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公开(公告)号:US20230122419A1
公开(公告)日:2023-04-20
申请号:US17794580
申请日:2021-01-19
摘要: A method for detecting nano- and micro-plastics in an aqueous sample suspected of being polluted with nano- or micro-plastics is provided. The method is based on interaction of the nano- and micro-plastics with hyaluronic acid functionalized with a luminescent or fluorescent dye. The luminescent or fluorescent dye is Rhodamine B or the metallorganic complex Ru(bpy)32+.
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公开(公告)号:US20230116307A1
公开(公告)日:2023-04-13
申请号:US17905661
申请日:2021-03-09
IPC分类号: B61L27/04 , B61B5/02 , B61C3/02 , B61C13/00 , B61D15/00 , B61L27/30 , B61L27/70 , B61L25/02 , B61L23/04 , B60L53/30
摘要: A farming system (1) for row crop installations (10) comprises: a first plurality of plants (10A) and a second plurality of fruit or vegetable plants (10B), disposed along a first longitudinal axis (L1) and a second longitudinal axis (L2), respectively, and mutually spaced along a transverse direction (T) to form a first row (F1) and a second row (F2); a supporting structure (11), configured to support the plants and including, for the first row (F1) and the second row (F2), a first plurality of posts (11A) and a second plurality of posts (11B); a first rail (12A), connected to the first plurality of posts (11A); a second rail (12B), connected to the second plurality of posts (11B). The first rail (12A) and the second rail (12B) are oriented longitudinally and spaced transversely from each other to define a track (12). The system comprises a trolley (13), movable along the track (12) and including a movement actuator (131), configured to move the trolley (13) on the track (12).
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公开(公告)号:US20220339610A1
公开(公告)日:2022-10-27
申请号:US17639136
申请日:2020-08-25
摘要: A catalyst having coke wherein the coke, upon analysis by infrared spectroscopy in diffuse reflection, has at least two peaks at a wavelength between 1450 cm−1 and 1700 cm−1.
The aforesaid catalyst having coke can be advantageously used in a process for the production of a diene, preferably a conjugated diene, more preferably 1,3-butadiene, said process having the dehydration of at least one alkenol having a number of carbon atoms greater than or equal to 4.
Preferably, the alkenol having a number of carbon atoms greater than or equal to 4 can be obtained directly from biosynthetic processes, or through catalytic dehydration processes of at least one diol.
When the alkenol is a butenol, the diol is preferably a butanediol, more preferably 1,3-butanediol, even more preferably bio-1,3-butanediol, i.e. 1,3-butanediol deriving from biosynthetic processes.
When the diol is 1,3-butanediol, or bio-1,3-butanediol, the diene obtained with the process is, respectively, 1,3-butadiene, or bio-1,3-butadiene.-
公开(公告)号:US11453634B2
公开(公告)日:2022-09-27
申请号:US16765983
申请日:2018-11-22
发明人: Fabrizio Cavani , Andrea Vassoi
IPC分类号: C07C51/245 , B01J31/28 , C11C3/00 , C07C53/126 , C07C55/18
摘要: A process of preparation of carboxylic acids by oxidative cleavage of compounds having substituted or non-substituted, linear or branched, saturated or unsaturated alkyl chains containing at least one vicinal diol or an epoxide in the presence of an oxidant comprising molecular oxygen and a heterogeneous catalyst comprising a copper oxide.
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公开(公告)号:US20220296710A1
公开(公告)日:2022-09-22
申请号:US17596746
申请日:2020-06-26
发明人: Alberto Danielli , Matteo Calvaresi , Matteo Di Giosia , Andrea Cantelli , Francesco Starinieri , Michela Nigro , Edoardo Sarti
摘要: The present invention relates to a phage or a composition that comprises it, wherein said phage expresses at least one specific recognition element and is furthermore conjugated with at least 300 molecules of a sonosensitiser. The invention further relates to the use of said phage in a sonodynamic therapy.
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公开(公告)号:US10945989B2
公开(公告)日:2021-03-16
申请号:US16131310
申请日:2018-09-14
发明人: Renata Bartesaghi , Fiorenza Stagni
IPC分类号: A61K31/352 , A61P25/00
摘要: The present invention relates to methods of restoring brain development in individuals with Down syndrome with a flavone derivative, 7,8-dihydroxyflavone (7,8-DHF).
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公开(公告)号:US20190300862A1
公开(公告)日:2019-10-03
申请号:US16307708
申请日:2017-06-08
IPC分类号: C12N7/00 , C07K14/005 , A61K35/763
摘要: The present invention is directed to a recombinant herpesvirus which comprises the GCN4 yeast transcription factor or a part thereof fused to or inserted into glycoprotein H and is capable of binding to a target molecule present on a cell for propagation and production of the herpesvirus. The herpesvirus may comprise additional modification in glycoprotein D and/or glycoprotein B for retargeting the herpesvirus to a diseased cell. The present invention is further directed to a nucleic acid and a vector coding for the gH, a polypeptide comprising the gH, and a cell comprising the herpesvirus, nucleic acid, vector or polypeptide. Moreover, the present invention is directed to a cell having accessible on the surface a target molecule for the GCN4 yeast transcription factor or part thereof and to a method for producing the herpesvirus in said cell.
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公开(公告)号:US10421979B2
公开(公告)日:2019-09-24
申请号:US15548731
申请日:2016-02-11
摘要: The present invention relates to the field of disease therapy. More specifically, it relates to a retargeted herpesvirus having a heterologous polypeptide fused to glycoprotein H, wherein the polypeptide targets diseased cells. It also relates to a nucleic acid comprising the genome of the herpesvirus of the invention, a vector comprising this nucleic acid and a cell comprising the nucleic acid or the vector. It further relates to killing cells using the herpesvirus of the invention and to methods for growing it in vitro.
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公开(公告)号:US10323017B2
公开(公告)日:2019-06-18
申请号:US15548512
申请日:2016-02-05
IPC分类号: C07D401/12 , C09D7/40 , C07D213/74 , C07D239/42 , C07D239/48 , C10M133/40 , C09D11/00 , C09K15/30 , C09J11/06 , C08K5/3432 , C08K5/3462 , A61K8/49 , A61Q19/00 , C10M141/06 , C10L1/10 , C10L1/12 , C10L1/232 , C10L10/00 , C09K15/18 , C08K5/34
摘要: A method of preventing or reducing the level of degradation of an organic substrate is described, wherein a composition is formed that includes the organic substrate together with an effective amount of a sacrificial base and a diarylamine antioxidant.
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90.
公开(公告)号:US10197803B2
公开(公告)日:2019-02-05
申请号:US15129750
申请日:2015-03-27
IPC分类号: G02B27/01 , A61B5/00 , G03B21/20 , A61B90/00 , A61B90/50 , G02B27/14 , G06F3/0354 , G06F3/16
摘要: The invention describes augmented reality glasses (1) for medical applications configured to be worn by a user, comprising a frame (15) that supports a glasses lens (2a, 2b), wherein the frame (15) comprises an RGB lighting system comprising RGB-emitting devices (16a, 16b, 16c) configured to emit light beams (B1, B2, B3); first optical systems (17a, 17b, 17c) configured to collimate at least partially said beams (B1, B2, B3) into collimated beams (B1c; B2c; B3c); wherein the frame (15) further comprises a display (3) configured to be illuminated by the RGB lighting system (16) by means of the collimated beams (B1c; B2c; B3c); to receive first images (I) from a first processing unit (10); to emit the first images (I) as second images (IE1) towards the glasses lens (2a, 2b), wherein the lens (2a, 2b) is configured to reflect the second images (IE1) coming from the display (3) as images projected (IP) towards an internal zone (51) of the glasses corresponding to an eye position zone of the user who is wearing the glasses in a configuration for use of the glasses. The invention moreover describes an augmented reality system for medical applications on a user comprising the augmented reality glasses (1) of the invention, biomedical instrumentation (100) configured to detect biomedical and/or therapeutic and/or diagnostic data of a user and to generate first data (D1) representative of operational parameters (OP_S) associated with the user, transmitting means (101) configured to transmit the first data (D1) to the glasses (1); wherein the glasses (1) comprise a first processing unit (10) equipped with a receiving module (102) configured to receive the first data (D1) comprising the operational parameters (OP_S) associated with the user.
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