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公开(公告)号：US20190280858A1
公开(公告)日：2019-09-12
申请号：US16297438
申请日：2019-03-08
Applicant: Arizona Board of Regents on Behalf of Northern Arizona University , Government of the United States of America, as represented by the Secretary of the Air Force
Abstract: A computing device includes an array of addressable elements. Each addressable element is a hardware element that generates a substantially consistent response when interrogated. The device includes a processor coupled to the array of addressable elements and configured to communicate using a communication network. The processor receives a public key, and processes the public key to produce at least a set of addresses. Each address in the set of addresses identifies one or more hardware elements in the array of addressable elements. The processor generates a set of responses by interrogating the one or more hardware elements in the array of addressable elements identified by the set of addresses according to a set of reading instructions, appends the responses in the set of responses to generate a private key, receives an encrypted message and decrypts the encrypted message using the private key to generate an unencrypted message.
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公开(公告)号：US20190238348A1
公开(公告)日：2019-08-01
申请号：US16375771
申请日：2019-04-04
Inventor： Bertrand Francis Cambou
CPC classification number: H04L9/3278 , G06F21/44 , G06F2221/2103 , H04L9/0643 , H04L9/0866 , H04L9/0869 , H04L9/3226
Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys, and thereby is immune to traditional database hacking attacks.
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公开(公告)号：US20190095610A1
公开(公告)日：2019-03-28
申请号：US16201827
申请日：2018-11-27
Inventor： Bertrand Francis Cambou
Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys. and thereby is immune to traditional database hacking attacks.
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公开(公告)号：US10213478B2
公开(公告)日：2019-02-26
申请号：US14949965
申请日：2015-11-24
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： David Engelthaler , Elizabeth Driebe , Hongwei “Holly” Yin , Michael Valentine , Donald Chow , Jolene Bowers , Paul Keim
IPC: A61K31/135 , A61K31/497 , A61K31/195 , A61K38/13 , A61K31/7135 , A61K31/58 , A61K31/5377 , A61K31/5415 , A61K31/4196 , A61K31/496 , A61K31/495 , A61K45/06 , A61K31/138 , A61K31/277 , A61K31/353 , A61K31/404 , A61K31/4174 , A61K31/428 , A61K31/4741 , A61K31/609
Abstract: The present invention comprises methods of treating an infection using a pharmaceutical composition comprising an active ingredient selected from Table 1. In some aspects, the infection can be caused by one or more pathogens, including fungal pathogens. For example, the infection may be Valley Fever.
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公开(公告)号：US20190040455A1
公开(公告)日：2019-02-07
申请号：US16076608
申请日：2017-02-11
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： Elizabeth Driebe , Paul Keim , David Engelthaler , Jolene Bowers , Nate Nieto
IPC: C12Q1/689
Abstract: The present invention relates to method of detecting and characterizing one or more Borrelia species causing Lyme Disease or tick-borne relapsing fever within a sample from a subject, the method comprising: a) subjecting DNA and/or RNA from the sample to a PCR amplification reaction using primer pairs targeting at least one region of Borrelia 16S rRNA and at least one region of flaB, ospA, ospB, ospC, glpQ, 16S-23S intergenic spacer (IGS1), 5S-23S intergenic spacer (IGS2), bbk32, dbpA, dbpB, and/or p66; and b) analyzing amplification products resulting from the PCR amplification reaction to detect the one or more Borrelia species.
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Patent Agency Ranking
公开(公告)号：US20190024139A1
公开(公告)日：2019-01-24
申请号：US15773270
申请日：2016-11-03
Applicant: The Translational Genomics Research Institute , Arizona Board of Regents on Behalf of Northern Arizona University
Inventor： Elizabeth Driebe , Jolene Bowers , David Engelthaler , Paul Keim
Abstract: Embodiments of the invention include methods of identifying microorganisms and/or diagnosing infections in subjects cause by microorganisms. Embodiments of the invention may also include further characterizing (e.g., determining the presence of one or more antibiotic resistance markers) the microorganisms and determining a strain identity of the microorganisms.
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公开(公告)号：US20180343129A1
公开(公告)日：2018-11-29
申请号：US16036477
申请日：2018-07-16
Inventor： Bertrand Cambou
CPC classification number: H04L9/3278 , H04L9/006 , H04L9/0643 , H04L9/0662 , H04L9/3226 , H04L63/083
Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys, and thereby is immune to traditional database hacking attacks.
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公开(公告)号：US20180274011A1
公开(公告)日：2018-09-27
申请号：US16005012
申请日：2018-06-11
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： David Engelthaler , Elizabeth Driebe , Erin Kelley , Paul Keim
IPC: C12Q1/689
Abstract: Embodiments of the invention provide a method of genotyping a C. gattii sample, which can include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the C. gattii genome that can provide definitive genotype information to distinguish between one or more types or subtypes of C. gattii.
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公开(公告)号：US10050796B2
公开(公告)日：2018-08-14
申请号：US15347721
申请日：2016-11-09
Inventor： Bertrand Francis Cambou
Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys, and thereby is immune to traditional database hacking attacks.
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公开(公告)号：US20180185420A1
公开(公告)日：2018-07-05
申请号：US15568793
申请日：2016-04-25
Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventor： Cindy Liu , Lance B. Price
IPC: A61K35/741 , A61K31/351 , A61K9/00
CPC classification number: A61K35/741 , A61K9/0043 , A61K31/351
Abstract: Embodiments of the invention provide a method of reducing colonization of a subject's anterior nares and/or nasal cavity by a microorganism (e.g., Staphylococcus aureus). In some aspects, the method may include administering a pharmaceutical composition to the subject, wherein the pharmaceutical composition comprises a therapeutically effective amount of at least one probiotic.
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