公开(公告)号：US20120225117A1

公开(公告)日：2012-09-06

申请号：US13510845

申请日：2010-11-15

Applicant: Takeshi Isoda ,  Yasuyuki Motokui ,  Takeshi Wada

Inventor： Takeshi Isoda ,  Yasuyuki Motokui ,  Takeshi Wada

IPC: A61K9/133 ,  A61K31/7068 ,  A61P35/00 ,  A61P31/04 ,  A61P29/00 ,  A61P3/02 ,  A61P39/06 ,  A61K31/365 ,  A61P31/10 ,  B82Y40/00 ,  B82Y5/00

CPC classification number: B01J13/04 ,  A61K9/113 ,  A61K9/127 ,  B01J13/12

Abstract: The present invention provides a liposome production process which enables production of a liposome that has a nano-size particle diameter and a high water-soluble drug encapsulation rate. The process for producing a W1/O/W2 emulsion of the present invention includes the steps of (1) emulsifying an organic solvent (O) that is a volatile organic solvent, an aqueous solvent (W1) and a mixed lipid component (F1) to give a W1/O emulsion; and (2) dispersing the W1/O emulsion produced in step (1) in an aqueous solvent (W2) by use of a porous membrane, to give a W1/O/W2 emulsion, wherein the porous membrane has been surface-treated with a hydrophilic drug so as to allow its surface to have a water contact angle of 0 to 42° in the air.

Abstract translation: 本发明提供了能够生产具有纳米尺寸粒径和高水溶性药物包封率的脂质体的脂质体制造方法。 制备本发明的W1 / O / W2乳液的方法包括以下步骤：（1）乳化作为挥发性有机溶剂的有机溶剂（O），水性溶剂（W1）和混合脂质成分（F1） 得到W1 / O乳液; 和（2）通过使用多孔膜将步骤（1）中制备的W1 / O乳液分散在水性溶剂（W2）中，得到W1 / O / W2乳液，其中多孔膜已经用 一种亲水药物，以使其表面在空气中具有0至42°的水接触角。

公开(公告)号：US07933477B2

公开(公告)日：2011-04-26

申请号：US12400179

申请日：2009-03-09

Applicant: Yasuhiro Shigeno ,  Hiroshi Nakagawa ,  Takeshi Isoda ,  Kosuke Sasada

Inventor： Yasuhiro Shigeno ,  Hiroshi Nakagawa ,  Takeshi Isoda ,  Kosuke Sasada

IPC: G05B6/26 ,  G05B6/42 ,  H04M1/00

CPC classification number: G02B6/3604 ,  G02B6/42

Abstract: An optical transmission hinge apparatus includes a first hinge portion for pivotally interconnecting a first casing and a second casing about a first axis, a first optical device provided in the first casing, a second optical device provided in the second casing and an optical guide path member for interconnecting the first optical device and the second optical device to enable optical transmission therebetween. The optical guide path member includes a bent portion, a first portion formed on one side of the bent portion and a second portion formed on the other side of the bent portion. The first portion is provided in the first casing to be coaxial with the first hinge portion, with a terminal end of the first portion being in opposition to the first optical device. The second portion is provided in the second casing, with a terminal end of the second portion being in opposition to the second optical device.

Abstract translation: 光传输铰链装置包括第一铰链部分，用于将第一壳体和第二壳体围绕第一轴线枢转地互连，设置在第一壳体中的第一光学装置，设置在第二壳体中的第二光学装置和光导路径部件 用于互连第一光学装置和第二光学装置以使它们之间能够进行光传输。 光导路构件包括弯曲部分，形成在弯曲部分一侧的第一部分和形成在弯曲部分另一侧上的第二部分。 第一部分设置在第一壳体中以与第一铰链部分同轴，第一部分的终端与第一光学装置相对。 第二部分设置在第二壳体中，第二部分的末端与第二光学装置相对。

公开(公告)号：US07686522B2

公开(公告)日：2010-03-30

申请号：US11978812

申请日：2007-10-29

Applicant: Keiji Mine ,  Hiroshi Nakagawa ,  Takeshi Isoda

Inventor： Keiji Mine ,  Hiroshi Nakagawa ,  Takeshi Isoda

IPC: G02B6/36

CPC classification number: G02B6/4204 ,  G02B6/32 ,  G02B6/4246

Abstract: An optical coupling component for use in an optical communication connector is provided which comprises a pair of columnar sending side and receiving side optical functional sections and a joint section integrally molded with the optical functional sections and made from the same material as the material of the optically functional sections and having joint regions adjoining the side walls of the optical functional sections, the joint regions of the joint section having a circumferential length along the side walls of the optically functional sections which is equal to or less than a half circumference of the optically functional sections.

Abstract translation: 提供了一种用于光通信连接器的光耦合部件，其包括一对柱状发送侧和接收侧光学功能部分以及与光学功能部分一体模制的接合部分，并且由与光学材料材料相同的材料制成 功能部分，并且具有与光学功能部分的侧壁相邻的接合区域，接合部分的接合区域沿着光学功能部分的侧壁具有等于或小于光学功能部分的半圆周的周长 部分。

公开(公告)号：US07628546B2

公开(公告)日：2009-12-08

申请号：US11442370

申请日：2006-05-25

Applicant: Keiji Mine ,  Hiroshi Nakagawa ,  Takeshi Isoda

Inventor： Keiji Mine ,  Hiroshi Nakagawa ,  Takeshi Isoda

IPC: G02B6/36

CPC classification number: G02B6/4246 ,  G02B6/3881 ,  G02B6/4204 ,  G02B6/4292

Abstract: The object of the present invention is to suppress a decrease in the optical function of a sleeve by ensuring that a liquid chemical substance is not apt to remain on a peripheral surface of the sleeve even when the liquid chemical substance enters a connector. The present invention relates to an optical connector which is connected to an optical plug holding an optical fiber to a terminal end of which a ferrule is attached. The optical connector of the present invention has a guide pipe into which a ferrule is inserted and on an inner circumferential surface of which a supporting portion (a convexity) is formed, a light-emitting device, a light-receiving device, and a sleeve which is positioned by the supporting portion and optically connects the light-emitting device, the light-receiving device and the optical fiber. According to the present invention, there is a space between the guide pipe and the sleeve and, therefore, the phenomenon that a chemical substance adheres to a wide area and remains does not occur.

Abstract translation: 本发明的目的是通过确保液体化学物质即使当液体化学物质进入连接器时也不容易残留在套筒的周面上，从而抑制套筒的光学功能的降低。 光连接器技术领域本发明涉及一种光连接器，该光连接器连接到一个光纤插头，该光插头将一光纤固定在一个端子上，该终端安装一个插芯。 本发明的光连接器具有插入套圈的导管，在其内周面上形成有支撑部（凸部）的导光管，发光元件，受光元件以及套筒 其由支撑部分定位并且光学连接发光装置，光接收装置和光纤。 根据本发明，在导管和套管之间存在空间，因此，不会发生化学物质粘附到广泛区域并保留的现象。

公开(公告)号：US07371015B2

公开(公告)日：2008-05-13

申请号：US11639779

申请日：2006-12-15

Applicant: Naoya Takehara ,  Hiroshi Nakagawa ,  Takeshi Isoda

Inventor： Naoya Takehara ,  Hiroshi Nakagawa ,  Takeshi Isoda

IPC: G02B6/36

CPC classification number: G02B6/421 ,  G02B6/4246 ,  G02B6/4292

Abstract: Attachments are respectively attached to one ends of a pair of light guides, which are integrally formed via a connecting portion, such that the attachments surround the one ends of the light guides. The one ends protrude from a rear face of a receptacle body and are opposed to a light-emitting device and a light-receiving device, respectively. The attachments are inserted and positioned in guide holes formed respectively on the light-emitting device and the light-receiving device, and the optical axes of the pair of light guides and the optical axes of the light-emitting device and the light-receiving device are aligned with each other.

Abstract translation: 附件分别安装在一对导光体的一端，它们通过连接部分整体形成，使得附件围绕光导的一端。 一端从插座主体的后表面突出并分别与发光装置和光接收装置相对。 将附件插入并定位在分别形成在发光装置和光接收装置上的引导孔中，并且一对光导的光轴和发光装置的光轴和光接收装置 彼此对齐。

公开(公告)号：US06910810B2

公开(公告)日：2005-06-28

申请号：US10411778

申请日：2003-04-11

Applicant: Keiji Mine ,  Hiroshi Nakagawa ,  Takeshi Isoda

Inventor： Keiji Mine ,  Hiroshi Nakagawa ,  Takeshi Isoda

IPC: G02B5/04 ,  G02B6/28 ,  G02B6/42 ,  G02B6/36

CPC classification number: G02B6/4246 ,  G02B6/4214

Abstract: An optical guide 43 is partly buried in a lens 43 on the diameter of its aperture, the lens 43 converging received light incident from the end face of an optical fiber onto a light receiving element 15 and the optical conductor 33 having a refractive index larger than that of the lens 43. The optical guide 33 is composed of a buried portion 33-1 and an extending portion 33-2, and transmitting light 22 incident on the optical guide 33 from the end face 33c of the extending portion 33-2 is reflected by a reflecting surface 33a and launched into the optical fiber. The transmitting light 22 is guided by the optical guide 33 to the end face of the optical fiber without leakage to the receiving-side portion.

Abstract translation: 光导43部分地埋在透镜43的孔径的直径上，透镜43将从光纤端面入射的接收光会聚在光接收元件15上，而光导体33的折射率大于 透镜43的。 光导33由埋入部33-1和延伸部33-2构成，从延伸部33-2的端面33c入射到导光体33的透光22被反射面 33 a发射入光纤。 透光22由光导33引导到光纤的端面，而不泄漏到接收侧部分。

公开(公告)号：US06436870B1

公开(公告)日：2002-08-20

申请号：US09652954

申请日：2000-08-31

Applicant: Masahiko Iijima ,  Takao Hashimoto ,  Yoshinobu Okayasu ,  Takeshi Isoda

Inventor： Masahiko Iijima ,  Takao Hashimoto ,  Yoshinobu Okayasu ,  Takeshi Isoda

IPC: B01J2300

CPC classification number: B01J23/8898 ,  B01J23/882 ,  B01J23/883 ,  B01J23/8993 ,  B01J35/002 ,  B01J37/033 ,  C10G45/08 ,  C10G65/02

Abstract: A high-activity hydrotreating catalyst containing a uniformly dispersed active component at a high concentration, and particularly useful for deep desulfurization of a hydrocarbon oil for its high hydrodesulfurization activity. The present invention also provides a hydrotreating process using the same catalyst.

Abstract translation: 高活性加氢处理催化剂含有高浓度均匀分散的活性组分，特别适用于高油加氢脱硫活性的烃油深度脱硫。 本发明还提供了使用相同催化剂的加氢处理方法。

公开(公告)号：US4833107A

公开(公告)日：1989-05-23

申请号：US253916

申请日：1988-10-04

Applicant: Hiroshi Kaya ,  Kozaburo Tamura ,  Takeshi Isoda

Inventor： Hiroshi Kaya ,  Kozaburo Tamura ,  Takeshi Isoda

IPC: C04B35/58 ,  C01B21/068 ,  C01B21/082 ,  C04B35/589 ,  D01F9/10

CPC classification number: C04B35/589

Abstract: Fired nitride-base ceramics, i.e., silicon nitride or oxynitride, having a low carbon content and, therefore, low electrical and thermal conductivities, can be produced by heat treating a ceramic precursor comprising polysilazane, polysiloxazane or polycarbosilazane or a mixture thereof as the main ingredient in a reducing atmosphere such as hydrogen, ammonia or a gas containing these components, followed by firing.

Abstract translation: 可以通过热处理包含聚硅氮烷，聚硅氧烷或聚碳硅氮烷或其混合物作为主要的陶瓷前体来生产具有低碳含量，因此具有低电导率和热导率的氮化硅基陶瓷，即氮化硅或氮氧化物 还原气氛如氢气，氨水或含有这些组分的气体，随后进行烧制。