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公开(公告)号：US20120197121A1
公开(公告)日：2012-08-02
申请号：US13444688
申请日：2012-04-11
摘要： A method and system for controlled thermal injury of human superficial tissue based on the ability to controllably create thermal lesions of variable shape, size, and depth via precise spatial and temporal control of acoustic energy deposition. The apparatus includes a control system and probes that facilitate treatment planning, control and delivery of energy, and monitoring of treatment conditions.
摘要翻译： 基于通过声能沉积的精确空间和时间控制可控制地产生可变形状，大小和深度的热损伤的能力，人体表面组织受控热损伤的方法和系统。 该装置包括一个控制系统和探头，便于治疗计划，能量的控制和传递以及治疗条件的监测。
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公开(公告)号：US20120165848A1
公开(公告)日：2012-06-28
申请号：US13136542
申请日：2011-08-02
IPC分类号： A61B17/32
CPC分类号： A61N7/00 , A61B8/13 , A61B8/14 , A61B8/4254 , A61B8/4272 , A61B8/485 , A61B8/5246 , A61B2017/320069 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N7/02 , A61N2007/0013 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments provide systems and methods of treating damaged cartilage. In some embodiments, a method can include targeting the damaged cartilage in region of interest, directing therapeutic ultrasound energy to the damaged cartilage, ablating at least a portion of the damaged cartilage and improving the damaged cartilage. The method can include focusing therapeutic ultrasound energy to create at least one lesion in a portion of the damaged cartilage. The method can also include imaging the damaged cartilage. The method can include increasing blood perfusion to the region of interest. The method can include welding together the damaged cartilage with therapeutic ultrasound energy. The method can include cutting the damaged cartilage and removing it from the joint with therapeutic ultrasound energy. The method can include smoothing the cartilage with therapeutic ultrasound energy. The method can include regenerating cartilage.
摘要翻译： 各种实施方案提供了治疗损伤软骨的系统和方法。 在一些实施方案中，一种方法可以包括在感兴趣的区域中靶向损伤的软骨，将治疗性超声能量引导到损伤的软骨，烧蚀至少一部分损坏的软骨并改善损坏的软骨。 该方法可以包括聚焦治疗超声能量以在损伤的软骨的一部分中产生至少一个病变。 该方法还可以包括成像损伤的软骨。 该方法可以包括增加对感兴趣区域的血液灌注。 该方法可以包括用受治疗的超声能量将损伤的软骨焊接在一起。 该方法可以包括切割受损的软骨，并用治疗超声能量从关节中去除它。 该方法可以包括用治疗性超声能量平滑软骨。 该方法可以包括再生软骨。
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53.发明申请Systems and methods for treating acute and/or chronic injuries in soft tissue 审中-公开用于治疗软组织急性和/或慢性损伤的系统和方法公开(公告)号：US20120165668A1
公开(公告)日：2012-06-28
申请号：US13136538
申请日：2011-08-02
CPC分类号： A61N7/00 , A61B8/13 , A61B8/14 , A61B8/4254 , A61B8/4272 , A61B8/485 , A61B8/5246 , A61B2017/320069 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N7/02 , A61N2007/0013 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments provide a method of treating fibrous soft tissue. The method can include the steps of targeting injured fibrous soft tissue located at or near an injury location; directing therapeutic ultrasound energy to the injured fibrous soft tissue; creating a conformal region of elevated temperature in the injured fibrous soft tissue; and creating at least one thermally induced biological effect in the injured fibrous soft tissue. In various embodiments the thermally induced biological effect can be one of coagulation, increased perfusion, reduction of inflammation, generation of heat shock proteins, and initiation of healing cascade.
摘要翻译： 各种实施方案提供了处理纤维软组织的方法。 该方法可以包括将位于损伤位置处或附近的损伤的纤维软组织靶向的步骤; 将治疗性超声能量指向损伤的纤维软组织; 在损伤的纤维软组织中产生高温保形区域; 并在损伤的纤维软组织中产生至少一种热诱导的生物效应。 在各种实施方案中，热诱导的生物效应可以是凝血，增加灌注，减少炎症，产生热休克蛋白，以及起始愈合级联之一。
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公开(公告)号：US20110172530A1
公开(公告)日：2011-07-14
申请号：US13071298
申请日：2011-03-24
CPC分类号： A61B8/4263 , A61B8/00 , A61B8/42 , A61B8/4245 , A61B8/4427 , A61B8/463
摘要： A non-invasive visual imaging system is provided, wherein the imaging system procures an image of a transducer position during diagnostic or therapeutic treatment. In addition, the system suitably provides for the transducer to capture patient information, such as acoustic, temperature, or ultrasonic images. For example, an ultrasonic image captured by the transducer can be correlated, fused or otherwise combined with the corresponding positional transducer image, such that the corresponding images represent not only the location of the transducer with respect to the patient, but also the ultrasonic image of the region of interest being scanned. Further, a system is provided wherein the information relating to the transducer position on a single patient may be used to capture similar imaging planes on the same patient, or with subsequent patients. Moreover, the imaging information can be effectively utilized as a training tool for medical practitioners.
摘要翻译： 提供一种非侵入式视觉成像系统，其中成像系统在诊断或治疗治疗期间获取换能器位置的图像。 此外，系统适当地提供换能器以捕获诸如声学，温度或超声波图像之类的患者信息。 例如，由换能器拍摄的超声波图像可以与相应的位置传感器图像相关联，融合或以其他方式组合，使得相应的图像不仅表示换能器相对于患者的位置，而且还代表 正在扫描感兴趣的区域。 此外，提供了一种系统，其中与单个患者上的换能器位置有关的信息可用于捕获同一患者或随后患者的类似成像平面。 此外，成像信息可以有效地用作医生的训练工具。
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55.发明申请公开(公告)号：US20110040184A1
公开(公告)日：2011-02-17
申请号：US12915358
申请日：2010-10-29
IPC分类号： A61B8/14
CPC分类号： A61B8/08 , A61B8/12 , A61B8/14 , A61B8/4488 , A61B8/5207 , A61B8/5238 , A61B8/5276 , A61B10/0233 , A61B17/22012 , A61B17/2202 , A61B17/29 , A61B17/320092 , A61B2090/378 , A61B2090/3784 , A61B2090/3929 , A61B2090/3975 , A61N7/022 , A61N2007/0078 , G01S15/899
摘要： A method for ultrasound imaging of anatomical tissue. A first signal is received from a first imaging ultrasound wave which has been reflected from a location in the anatomical tissue during a first time period. A second signal is received from a second imaging ultrasound wave which has been reflected from the location in the anatomical tissue during a later second time period, following a discrete medical treatment. The second signal is subtracted from the first signal to form a difference signal. The difference signal may be scaled, spatially filtered, then used to generate an indication, the indication showing the effect of the medical treatment in the location in the anatomical tissue.
摘要翻译： 解剖组织超声成像的方法。 从第一时间段内从解剖组织中的位置反射的第一成像超声波接收第一信号。 在离散的医疗处理之后，在稍后的第二时间段内已经从解剖组织中的位置反射的第二成像超声波接收第二信号。 从第一信号中减去第二信号以形成差分信号。 差分信号可以被缩放，空间过滤，然后用于产生指示，该指示表示在解剖组织中的位置处的医疗的影响。
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公开(公告)号：US20100312150A1
公开(公告)日：2010-12-09
申请号：US12857653
申请日：2010-08-17
IPC分类号： A61N7/00
CPC分类号： A61N7/022 , A61N2007/0065 , A61N2007/0078 , A61N2007/0095 , A61N2007/027
摘要： A system and method for medical treatment of tissue using ultrasound. The system comprises a probe having an array of transducer elements, an ultrasound waveform generator adapted to generate at least one electrical ultrasound signal, and a plurality of phase controls, each coupled to the ultrasound waveform generator and adapted to generate from the electrical ultrasound signal a phase-shifted drive signal that is coupled to an associated transducer element. The drive signal is effective to control grating lobe foci emitted by the array. The method employs the system.
摘要翻译： 一种使用超声波治疗组织的系统和方法。 该系统包括具有换能器元件阵列的探头，适于产生至少一个电超声波信号的超声波波形发生器和多个相位控制器，每个相位控制器耦合到超声波波形发生器，并适于从电超声信号a 耦合到相关联的换能器元件的相移驱动信号。 驱动信号有效地控制阵列发射的光栅叶片焦点。 该方法采用该系统。
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公开(公告)号：US20100241035A1
公开(公告)日：2010-09-23
申请号：US12792934
申请日：2010-06-03
IPC分类号： A61N7/00
CPC分类号： A61B17/320068 , A61B8/00 , A61H23/0245 , A61N7/02 , A61N2007/0034 , A61N2007/0052
摘要： A non-invasive ultra-high frequency ultrasound treatment method and system are provided. An exemplary method and system comprise a high-frequency ultrasound transducer system configured for providing ultrasound treatment to a patient such that the superficial and/or subcutaneous regions of the patient can be treated. An exemplary high-frequency ultrasound transducer system comprises a control system and a transducer configured to provide treatment to the superficial and/or subcutaneous regions of interest. The high-frequency ultrasound transducer may be configured to operate at higher frequencies and controlled power levels to provide treatment to the superficial and/or subcutaneous regions of interest. For example, higher frequencies within the range from approximately 20 MHz to 500 MHz or more may be utilized.
摘要翻译： 提供了非侵入式超高频超声处理方法和系统。 示例性方法和系统包括被配置为向患者提供超声治疗使得可以治疗患者的浅表和/或皮下区域的高频超声换能器系统。 示例性的高频超声换能器系统包括控制系统和被配置为向感兴趣的表面和/或皮下区域提供治疗的换能器。 高频超声换能器可以被配置为在更高的频率和受控的功率水平下操作以对感兴趣的表面和/或皮下区域提供治疗。 例如，可以使用在大约20MHz至500MHz或更大的范围内的较高频率。
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公开(公告)号：US07695436B2
公开(公告)日：2010-04-13
申请号：US10850959
申请日：2004-05-21
申请人： T. Douglas Mast , Peter G. Barthe , Paul M. Jaeger , Waseem Faidi , Stephen P. Leonard , Michael H. Slayton
发明人： T. Douglas Mast , Peter G. Barthe , Paul M. Jaeger , Waseem Faidi , Stephen P. Leonard , Michael H. Slayton
IPC分类号： A61B8/00
CPC分类号： G10K11/348 , G01S7/52047
摘要： A system for temporal transmit apodization of an ultrasound transducer array. The system includes a waveform generator and an ultrasound transducer array having a plurality of transducer elements. Each of the transducer elements is driven by a signal generator that generates a periodic waveform. The duty cycle of each signal generator is determined by a predetermined setting of a duty cycle control. The duty cycle of each signal generator is calculated to achieve a desired beam profile of the transducer array, such as acoustic focusing for reducing the level of grating lobes and side lobes. Apodization is achieved by varying the effective amplitude at each array element by varying the duty cycle of the signal provided to each element.
摘要翻译： 一种用于超声换能器阵列的时间发射变迹的系统。 该系统包括具有多个换能器元件的波形发生器和超声换能器阵列。 每个换能器元件由产生周期波形的信号发生器驱动。 每个信号发生器的占空比由占空比控制的预定设置确定。 计算每个信号发生器的占空比以实现换能器阵列的期望的波束分布，例如用于降低光栅瓣和旁瓣的水平的声聚焦。 通过改变提供给每个元件的信号的占空比来改变每个阵列元件的有效幅度来实现变迹。
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公开(公告)号：US20100011236A1
公开(公告)日：2010-01-14
申请号：US12509254
申请日：2009-07-24
IPC分类号： G06F1/26
CPC分类号： G06F1/263 , A61B2560/0214 , G06F1/266
摘要： A method and system for enhancing computer peripheral safety is provided. In accordance with various aspects of the present invention, the exemplary method and system are configured to monitor and/or isolate alternating current (A.C.) supplies with and/or from any peripheral subsystems or devices. An exemplary method and system comprises an A.C. supply, a host computer system, and a peripheral subsystem or device connected to the host computer system, such as an ultrasound imaging and/or therapy peripheral, and an isolation subsystem configured for monitoring and/or isolating the A.C. supply from the peripheral subsystem or device. In accordance with an exemplary embodiment, an isolation subsystem comprises application software and associated modules and functions that when executed continuously monitors and/or polls the host computer's hardware and/or operating system for the presence of an isolated source, such as a battery, or an unisolated power source, such as through a battery charger and/or other connection path to the A.C. main supply. In accordance with other exemplary embodiments, an isolation subsystem can comprises a wireless or other safe/isolated electrical link for connecting a patient contact device, and/or a verification link or other verification mechanisms configured between an isolation transformer and host computer to monitor or observe usage to power the host computer and peripheral subsystem.
摘要翻译： 提供了一种增强计算机外围安全性的方法和系统。 根据本发明的各个方面，示例性方法和系统被配置为监视和/或隔离具有和/或来自任何外围子系统或设备的交流（A.C.）电源。 示例性方法和系统包括AC电源，主计算机系统以及连接到主计算机系统的外围子系统或设备，诸如超声成像和/或治疗外围设备，以及被配置用于监测和/或隔离的隔离子系统 来自外围子系统或设备的AC电源。 根据示例性实施例，隔离子系统包括应用软件和相关联的模块和功能，当执行连续地监视和/或轮询主计算机的硬件和/或操作系统以存在诸如电池的隔离源的存在时，或 非隔离电源，例如通过电池充电器和/或到AC主电源的其它连接路径。 根据其他示例性实施例，隔离子系统可以包括用于连接患者接触装置的无线或其他安全/隔离的电气连接和/或配置在隔离变压器和主计算机之间的验证链路或其他验证机制以监视或观察 用于为主机和外围子系统供电。
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公开(公告)号：US20090182231A1
公开(公告)日：2009-07-16
申请号：US12350383
申请日：2009-01-08
CPC分类号： A61N7/02 , A61B5/682 , A61B5/6842 , A61B8/08 , A61B8/0858 , A61B8/12 , A61B8/13 , A61B8/4209 , A61B8/4281 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B8/546 , A61B2017/320069 , A61H23/0245 , A61H2201/5007 , A61N7/00 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/027 , G01S15/8909
摘要： A method and system for ultrasound treatment of acne and sebaceous glands are provided. An exemplary method and system are configured for targeted treatment of sebaceous glands in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound at various spatial and temporal energy settings. An exemplary method and system can be configured to produce regions of heating and damage by destroying the function of sebaceous glands within a user-specified treatment layer depth associated with the glands to be treated. In addition, an exemplary method and system can be configured to produce regions of heating and damage within the treatment layer in spatially defined patterns, rather than heating and destroying the entire volume of the target layer of tissue. Further, an exemplary method and system can be configured to specifically aim such regions of heating and damage within the treatment layer, to occur at the same location as the secretory portion of sebaceous glands.
摘要翻译： 提供了一种超声治疗痤疮和皮脂腺的方法和系统。 一种示例性方法和系统被配置为以各种方式对皮脂腺进行靶向治疗，例如仅通过使用治疗，治疗和监测，成像和治疗，或治疗，成像和监测，和/或通过使用集中的，未聚焦的 ，或在各种空间和时间能量设置的散焦超声波。 示例性方法和系统可以被配置为通过在与待治疗的腺体相关联的用户指定的治疗层深度内破坏皮脂腺的功能来产生加热和损伤的区域。 此外，示例性方法和系统可以被配置为在空间限定的图案中产生处理层内的加热和损坏区域，而不是加热和破坏组织的目标层的整个体积。 此外，示例性方法和系统可以被配置为特别地将处理层内的这种加热和损伤区域瞄准在与皮脂腺的分泌部分相同的位置处。
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