公开(公告)号：US08883645B2

公开(公告)日：2014-11-11

申请号：US13941240

申请日：2013-07-12

Applicant: California Institute of Technology

Inventor： Chieh-Feng Chang ,  Aditya Rajagopal ,  Axel Scherer

IPC: H01L21/311 ,  H01L29/66 ,  H01L29/423 ,  H01L29/06

CPC classification number: H01L29/66477 ,  H01L29/0673 ,  H01L29/4232

Abstract: Methods for fabrication of nanopillar field effect transistors are described. These transistors can have high height-to-width aspect ratios and be CMOS compatible. Silicon nitride may be used as a masking material. These transistors have a variety of applications, for example they can be used for molecular sensing if the nanopillar has a functionalized layer contacted to the gate electrode. The functional layer can bind molecules, causing an electrical signal in the transistor.

Abstract translation: 描述了纳米柱场效应晶体管的制造方法。 这些晶体管可以具有高的高宽比和CMOS兼容性。 氮化硅可以用作掩模材料。 这些晶体管具有各种应用，例如，如果纳米柱具有与栅电极接触的功能化层，则它们可用于分子感测。 功能层可以结合分子，在晶体管中引起电信号。

公开(公告)号：US20130327645A1

公开(公告)日：2013-12-12

申请号：US13967108

申请日：2013-08-14

Applicant: California Institute of Technology

Inventor： Sameer Walavalkar ,  Axel Scherer ,  Thomas A. Tombrello ,  Aditya Rajagopal ,  Andrew P. Homyk ,  Erika Garcia

IPC: G01N27/447

CPC classification number: G01N27/447 ,  B82Y30/00 ,  C12Q1/6869 ,  G01N33/48721 ,  C12Q2563/116 ,  C12Q2565/631

Abstract: Methods and devices for sequencing nucleic acids are disclosed herein. Devices are also provided herein for measuring DNA with nano-pores sized to allow DNA to pass through the nano-pore. The capacitance can be measured for the DNA molecule passing through the nano-pore. The capacitance measurements can be correlated to determine the sequence of base pairs passing through the nano-pore to sequence the DNA.

Abstract translation: 本文公开了用于测序核酸的方法和装置。 本文还提供了用于测量具有大小允许DNA穿过纳米孔的纳米孔的DNA的装置。 可以测量通过纳米孔的DNA分子的电容。 电容测量可以相关，以确定通过纳米孔的碱基对序列来对DNA进行排序。