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公开(公告)号：US11883098B2
公开(公告)日：2024-01-30
申请号：US18068566
申请日：2022-12-20
发明人： Nikolai Suchkov , Siegfried Wahl
CPC分类号： A61B3/1015 , A61B3/0091 , A61B3/12 , A61B3/14 , G02C7/027
摘要： A device and a method for determining an ocular aberration of at least one eye of a user are disclosed. The device contains a wavefront sensing unit for measuring at least one optical wavefront with at least one light beam, from which an ocular aberration of the at least one eye of the user is determined. The device further contains at least one diffractive element for generating multiple diffraction orders in the light beam in two meridians in a manner that the multiple diffraction orders are spatially separated on the wavefront sensing unit and in the eye of the user. The device and the method allow generating an ocular defocus map in a one-shot assessment in real-time, especially by employing an automated measurement of the ocular aberrations with regard to different eccentricities of the eye of the user in two meridians.
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公开(公告)号：US11877799B2
公开(公告)日：2024-01-23
申请号：US17258904
申请日：2019-07-30
CPC分类号： A61B3/102 , A61B5/7207 , G01B9/02044 , G01B9/02091 , G06T7/269 , G06T11/005 , G06T11/008 , G06T2207/10101 , G06T2207/20021 , G06T2210/41
摘要： The present invention relates to the field of instruments for visualizing the inner structures of the human body, and in particular of the eye. More specifically, its object is an optical coherence tomography system and method of the “Fourier-domain” type with the removal of unwanted artifacts through digital image processing.
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公开(公告)号：US11877798B2
公开(公告)日：2024-01-23
申请号：US17035910
申请日：2020-09-29
申请人： NIDEK CO., LTD.
发明人： Koichi Ito
CPC分类号： A61B3/102 , A61B3/0008 , A61B3/0025 , A61B3/0058
摘要： An ophthalmologic imaging apparatus having an OCT optical system for acquiring OCT data of a tissue of a subject eye based on a spectral interference signal of measurement light emitted to the tissue and reference light. The apparatus further has a second optical system for acquiring a front image of the tissue; an optical element having asymmetry and arranged on a common optical path of the OCT optical system and the second optical system; and an arithmetic controller that associates an OCT data acquisition position with coordinates of the front image while taking at least a difference in distortion caused by the optical element between the OCT optical system and the second optical system into consideration.
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公开(公告)号：US20240016380A1
公开(公告)日：2024-01-18
申请号：US18256758
申请日：2021-12-10
申请人： EYE CO PTY LTD
CPC分类号： A61B3/1241 , A61B5/004 , A61B5/4082 , A61B5/7275 , A61B5/7282 , G06T7/0016 , A61B3/0025 , A61B3/102 , G06T2207/10101 , G06T2207/20032 , G06T2207/20076 , G06T2207/20084 , G06T2207/30041
摘要： A method of detecting one or more change in an eye and a method diagnosing or providing an indication of an eye disease or eye condition or a neurodegenerative disease or condition, or a predisposition thereto are disclosed. The method of detection comprises comparing an image of the eye with at least one asynchronous image of the eye to thereby detect the one or more change in the eye wherein the change comprises a darkening or lightening in pigment of the Retinal Pigmented Epithelium (RPE) in the macula. The method of diagnosing or providing an indication of an eye disease or eye condition or a neurodegenerative disease or condition or a predisposition thereto comprises the same comparison and when the change is detected, providing a diagnosis of, indication of or to an eye disease or eye condition or a neurodegenerative disease or condition or a predisposition thereto.
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公开(公告)号：US20240016378A1
公开(公告)日：2024-01-18
申请号：US18351389
申请日：2023-07-12
申请人： Alcon Inc.
发明人： Zsolt Bor , Alireza Malek Tabrizi
CPC分类号： A61B3/102 , A61B3/0025
摘要： Particular embodiments disclosed herein provide a method for training a machine learning model to estimate the clinical significance of floaters in a patient's eye. One or more images, such as SLO images or en face retinal OCT images, are evaluated to identify shaded regions corresponding to floaters. The shaded regions are measured and the measurements processed using a machine learning model to obtain an estimated significance. The machine learning model is then updated according to a comparison of the estimated significance to a human-assigned clinical significance. The machine learning model may additionally or alternatively be updated by evaluating the estimated category with respect to visibility threshold data, such as one or more visibility threshold surfaces defined with respect to two or more variables.
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公开(公告)号：US11871994B2
公开(公告)日：2024-01-16
申请号：US17494273
申请日：2021-10-05
申请人： Topcon Corporation
发明人： Yasufumi Fukuma , Kazuhiro Oomori
摘要： The object of the present invention is to develop an ophthalmologic microscope of a new method that increases the degree of freedom in the optical design in the Galilean ophthalmologic microscope provided with an OCT optical system. The present invention provides an ophthalmologic microscope, wherein an observation optical system, an objective lens, and an OCT optical system are placed in such a way that the optical axis of the OCT optical system does not penetrate through objective lens, and the optical axis of the observation optical system and the optical axis of the OCT optical system are non-coaxial, and wherein the ophthalmologic microscope further comprises a SLO optical system that scans a light ray which is a visible ray, a near infrared ray, or an infrared ray and guides the light to the subject's eye so as to become substantially coaxial with the optical axis of the OCT optical system.
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公开(公告)号：US11864833B2
公开(公告)日：2024-01-09
申请号：US16948992
申请日：2020-10-08
发明人： Yan Zhou , Willem Crone , John Allison
CPC分类号： A61B3/14 , A61B3/0008 , A61B3/125 , A61B3/1208 , A61B3/1241 , G02B6/0008
摘要： An eye-imaging apparatus and system is described including circular fiber array ends arranged at skewed angles relative to the optical axis of the imaging path, a light intensity distribution converter along the illumination path to convert a bell-shaped distribution into a top-hat distribution, an image sensor, and high frequency response light source(s) operating in flash illumination mode in synchronization with the image sensor. As a result, unnecessary exposure of illumination light to a patient eye is minimized while the illumination light can span a wide enough coverage range with desired intensity and spectral distribution to cover the desired angular field of view and spectral range on a retina.
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68.发明公开公开(公告)号：US20240000311A1
公开(公告)日：2024-01-04
申请号：US18251065
申请日：2021-10-25
发明人： Christian Münster , Gregor Stobrawa
IPC分类号： A61B3/107 , A61B3/10 , A61B3/00 , H04N23/957 , H04N23/56
CPC分类号： A61B3/107 , A61B3/1015 , A61B3/0008 , H04N23/957 , H04N23/56
摘要： Using the present solution, it is possible both to determine optical aberrations and/or the topography and to simultaneously or immediately successively record reference images of an eye. Within the scope of the method, the eye is illuminated with different illumination patterns by means of an illumination unit, and the light reflected by the eye is recorded by a plenoptic camera sensor and evaluated by a control and evaluation unit. According to the invention, the eye is illuminated with different illumination patterns which differ in respect of their intensity distribution and illumination direction, the light reflected by the eye is imaged onto the plenoptic camera sensor and the topography and/or optical aberrations and/or reference images of the illuminated eye are determined from the image data of the plenoptic camera sensor on the basis of the utilized illumination pattern. Even though the solution is especially provided for applications in ophthalmology, it can also be applied in other specialist fields and in industry.
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公开(公告)号：US11857260B2
公开(公告)日：2024-01-02
申请号：US16649437
申请日：2018-09-19
发明人： Eliezer Glik , Sam Kavusi , Ryan Kramer , Todd Whitehurst
CPC分类号： A61B3/14 , A61B3/113 , A61B3/12 , G02F1/1334
摘要： Introduced here are retinal cameras having optical stops whose size and/or position can be modified to increase the size of the space in which an eye can move while being imaged. In some embodiments, an optical stop is mechanically moved to recover retinal image quality as the subject shifts their eye. In some embodiments, an optical stop is digitally created using a pixelated liquid crystal display (LCD) layer having multiple pixels that are individually controllably. In some embodiments, multiple non-pixelated LCD layers are connected to one another to form a variable transmission stack, and each LCD layer within the variable transmission stack may be offset from the other LCD layers. In such embodiments, the optical stop can be moved by changing which LCD layer is active at a given point in time.
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公开(公告)号：US20230414095A1
公开(公告)日：2023-12-28
申请号：US18253603
申请日：2021-11-18
发明人： Hansford HENDARGO , Eric LYNCH
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B2505/05 , A61B2576/02
摘要： The invention relates to a processing system for use with optical coherence tomography imaging means for imaging a subject, the processing system being configured to repeatedly perform an image processing process (300), comprising the following steps: receiving (312) a scan data set from the subject (190) being acquired by means of optical coherence tomography, performing (314) data processing on the scan data set, including applying (316) dispersion correction based on a current set (370) of dispersion coefficients, and providing (318) a dispersion corrected image data set of the subject for an image of the subject to be displayed; and the processing system further being configured to repeatedly perform a dispersion coefficient adapting process (340), at least in part, in parallel to the image processing process (300), comprising the following steps: receiving (342) a scan data set from the subject being acquired by means of optical coherence tomography, adapting (344) dispersion coefficients by means of an optimization process (346) performed on the scan data set, and providing (348) a set (372) of adapted dispersion coefficients to be used to update the current set (370) of dispersion coefficients; and the processing system further being configured to update (350) the current set (370) of dispersion coefficients based on the set (372) of adapted dispersion coefficients, to an optical coherence tomography imaging system and a corresponding method.
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