公开(公告)号：US3966820A

公开(公告)日：1976-06-29

申请号：US581501

申请日：1975-05-30

申请人： Peter H. Nelson ,  Karl G. Untch

发明人： Peter H. Nelson ,  Karl G. Untch

IPC分类号： C07C69/007 ,  A61K31/12 ,  C07C45/00 ,  C07C49/747 ,  C07C49/753 ,  C07C49/755 ,  C07C51/09 ,  C07C51/377 ,  C07C51/493 ,  C07C63/331 ,  C07C63/66 ,  C07C67/00 ,  C07C49/76

CPC分类号： C07C63/66 ,  C07C49/747 ,  C07C49/755 ,  C07C51/09 ,  C07C51/377 ,  C07C51/493 ,  C07C63/331 ,  Y10S514/916

摘要： 2-Substituted-5-oxo-5H-dibenzo [a,d]cycloheptenes represented by the following formula: ##SPC1##Where one of R.sup.2 and R.sup.3 is hydrogen, and the other is hydrogen, methyl, or ethyl, or together R.sup.2 and R.sup.3 are methylene; the dotted line represents an optional, additional bond between the carbon atoms at the 10- and 11-positions; and the pharmaceutically acceptable esters and ethers thereof. The compounds have anti-inflammatory, analgesic, and antipyretic activities and, accordingly, are useful in the treatment of inflammation, pain and pyrexia.

摘要翻译： 2-取代的5-氧代-5H-二苯并[a，d]环庚烯，由下式表示：