公开(公告)号：US20250026797A1

公开(公告)日：2025-01-23

申请号：US18903043

申请日：2024-10-01

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Zvi Kelman ,  John P. Marino ,  Svetlana Pavlova Ikonomova

IPC: C07K14/195 ,  C07K1/13 ,  G01N33/58

Abstract: A GID4 N-terminal proline binder includes: a variant of a GID4 protein that includes a mutation, wherein the variant GID4 protein exhibits an increased binding affinity for an N-terminal proline residue as compared to a native GID4 protein.

公开(公告)号：US20240423493A1

公开(公告)日：2024-12-26

申请号：US18705129

申请日：2022-10-28

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Kamran Sayrafian-Pour

IPC: A61B5/05 ,  A61B5/00 ,  A61B5/08

Abstract: A lung fluid monitor monitors a fluid level in a lung and includes: a radiation source disposable on a first body surface and that produces nascent radiation, the nascent radiation: being received by the first body surface, communicated from the first body surface to a lung, attenuated proportionately to an amount of fluid in the lung, and communicated from the lung to a second body surface as attenuated radiation; a radiation detector disposable on the second body surface opposing the first body surface and in electromagnetic communication with the radiation source via the lung and that: receives the attenuated radiation from the lung and produces a detector signal from the attenuated radiation in response to receiving the attenuated radiation.

公开(公告)号：US20240383808A1

公开(公告)日：2024-11-21

申请号：US18669371

申请日：2024-05-20

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Rachel Elizabeth Cook ,  Li-Piin Sung

IPC: C04B20/02 ,  C04B7/02 ,  C04B18/20 ,  C04B28/04

Abstract: The present invention is directed to processes and compositions using post-consumer plastic processed by low temperature milling as a partial cement replacement in a cementitious-based mixture design. The invention discloses ground plastic with a particle size less than or equal to 200 μm as a partial cement replacement at low and high replacement levels for construction applications.

公开(公告)号：US12092652B2

公开(公告)日：2024-09-17

申请号：US17363354

申请日：2021-06-30

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Jason John Gorman ,  Thomas Warren LeBrun ,  David Alexander Long

IPC: G01P15/093

CPC classification number: G01P15/093

Abstract: An optomechanical accelerometer includes: a fiducial mass for a microscale Fabry-Perot optical cavity; a proof mass for the microscale Fabry-Perot optical cavity, such that the proof mass oscillates in a displacement motion toward and away from the fiducial mass in response to acceleration of the optomechanical accelerometer; a basal member; microscale beams that mechanically suspend the proof mass from the basal member; and the microscale Fabry-Perot optical cavity that has a cavity resonance at a cavity resonance wavelength provided by the cavity length, receives excitation radiation at an excitation wavelength that is reflected in the cavity as dynamic cavity light when the excitation wavelength is resonant with the cavity resonance wavelength, and transmits the dynamic cavity light as cavity output light when the dynamic cavity light is produced from the excitation radiation.

公开(公告)号：US20240296368A1

公开(公告)日：2024-09-05

申请号：US18654208

申请日：2024-05-03

Applicant: University of Maryland, College Park ,  Government of the United States of America, as Represented by the Secretary of Commerce

Inventor： Seyed Alireza SEIF TABRIZI ,  Mohammad HAFEZI ,  Yi-Kai LIU

IPC: G06N10/70

CPC classification number: G06N10/70

Abstract: A method for detecting a two-qubit correlated dephasing error includes accessing a signal of a quantum system, where the quantum system includes a plurality of qubits. Every qubit has a nonzero rate of dephasing and some qubits have a nonzero rate of correlated dephasing. The signal further includes information about a matrix that includes diagonal elements and off-diagonal elements. The off-diagonal elements of the matrix are 2s-sparse. The method further includes performing randomized measurements of the off-diagonal elements of the matrix and recovering the matrix based on a direct measurement of the diagonal elements of the matrix.

公开(公告)号：US20240230415A9

公开(公告)日：2024-07-11

申请号：US18121052

申请日：2023-03-14

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Nikolai Nikolaevich Klimov ,  Tobias Kent Herman ,  Zeeshan Ahmed

IPC: G01J5/0821 ,  G01J5/02 ,  G01K15/00

CPC classification number: G01J5/0821 ,  G01J5/0205 ,  G01K15/005

Abstract: A photonic thermometer module assembly includes: a sheath; a sheath bottom plug; a sheath top flange; a top sealing flange; a heat exchanger; a photonic thermometer disposed on the heat exchanger such that the photonic thermometer determines a temperature of the sheath; and an optical fiber array in optical communication with the photonic thermometer and that optically couples the photonic thermometer to an exterior environment of the photonic thermometer module assembly, wherein the photonic thermometer module assembly is compatible with International Temperature Scale of 0 (ITS-90) fixed-point cell infrastructure and conventional drywell and oil-bath calibrations, and the photonic thermometer module assembly provides temperature measurements from −200° C. to +700° C.

公开(公告)号：US20240185109A1

公开(公告)日：2024-06-06

申请号：US18136257

申请日：2023-04-18

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Alexey Vyacheslavovich Gorshkov ,  Jacob Bringewatt ,  Igor Boettcher ,  Pradeep Niroula ,  Przemyslaw Bienias

IPC: G06N10/20

CPC classification number: G06N10/20

Abstract: A process for measuring multiple functions with a quantum sensor network includes: providing a plurality of quantum sensors, each of which is configured for measuring a different analytic function of a set of unknown parameters; preparing the plurality of quantum sensors in a known state; exposing the plurality of quantum sensors to the set of unknown parameters; measuring the plurality of quantum sensors; and calculating the multiple analytic functions of the set of unknown parameters from the measurements of the plurality of quantum sensors

公开(公告)号：US20240133746A1

公开(公告)日：2024-04-25

申请号：US18121052

申请日：2023-03-13

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Nikolai Nikolaevich Klimov ,  Tobias Kent Herman ,  Zeeshan Ahmed

IPC: G01J5/0821 ,  G01J5/02 ,  G01K15/00

CPC classification number: G01J5/0821 ,  G01J5/0205 ,  G01K15/005

Abstract: A photonic thermometer module assembly includes: a sheath; a sheath bottom plug; a sheath top flange; a top sealing flange; a heat exchanger; a photonic thermometer disposed on the heat exchanger such that the photonic thermometer determines a temperature of the sheath; and an optical fiber array in optical communication with the photonic thermometer and that optically couples the photonic thermometer to an exterior environment of the photonic thermometer module assembly, wherein the photonic thermometer module assembly is compatible with International Temperature Scale of 0 (ITS-90) fixed-point cell infrastructure and conventional drywell and oil-bath calibrations, and the photonic thermometer module assembly provides temperature measurements from −200° C. to +700° C.

公开(公告)号：US20240120706A1

公开(公告)日：2024-04-11

申请号：US18483926

申请日：2023-10-10

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Scott Brian Papp ,  Jennifer Anne Black

IPC: H01S5/026 ,  H01S5/11

CPC classification number: H01S5/026 ,  H01S5/11

Abstract: A method of designing a continuous-wave laser source having a target output wavelength and an input laser with a wavelength different from the target output wavelength includes the steps of receiving the target output wavelength, and subordinate properties of the laser source; determining a candidate wavelength of the input laser and materials of the substrate, lower cladding, photonic device layer (PDL), and upper cladding; producing an optimal design of a photonic crystal resonator (PhCR) enabling optical parametric oscillation (OPO); and producing an optimal design of the input and output PhCR waveguide couplers. The OPO is phase-matched.

公开(公告)号：US11905504B2

公开(公告)日：2024-02-20

申请号：US17234298

申请日：2021-04-19

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Mandy Brigitte Esch ,  Longyi Chen

IPC: C12M3/00 ,  C12M1/12 ,  C12M1/00 ,  C12N5/071

CPC classification number: C12M21/08 ,  C12M25/06 ,  C12M29/00 ,  C12N5/0697

Abstract: A body cube for culturing tissue that includes: an organ chip holder; and a body barrier chip and a first body organ chip disposed in the organ chip holder, the first body organ chip including a first cell culture chamber that receives cell culture medium and produces a first tissue in the first cell culture chamber, such that the organ chip holder receives cell culture medium and communicates the cell culture medium to the first cell culture chamber of the first body organ chip in response to rotation of the organ chip holder.