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公开(公告)号：US10799641B2
公开(公告)日：2020-10-13
申请号：US15533771
申请日：2015-12-08
申请人： Sanofi
IPC分类号： A61M5/315
摘要： A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having an opening, a dose selector operable to set a dose by rotation relative to the housing, a release member controlling movement of a piston in a dispensing direction, and a display comprising a units number wheel and a tens number wheel which are coupled to each other such that a continuous rotation of the units number wheel is translated into an intermittent rotary motion of the tens number wheel. The release member rotates, during dose dispensing, an angle corresponding to the dose set by the dose selector, thereby allowing a piston to move in a dispensing direction.
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公开(公告)号：US10682464B2
公开(公告)日：2020-06-16
申请号：US15517827
申请日：2015-10-06
申请人： Sanofi
发明人： Joseph Butler , Paul Richard Draper
摘要： A drive mechanism of an injection device for setting and dispensing of a dose of a medicament includes a body accommodating a cartridge filled with a medicament, an insert axially displaceable inside the body between a proximal operating position and a distal reset position, a piston rod to operably engage with a piston of the cartridge, a drive sleeve rotationally coupled with the piston rod and is rotationally lockable to the body for setting of a dose and rotationally releasable from the body for dispensing of a dose, respectively. The drive sleeve is axially displaceable relative to the body from a proximal operating position into a distal reset position through an axial connection of the insert and the drive sleeve, where the drive sleeve is rotationally released from the body when in the distal reset position.
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公开(公告)号：US20190381248A1
公开(公告)日：2019-12-19
申请号：US16555772
申请日：2019-08-29
发明人： Frank Erbstein , Paul Richard Draper , Robert Frederick Veasey , David Aubrey Plumptre , Joseph Butler
IPC分类号： A61M5/315
摘要： A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.
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公开(公告)号：US10471218B2
公开(公告)日：2019-11-12
申请号：US15321879
申请日：2015-07-01
申请人： Sanofi
发明人： William Geoffrey Arthur Marsh , Anthony Paul Morris , Joseph Butler , Matthew Meredith Jones , Samuel Keir Steel , Richard James Vincent Avery
摘要： The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), and a piston rod (30) coupled to the housing (10) and to a drive sleeve (40). Rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10). The piston rod (30) is coupled to the housing (10) via a threaded interface (16, 31) with at least two different pitches.
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公开(公告)号：US10441725B2
公开(公告)日：2019-10-15
申请号：US15313905
申请日：2015-05-27
发明人： Matthew Meredith Jones , Samuel Keir Steel , Neal Alexander Blundred , Joseph Butler , Robert Frederick Veasey , David Plumptre
摘要： A dose setting mechanism for a drug delivery device includes a primary drug delivery assembly and a secondary drug delivery assembly. The dose setting mechanism includes a primary dose dial component for setting a dose in the primary drug delivery assembly and a secondary dose dial component for setting a dose in the secondary drug delivery assembly. The primary dose dial component and the secondary dose dial component are configured to rotate during dose setting. A gear mechanism is configured such that in a first phase of the dose setting, rotation of the primary dose dial component is transferred to the secondary dose dial component and such that in a second phase of the dose setting, the secondary dose dial component is decoupled from the primary dose dial component such that rotation of the primary dose dial component is prevented from being transferred to the secondary dose dial component.
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公开(公告)号：US10213560B2
公开(公告)日：2019-02-26
申请号：US14783462
申请日：2014-04-08
申请人： Sanofi
发明人： Joseph Butler , Matthew Jones
摘要： An injection device includes a housing, a dose setting member being operable in a first direction to set a desired dose to be dispensed, and a piston rod being adapted to cooperate with a piston so as to cause a set dose to be injected from a cartridge. Further, a first part and a second part of the injection device are provided, which are adapted to perform a relative rotational movement with respect to each other during dispensing of a dose, and which are adapted to provide a non-visual feedback signal to a user only at the end of dispensing of a set dose. The dose setting member is further operable in a second direction which is opposite to the first direction to cancel a set dose. A third part is movable between a dose setting or cancelling position and a dose dispensing position relative to the first part and/or the second part, which third part contacts the first part and/or the second part in its dose setting or cancelling position or in its dose dispensing position.
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公开(公告)号：US10173005B2
公开(公告)日：2019-01-08
申请号：US14762068
申请日：2014-01-27
发明人： Paul Richard Draper , George Cave , Joseph Butler
摘要： The invention relates to a drug delivery device for administering a drug, comprising: a body adapted to retain a cartridge containing a drug, at least one electrical unit (EU) and a port for electrically contacting the electrical unit (EU), an adapter for attaching an injection needle to the drug delivery device, a safety mechanism (S1 to S6) arranged to prevent access to the port while an injection needle is in fluid communication with the cartridge and arranged to prevent establishing a fluid communication between an injection needle and the cartridge while the port is accessible.
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公开(公告)号：US10064996B2
公开(公告)日：2018-09-04
申请号：US14763863
申请日：2014-01-27
发明人： Paul Richard Draper , George Cave , Joseph Butler , Samuel Steel , David Richard Mercer , Simon Bilton Lewis
摘要： A drug delivery device for administering a drug is presented having a body, at least one electrical unit and a port for electrically contacting the electrical unit, an adapter for attaching an injection needle to the drug delivery device, a safety mechanism arranged to prevent contacting the electrical unit whilst an injection needle is in fluid communication with the drug delivery device and arranged to prevent establishing a fluid communication while the electrical unit is contactable.
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公开(公告)号：US20170304537A1
公开(公告)日：2017-10-26
申请号：US15517827
申请日：2015-10-06
申请人： Sanofi
发明人： Joseph Butler , Paul Richard Draper
摘要： A drive mechanism of an injection device for setting and dispensing of a dose of a medicament includes a body accommodating a cartridge filled with a medicament, an insert axially displaceable inside the body between a proximal operating position and a distal reset position, a piston rod to operably engage with a piston of the cartridge, a drive sleeve rotationally coupled with the piston rod and is rotationally lockable to the body for setting of a dose and rotationally releasable from the body for dispensing of a dose, respectively. The drive sleeve is axially displaceable relative to the body from a proximal operating position into a distal reset position through an axial connection of the insert and the drive sleeve, where the drive sleeve is rotationally released from the body when in the distal reset position.
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公开(公告)号：US20170128674A1
公开(公告)日：2017-05-11
申请号：US15414679
申请日：2017-01-25
发明人： Joseph Butler , David Moore , Paul Richard Draper , Stephen Francis Gilmore , Anthony Paul Morris
CPC分类号： A61M5/31585 , A61M5/31525 , A61M5/31541 , A61M5/31551 , A61M5/31593 , A61M2005/2488 , A61M2005/3125 , A61M2005/3126 , A61M2205/3306 , A61M2205/3375 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/8206 , G01D5/2497 , G01D5/25
摘要： A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with at least first and second tracks together forming an encoder, each track comprising conductive segments and non-conductive segments; and at least first and second groups of contacts configured to engage the first and second tracks respectively at predetermined intervals along the length of the track.
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