METHODS OF ADMINISTERING DRUGS IN AN IMPLANTABLE MULTI-CHAMBER PUMP
    4.
    发明申请
    METHODS OF ADMINISTERING DRUGS IN AN IMPLANTABLE MULTI-CHAMBER PUMP 审中-公开
    在可植入的多室泵中施用药物的方法

    公开(公告)号:US20140296830A1

    公开(公告)日:2014-10-02

    申请号:US14228192

    申请日:2014-03-27

    IPC分类号: A61M5/14 A61M5/142

    摘要: One embodiment of the present invention is a method for reducing pain using a multi chamber pump to separately administer multiple drugs. For example, one chamber may contain an omega conopeptide, such as ziconotide, and the other chamber or chambers may contain one or more other drugs, which may include of morphine, hydromorphone, fentanyl, sufentanil, bupivacaine, baclofen, clonidine, and buprenorphine, or their pharmaceutically acceptable salts thereof. Other applications of the present invention include methods for treating severe chronic pain due to cancer, failed back syndrome, CRPS, neuropathic pain, mixed neuropathic and nociceptive pain.

    摘要翻译: 本发明的一个实施方案是使用多室泵分别施用多种药物来减轻疼痛的方法。 例如,一个室可以含有ω-肽,例如齐考诺肽,另一个室或室可以含有一种或多种其他药物,其可以包括吗啡,氢吗啡酮,芬太尼,舒芬太尼,布比卡因,巴氯芬,可乐定和丁丙诺啡, 或其药学上可接受的盐。 本发明的其它应用包括用于治疗由于癌症,失败后综合征,CRPS,神经性疼痛,混合型神经病变和伤害性疼痛引起的严重慢性疼痛的方法。

    SENSITIVE DRUG DISTRIBUTION SYSTEM AND METHOD
    6.
    发明申请
    SENSITIVE DRUG DISTRIBUTION SYSTEM AND METHOD 审中-公开
    敏感性药物分配系统和方法

    公开(公告)号:US20140207481A1

    公开(公告)日:2014-07-24

    申请号:US14219941

    申请日:2014-03-19

    IPC分类号: G06F19/00

    摘要: A drug distribution system and method utilizes a central pharmacy and database to track all prescriptions for a sensitive drug. Information is kept in the database regarding all physicians allowed to prescribe the sensitive drug, and all patients receiving the drug. Abuses are identified by monitoring data in the database for prescription patterns by physicians and prescriptions obtained by patients. Further verification is made that the physician is eligible to prescribe the drug by consulting a separate database, and optionally whether any actions are taken against the physician. Multiple controls beyond those for normal drugs are imposed on the distribution depending on the sensitivity of the drug.

    摘要翻译: 药物分配系统和方法利用中央药房和数据库跟踪敏感药物的所有处方。 在数据库中保存所有允许开出敏感药物的医生和接受该药物的所有患者的资料。 通过监测数据库中的数据来识别滥用行为,由医生处方方式和患者获得的处方。 进一步验证,医师有资格通过咨询单独的数据库开处方药,以及可选地是否对医生采取任何行动。 根据药物的敏感性,对正常药物的多重控制施加在分布上。

    GAMMA-HYDROXYBUTYRATE COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF DISORDERS
    7.
    发明申请
    GAMMA-HYDROXYBUTYRATE COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF DISORDERS 有权
    甘氨酸 - 羟基丁酸酯组合物及其用于治疗疾病的用途

    公开(公告)号:US20140171505A1

    公开(公告)日:2014-06-19

    申请号:US14045673

    申请日:2013-10-03

    IPC分类号: A61K31/19

    摘要: Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.

    摘要翻译: 本文提供包含γ-羟基丁酸盐(GHB)的混合盐的药物组合物和制剂。 本文还提供制备药物组合物和制剂及其用于治疗睡眠障碍的方法,例如呼吸暂停,睡眠时间紊乱,发作性睡眠,猝倒症,睡眠麻痹,睡眠幻觉,睡眠觉醒,失眠和夜间肌阵挛 。