公开(公告)号：US10722550B2

公开(公告)日：2020-07-28

申请号：US16250612

申请日：2019-01-17

Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE ,  ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY

Inventor： David Engelthaler ,  Elizabeth Driebe ,  Hongwei “Holly” Yin ,  Michael Valentine ,  Donald Chow ,  Jolene Bowers ,  Paul Keim ,  Bridget Barker

IPC: A61K31/41 ,  A61K31/135 ,  A61K38/13 ,  A61K31/7135 ,  A61K31/58 ,  A61K31/5377 ,  A61K31/5415 ,  A61K31/4196 ,  A61K31/496 ,  A61K31/495 ,  A61K45/06 ,  A61K31/138 ,  A61K31/277 ,  A61K31/353 ,  A61K31/404 ,  A61K31/4174 ,  A61K31/428 ,  A61K31/4741 ,  A61K31/609

Abstract: The present invention comprises methods of treating an infection using a pharmaceutical composition comprising an active ingredient selected from Table 1. In some aspects, the infection can be caused by one or more pathogens, including fungal pathogens. For example, the infection may be Valley Fever.

公开(公告)号：US20190352702A1

公开(公告)日：2019-11-21

申请号：US16283232

申请日：2019-02-22

Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE ,  ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY

Inventor： Jolene Bowers ,  Elizabeth Driebe ,  David Engelthaler ,  Paul Keim

IPC: C12Q1/689

Abstract: Embodiments of the invention provide a method of detecting one or more strains of Klebsiella pneumoniae. The method may include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the K. pneumonia genome that can provide definitive information to distinguish between one or more types or strains of K. pneumonia.

公开(公告)号：US20170022543A1

公开(公告)日：2017-01-26

申请号：US15214709

申请日：2016-07-20

Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE ,  ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY

Inventor： Jolene Bowers ,  Elizabeth Driebe ,  David Engelthaler ,  Paul Keim

IPC: C12Q1/68

CPC classification number: C12Q1/689 ,  C12Q2600/16

Abstract: Embodiments of the invention provide a method of detecting one or more strains of Klebsiella pneumoniae. The method may include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the K. pneumonia genome that can provide definitive information to distinguish between one or more types or strains of K. pneumonia.

Abstract translation: 本发明的实施方案提供了检测肺炎克雷伯杆菌的一种或多种菌株的方法。 该方法可以包括形成用于核酸扩增的多种混合物。 该方法可以包括在肺炎支原体基因组内扩增特异性序列，其可以提供确定的信息来区分肺炎克雷伯杆菌的一种或多种类型或菌株。