公开(公告)号：US20100240993A1

公开(公告)日：2010-09-23

申请号：US12727357

申请日：2010-03-19

Applicant: Thorsten Bergsdorf ,  Christian Chaussy ,  Ralf Nanke ,  Stefan Thueroff

Inventor： Thorsten Bergsdorf ,  Christian Chaussy ,  Ralf Nanke ,  Stefan Thueroff

IPC: A61B8/00

CPC classification number: A61B5/145 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/4381 ,  A61B8/0833 ,  A61B17/22004 ,  A61N2007/0039 ,  G01N33/57407

Abstract: In a method and medical apparatus to determine a tumor characteristic related to a body region of a patient, the body region is exposed to acoustic energy that mechanically irritates the body region. A first value of a characteristic value of the patient that is correlated with the irritation is determined at a first point in time. A second value of the characteristic value is determined at a second point in time after the first point in time and after the exposure. The tumor characteristic is determined from the change between first value and second value.

Abstract translation: 在用于确定与患者的身体区域相关的肿瘤特征的方法和医疗装置中，身体区域暴露于机械刺激身体区域的声能。 在第一时间点确定与刺激相关的患者的特征值的第一值。 在第一时间点和曝光后的第二时间点确定特征值的第二值。 根据第一值和第二值之间的变化确定肿瘤特征。

公开(公告)号：US20090062645A1

公开(公告)日：2009-03-05

申请号：US12203198

申请日：2008-09-03

Applicant: Jens Fehre ,  Ralf Nanke ,  Martin Stetter

Inventor： Jens Fehre ,  Ralf Nanke ,  Martin Stetter

IPC: A61B8/13 ,  A61B5/00

CPC classification number: A61N7/00 ,  A61B5/055 ,  A61B5/4381 ,  A61B8/08

Abstract: In a method for diagnosis and treatment of a patient with a tumor relating to prostate cancer, the following steps are implemented. A differential diagnosis of prostate cancer versus prostatitis and/or BPH is conducted on a patient using a cost-effective diagnosis method. If prostate cancer is diagnosed in the patient using a cost-effective measurement method, a characteristic value for the tumor aggressiveness of the prostate cancer is determined. A watchful waiting treatment is implemented with the patient given a characteristic value below a predeterminable first limit value. The size and position of the tumor is determined using a cost-effective method given a characteristic value above the first limit value. A cost-effective ultrasonic theranosis or a conventional therapy is conducted for a size below a second predeterminable limit value. The presence of metastases in the patient is checked, with a cost-intensive method generating image information, for a size above the second limit value. A metastasis treatment is implemented in the event that metastases are present. In the event that no metastases are present, a tumor treatment based on the aforementioned image information generated is implemented.

Abstract translation: 在用于诊断和治疗患有与前列腺癌相关的肿瘤的患者的方法中，实施以下步骤。 使用成本效益的诊断方法对患者进行前列腺癌与前列腺炎和/或BPH的鉴别诊断。 如果使用成本有效的测量方法在患者中诊断前列腺癌，则确定前列腺癌的肿瘤侵袭性的特征值。 给予患者给予低于可预定的第一极限值的特征值的注意等待治疗。 使用给定特征值高于第一极限值的成本有效的方法确定肿瘤的大小和位置。 以低于第二预定极限值的尺寸进行成本有效的超声治疗或常规治疗。 检查患者中转移灶的存在，以成本密集型方法产生图像信息，尺寸高于第二限制值。 在存在转移的情况下实施转移治疗。 在不存在转移的情况下，实现基于上述生成的图像信息的肿瘤治疗。

公开(公告)号：US20090060847A1

公开(公告)日：2009-03-05

申请号：US12203193

申请日：2008-09-03

Applicant: Sueleyman Erguen ,  Jens Fehre ,  Ralf Nanke ,  Bernhard Singer ,  Derya Tilki

Inventor： Sueleyman Erguen ,  Jens Fehre ,  Ralf Nanke ,  Bernhard Singer ,  Derya Tilki

IPC: A61B8/08

CPC classification number: A61K49/223 ,  A61K49/225

Abstract: A contrast agent for ultrasound examination of the prostate has contrast-intensifying particles on an exterior of which at least one binding molecule is present that specifically binds to CEACAM-1. In a method for ultrasound examination of the prostate, such a contrast agent is administered to the patient and a sonography of the prostate is subsequently implemented.

Abstract translation: 用于前列腺超声检查的造影剂具有在其外部具有特异性结合CEACAM-1的至少一个结合分子的造影剂增强颗粒。 在用于前列腺超声检查的方法中，将这样的造影剂施用于患者，随后实施前列腺超声检查。