transportation.
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公开(公告)号:US11690717B2
公开(公告)日:2023-07-04
申请号:US17056580
申请日:2020-03-30
Applicant: LEPU MEDICAL TECHNOLOGY (BEIJING) CO., LTD.
Inventor: Yang Zhao , Xiaojian Liu , Yuxin Zhang , Zhongjie Pu
IPC: A61F2/24 , A61B17/122 , A61B17/128
CPC classification number: A61F2/2436 , A61B17/1222 , A61B17/1285 , A61F2210/0014 , A61F2220/0016 , A61F2220/0075 , A61F2250/001
Abstract: The application relates to a heart valve clamp, comprises a fixed arm mechanism, a clamping arm mechanism, and a driving mechanism. The fixed arm mechanism comprises a fixed arm body and at least two fixed arms, extending outward from the fixed arm body, and integrally formed with the fixed arm body. The clamping arm mechanism comprises a clamping arm body connected to a bottom of the fixed arm body, and at least two clamping arms extending outward from the clamping arm bodies and integrally formed with the clamping arm body; and the driving mechanism comprises a second driving assembly that drives the fixed arm and the clamping arm to open or close. The fixed arm mechanism and the clamping arm mechanism of the entire heart valve clamp respectively forms an integral form, which can avoid the risk of the fixed arm or the clamping arm being disengaged, the stability of the whole structure is better. The fixed arm and the clamping arm clamp the valve leaflets under three-dimensional ultrasound and angiography navigation, so that the regurgitation area is reduced, which is capable of treating mitral or tricuspid regurgitation while keeping heat beating.
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公开(公告)号:US20230071469A1
公开(公告)日:2023-03-09
申请号:US17904688
申请日:2020-11-18
Applicant: Lepu Medical Technology (Beijing) Co., Ltd
Abstract: A method for generating PPG signals may include sequentially performing single-frame red and green channel data calculation on all skin surface video data frame images of a frame image sequence of skin surface video data according to preset red and green light pixel threshold ranges to generate first red and green light signals; performing signal band-pass filtering preprocessing on the first red and green light signals to generate second red and green light digital signals; obtaining a preset signal determination identifier; determining whether to perform signal maximum frequency difference determination on the second red light signal and the second green light signal, and generating a first determination result; when the first determination result is an up-to-standard signal identifier, performing signal-to-noise ratio determination on the second red and/or green light signal to generate a second determination result; and when the second determination result is the up-to-standard signal identifier, generating a PPG signal.
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公开(公告)号:US20230380893A1
公开(公告)日:2023-11-30
申请号:US18007000
申请日:2022-08-04
Applicant: Lepu Medical Technology (Beijing) Co., Ltd.
Inventor: Lei WANG , Yishou DING , Yuxin ZHANG , Zhongjie PU , Tao HE , Qi LIU
IPC: A61B18/14
CPC classification number: A61B18/1492 , A61B2018/00577
Abstract: A radiofrequency ablation device comprising an electrode, a balloon and a delivery tube; the electrode is in a shape of a mesh which has a contracted state that shrinks together under restriction and an expanded state that automatically expands outward without restriction, and is connected to an external electrical connector through an electrode lead; the balloon is located at the inner side of the electrode, and pushes against the electrode when it is in an expanded state; the delivery tube comprises an outer tube and an inner tube, the electrode lead is located between the electrical outer tube and the inner tube, and the delivery tube further comprises a balloon catheter communicating with one end of the balloon, which is located at the inner side of the inner tube and has a gap with the inner tube.
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公开(公告)号:US20220409077A1
公开(公告)日:2022-12-29
申请号:US17904692
申请日:2020-11-18
Applicant: Lepu Medical Technology (Beijing) Co., Ltd
Abstract: A method for generating PPG signals may include photographing a skin surface to generate fragment video data; extracting fragment frame images from the fragment video data; performing image quality detection on the fragment frame images to generate an image quality detection result; when the image quality detection result indicates an up-to-standard image, performing one-dimensional red and green light signal extraction on the fragment frame images to generate first red and green signals; performing signal band-pass filtering preprocessing on the first red and green signals to generate second red and green signals; performing maximum frequency difference determination on the second red and green signals to generate a first determination result; when the first determination result indicates an up-to-standard signal, performing signal-to-noise ratio determination on the second red and green signals to generate a second determination result; and when the second determination result indicates an up-to-standard signal, generating a first PPG signal.
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公开(公告)号:US20160345943A1
公开(公告)日:2016-12-01
申请号:US15117752
申请日:2014-04-30
Applicant: LEPU MEDICAL TECHNOLOGY (BEIJING) CO., LTD
IPC: A61B17/00
CPC classification number: A61B17/0057 , A61B2017/00004 , A61B2017/00243 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/00986 , A61B2017/00991
Abstract: A medical closure system comprises a closure stent (100) and a delivery device (200); the closure stent (100) comprises a stent outer layer (1), a film (3) disposed on the stent outer layer (1), and a mandrel (8) passing through the stent outer layer (1); the distal end of the mandrel (8) is fixedly connected to the distal end of the stent outer layer (1); the closure stent (100) is made of a degradable polymer; the delivery device (200) comprises an external push tube (11) and an internal push rod (10) installed in the external push tube (11); the external push tube (11) and the internal push rod (10) are movable relative to each other in an axial direction; the external push tube (11) is movably connected to the proximal end of the stent outer layer (1); and the internal push rod (10) is movably connected to the proximal end of the mandrel (8). The medical closure system can automatically degrade after being implanted into a human body, thus eliminating the hidden risk of a side effect caused by residue of the closure stem left in the human body.
Abstract translation: 医疗闭合系统包括闭合支架(100)和输送装置(200); 闭合支架(100)包括支架外层(1),设置在支架外层(1)上的膜(3)和穿过支架外层(1)的心轴(8); 心轴(8)的远端固定地连接到支架外层(1)的远端; 闭合支架(100)由可降解聚合物制成; 输送装置(200)包括安装在外部推管(11)中的外部推管(11)和内部推杆(10)。 外推头(11)和内推杆(10)可沿轴向相对移动; 所述外部推管(11)可移动地连接到支架外层(1)的近端; 并且内部推杆(10)可移动地连接到心轴(8)的近端。 医疗闭合系统在植入人体后会自动降解,从而消除了由人体残留物引起的副作用隐藏的隐患。
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公开(公告)号:US20210196373A1
公开(公告)日:2021-07-01
申请号:US17056656
申请日:2019-12-30
Applicant: LEPU MEDICAL TECHNOLOGY (BEIJING) CO., LTD.
Inventor: Tao HE , Yishou DING , Xibo ZHANG , Xiangyi LI , Jie CAI , Liyun LIU , Ping HE , Hao CHEN , Yuxin ZHANG , Zhongjie PU
IPC: A61B18/14
Abstract: The application relates to a reaming type non-implanted atrial shunt device comprising a catheter component (2), a radio frequency component (1) disposed on an end of the catheter component (2) extending into a human body, and a radio frequency ablation instrument (4) disposed on the other end of the catheter component (2) and connected with the radio frequency component (1), wherein after the radio frequency component (1) extends into a puncture hole, the radio frequency ablation instrument (4) releases a radio frequency energy, and the radio frequency component (1) ablates a wall of the puncture hole. The radio frequency component (1) is delivered to the position of the puncture hole. When the radio frequency ablation instrument (4) releases energy, the radio frequency component (1) causes the hole wall tissue to generate heat and ablate the atrial septum at a target position to form a hole with fixed size, thereby achieving the purpose of creating a hole. Using radio frequency components (1) to create a hole through radio frequency make the hole not easy to reclose. The hole can effectively drain the left atrium blood into the right atrium, reduce pressure of the left atrium, thereby achieving the purpose of treatment.
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公开(公告)号:US20130184746A1
公开(公告)日:2013-07-18
申请号:US13809883
申请日:2011-07-14
Applicant: Wanbing Liu , Shuxin Li
Inventor: Wanbing Liu , Shuxin Li
IPC: A61B17/135
CPC classification number: A61B17/135 , A61M5/34 , A61M39/26 , A61M2039/1094
Abstract: An inflation-deflation device for tourniquet comprising: a barrel (11) and a plunger (12) fitting tightly within the barrel (11). A connecting rod (13) is fixed at one end of the plunger (12). The barrel (11) is fixedly connected at its bottom to a short tube (10). The short tube (10) is connected to the interior space of the barrel (11). The connecting rod (13) having a cruciform cross-section structure, a baffle (16) is perpendicularly fixed to the two sides opposite each other from the central axis of the structure. Connected on the barrel (11) is a clasp (15), the clasp (15) is fixedly connected to the barrel (11) and extends into the interior surface of the barrel (11). The inflation-deflation device has a distinctively designed inflation hole connection tip, to prevent confusion with a standard Luer connection of an ordinary liquid syringe, and also has a distinctively designed deflation limit, to control effectively the volume of gas discharged in a single deflation, and to prevent mishandling.
Abstract translation: 一种用于止血带的通气放气装置,包括:筒体(11)和紧密配合在筒体(11)内的柱塞(12)。 连杆(13)固定在柱塞(12)的一端。 桶(11)在其底部固定地连接到短管(10)。 短管(10)连接到枪管(11)的内部空间。 具有十字形横截面结构的连杆(13),挡板(16)垂直地固定到与结构的中心轴线相对的两侧。 连接在筒体(11)上的是钩扣(15),该扣钩(15)固定地连接到枪管(11)并延伸到枪管(11)的内表面。 充气 - 充气装置具有独特设计的充气孔连接尖端,以防止与普通液体注射器的标准Luer连接混淆,并且还具有独特设计的通气限制,以有效地控制在单次通气中排出的气体的体积, 并防止误操作。
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公开(公告)号:US20230397887A1
公开(公告)日:2023-12-14
申请号:US18248770
申请日:2021-04-19
Applicant: Lepu Medical Technology (Beijing) Co., Ltd.
Inventor: Jun Cao , Hongdai Sun , Zhe Li
CPC classification number: A61B5/7264 , A61B5/02416 , A61B5/021 , A61B5/7275
Abstract: A method for predicting blood pressure by fusing calibrated photoplethysmography (PPG) signal data includes obtaining real-time PPG signal data, calibrated PPG signal data, calibrated diastolic blood pressure data, and systolic blood pressure data; using a CNN+ANN model to calculate the relative blood pressure data, and generating an ANN output tensor, according to the calibrated diastolic blood pressure and systolic blood pressure data, and the ANN output tensor, performing blood pressure data calculation and generating a blood pressure tensor; if the predicted type information is a first type, performing a mean value calculation according to the blood pressure tensor, and generating diastolic blood pressure prediction data and systolic blood pressure prediction data; if the predicted type information is a second type, performing data extraction processing on the blood pressure tensor, and generating a diastolic blood pressure prediction data sequence and a systolic blood pressure prediction data sequence.
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