公开(公告)号：US08961383B2

公开(公告)日：2015-02-24

申请号：US12595329

申请日：2008-04-09

Applicant: E. Ishmael Parsai ,  John J. Feldmeier

Inventor： E. Ishmael Parsai ,  John J. Feldmeier

IPC: A61M31/00 ,  A61M25/10 ,  A61N5/10 ,  A61M25/00

CPC classification number: A61M25/1002 ,  A61M25/1011 ,  A61M2025/0034 ,  A61M2025/0036 ,  A61M2025/004 ,  A61M2025/1013 ,  A61M2025/1015 ,  A61N5/1016 ,  A61N2005/1018

Abstract: A system is provided for use in brachytherapy where a central tube permits passage of a radioactive source therethrough to deliver a prescribed dosage of radiation. One or more balloons are coaxially positioned around the central tube. At least one balloon includes one or more peripheral tubes extending along at least a portion of the balloon. The peripheral tube is also attached to the high dose rate brachytherapy unit in order to permit passage of a radioactive source therethrough.

Abstract translation: 提供一种用于近距离放射治疗的系统，其中中心管允许放射源通过其中以递送规定剂量的辐射。 一个或多个气囊围绕中心管同轴定位。 至少一个气囊包括沿气囊的至少一部分延伸的一个或多个外围管。 外周管也连接到高剂量率近距离放射治疗单元，以允许放射源通过其中。

公开(公告)号：US08771161B2

公开(公告)日：2014-07-08

申请号：US12642626

申请日：2009-12-18

Applicant: Doug S. Sutton ,  George D. Hermann

Inventor： Doug S. Sutton ,  George D. Hermann

IPC: A61M36/00 ,  A61N5/10

CPC classification number: A61N5/1014 ,  A61N5/1015 ,  A61N2005/1018

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways. The apparatus may include features to prevent overexpansion of the elongate members and/or to facilitate rapid collapse of the elongate members.

Abstract translation: 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。 该装置可以包括防止细长构件的过度膨胀和/或促进细长构件的快速塌缩的特征。

公开(公告)号：US20130225902A1

公开(公告)日：2013-08-29

申请号：US13861195

申请日：2013-04-11

Applicant: JACK C. WHITE ,  DAVID WESLEY STEPHENS ,  AMIT PRAKASH GOVIL ,  JOSHUA J. BERGMAN ,  NATHAN CHRISTOPHER GRIFFITH ,  KYLE KEVIN MILLAGE

Inventor： JACK C. WHITE ,  DAVID WESLEY STEPHENS ,  AMIT PRAKASH GOVIL ,  JOSHUA J. BERGMAN ,  NATHAN CHRISTOPHER GRIFFITH ,  KYLE KEVIN MILLAGE

IPC: A61N5/10

CPC classification number: A61N5/1015 ,  A61M29/02 ,  A61N5/1007 ,  A61N2005/1008 ,  A61N2005/1018 ,  A61N2005/1024

Abstract: A method for brachytherapy in a lumpectomy cavity of a breast including, positioning a distal end of a brachytherapy device within the cavity, expanding an expandable surface portion located between proximal and distal ends of the device within the cavity, the source lumen tubes defining a curved configuration within the cavity; and positioning a source of radiation sequentially within one or more source lumens of the source lumen tubes according to a brachytherapy treatment plan. The device includes an inner tube, and a plurality of source lumen tubes located around the inner tube and including distal ends secured together with the inner tube at the distal end disposed within the body cavity, the source lumen tubes comprising proximal portions sufficiently long to extend outside the breast.

公开(公告)号：US08517907B2

公开(公告)日：2013-08-27

申请号：US12277286

申请日：2008-11-24

Applicant: Eduardo Chi Sing ,  Tommy G. Nguyen ,  George D. Hermann ,  Than Nguyen ,  Doug S. Sutton

Inventor： Eduardo Chi Sing ,  Tommy G. Nguyen ,  George D. Hermann ,  Than Nguyen ,  Doug S. Sutton

IPC: A61M36/12

CPC classification number: A61N5/1015 ,  A61N2005/1018

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

公开(公告)号：US08328711B2

公开(公告)日：2012-12-11

申请号：US11959227

申请日：2007-12-18

Applicant: Donna Allan ,  Greg Amante

Inventor： Donna Allan ,  Greg Amante

IPC: A61N5/00

CPC classification number: A61N5/1015 ,  A61N2005/1005 ,  A61N2005/1018

Abstract: A brachytherapy treatment device includes at least one tubular insertion member and an expandable member. The tubular insertion member has proximal and distal ends and at least one radiation source lumen disposed along its length and branching at the distal end to provide a plurality of selectable radiation source lumens each configured to receive a radiation source. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. In another embodiment, a brachytherapy treatment device may also include a plurality of selectable radiation source lumens forming an arcuate shape with respect to the longitudinal axis. Additional brachytherapy treatment devices and methods for performing brachytherapy and for forming an asymmetric radiation dosing profile are also disclosed.

Abstract translation: 近程放射治疗装置包括至少一个管状插入构件和可扩张构件。 管状插入构件具有近端和远端以及至少一个辐射源腔，沿着其长度设置并在远端分支，以提供多个可选择的辐射源腔，每个被配置为接收辐射源。 可扩张构件设置在管状插入构件的远端上且围绕管状插入构件的远端。 在另一个实施例中，近距离放射疗法治疗装置还可以包括相对于纵向轴线形成弓形形状的多个可选择的辐射源腔。 还公开了用于进行近距离放射治疗和形成不对称辐射剂量分布的附加近距离放射线治疗装置和方法。

公开(公告)号：US08079946B2

公开(公告)日：2011-12-20

申请号：US11593784

申请日：2006-11-06

Applicant: Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

Inventor： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC: A61N5/00

CPC classification number: A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

Abstract: The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

Abstract translation: 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US07862498B2

公开(公告)日：2011-01-04

申请号：US11868483

申请日：2007-10-06

Applicant: Tommy G. Nguyen ,  Than Nguyen ,  Doug S. Sutton

Inventor： Tommy G. Nguyen ,  Than Nguyen ,  Doug S. Sutton

IPC: A61M36/00

CPC classification number: A61N5/1014 ,  A61N5/1015 ,  A61N2005/1018

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways. The apparatus may include features to prevent overexpansion of the elongate members and/or to facilitate rapid collapse of the elongate members.

Abstract translation: 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。 该装置可以包括防止细长构件的过度膨胀和/或促进细长构件的快速塌缩的特征。

公开(公告)号：US07862497B2

公开(公告)日：2011-01-04

申请号：US11935348

申请日：2007-11-05

Applicant: L. Michael Cutrer ,  Fredrick Wintch ,  Richard A. Terwilliger ,  John Zhang ,  David Bossi

Inventor： L. Michael Cutrer ,  Fredrick Wintch ,  Richard A. Terwilliger ,  John Zhang ,  David Bossi

IPC: A61N5/00

CPC classification number: A61N5/1015 ,  A61N2005/1018

Abstract: A brachytherapy device may include a plurality of rods, each configured to move between a straightened position and a bowed position, the plurality of rods configured to collectively form a shaft while each rod is in the straightened position and to collectively form at least one cage while at least some of the rods are in the bowed position, at least some of the rods having lumens that are configured to receive and hold radioactive material. A brachytherapy device may further include a rotatable mechanism configured to cause at least some of the plurality of rods to move between the straightened position and the bowed position upon rotation of the rotatable mechanism.

Abstract translation: 近程放射治疗装置可以包括多个杆，每个杆被构造成在矫直位置和弯曲位置之间移动，多个杆构造成在每个杆处于矫直位置时共同形成轴，并且共同形成至少一个笼，而 杆中的至少一些处于弯曲位置，至少一些杆具有被配置为容纳和保持放射性材料的腔。 近程放射治疗装置还可以包括可旋转机构，其被配置为当可旋转机构旋转时使多个杆中的至少一些杆在矫正位置和弯曲位置之间移动。

公开(公告)号：US20100204537A1

公开(公告)日：2010-08-12

申请号：US12764892

申请日：2010-04-21

Applicant: George D. Hermann ,  Eduardo Chi Sing ,  Gail S. Lebovic ,  Mark A. Cole ,  Mark A. Ritchart ,  Than Nguyen

Inventor： George D. Hermann ,  Eduardo Chi Sing ,  Gail S. Lebovic ,  Mark A. Cole ,  Mark A. Ritchart ,  Than Nguyen

IPC: A61M36/12

CPC classification number: A61N5/1015 ,  A61N2005/1018

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract translation: 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。

公开(公告)号：US20100204536A1

公开(公告)日：2010-08-12

申请号：US12557040

申请日：2009-09-10

Applicant: L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

Inventor： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

IPC: A61M36/12

CPC classification number: A61N5/1015 ,  A61N2005/1018

Abstract: A brachytherapy device for treating tissue within a cavity of a body. The device may include a first set of tubes configured to be inserted into the cavity through an opening at the surface of the body. Each of the tubes may have an external end and an interior channel beginning at the external end that is configured to receive radioactive material. The external ends of the tubes may be bundled together. The tubes may be of a length that causes the external ends to be near the opening in the surface of the body while the tubes are in the cavity. A seal may be configured to prevent fluid that originates from the cavity from entering into the external ends of the tubes while they are near the opening in the surface of the body. The seal may include a gasket that is pressed against the external ends of the tubes. The gasket may have openings that align with channels within the external ends of the tubes.

Abstract translation: 一种用于治疗身体空腔内的组织的近距离放射治疗装置。 该装置可以包括构造成通过身体表面处的开口插入空腔中的第一组管。 每个管可以具有外部端和从外部端开始的内部通道，其构造成接收放射性材料。 管的外端可以捆扎在一起。 管可以具有这样的长度，即当管在空腔中时，外端在壳体表面的开口附近。 密封件可以构造成防止来自腔的流体在它们靠近体表面的开口处时进入管的外端。 密封件可以包括被压靠在管的外端的垫圈。 垫圈可以具有与管的外端内的通道对准的开口。