公开(公告)号：US11573411B2

公开(公告)日：2023-02-07

申请号：US17083659

申请日：2020-10-29

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： Noam Yorav-Raphael ,  Joseph Joel Pollak ,  Sarah Levy Schreier ,  Yochay Shlomo Eshel

IPC: G01N21/64 ,  G02B21/00 ,  G02B21/36

Abstract: Apparatus and methods for determining a property of a bodily sample using a microscope are described. A sample carrier includes a plurality of microscopy sample chambers configured to receive a least a portion of the bodily sample, while the sample is imaged by the microscope. Each of the microscopy sample chambers has an upper and a lower surface, and the microscopy sample chambers have respective heights between the upper and lower surfaces that are different from each other. The sample carrier defines a microscopy sample chamber inlet hole, that is fluid communication with all of the microscopy sample chambers, such as to facilitate filling of all of the microscopy sample chambers with the portion of the bodily sample, via the microscopy sample chamber inlet hole. Other applications are also described.

公开(公告)号：US20220128811A1

公开(公告)日：2022-04-28

申请号：US17568858

申请日：2022-01-05

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： Yochay Shlomo Eshel ,  Natalie Lezmy ,  Dan Gluck ,  Arnon Houri Yafin ,  Joseph Joel Pollak

IPC: G02B21/36 ,  G06V20/69 ,  G01N21/88 ,  G06T7/00

Abstract: Apparatus and methods are described for analyzing a bodily sample. A microscope system acquires one or more microscope images of the bodily sample. A computer processor identifies elements as being candidates of a given entity, in the one or more images. At least one sample-informative feature, relating to a characteristic of the candidates of the given entity in the sample as a whole, is extracted from the one or more images. A characteristic of the sample is determined at least partially based upon the sample-informative feature, and an output is generated in response thereto. Other applications are also described.

公开(公告)号：US11099175B2

公开(公告)日：2021-08-24

申请号：US16099270

申请日：2017-05-11

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： Amir Zait ,  Arnon Houri Yafin ,  Dan Gluck ,  Sharon Pecker ,  Yochay Shlomo Eshel ,  Sarah Levy Schreier ,  Joseph Joel Pollak

IPC: G01N33/49 ,  G01N33/50 ,  G01N33/72 ,  G01N15/05 ,  G01N15/06 ,  G01N33/569 ,  G01N15/00

Abstract: Apparatus and methods are described for use with a blood sample (48, 50), including measuring hemoglobin concentration within at least a portion (48) of the blood sample, by performing a first measurement on the blood sample. Mean corpuscular hemoglobin in the blood sample (48, 50) is measured, by performing a second measurement on the blood sample (48, 50). A parameter of the blood sample is determined, based on a relationship between the concentration of hemoglobin and the mean corpuscular hemoglobin. Other applications are also described.

公开(公告)号：US20210055533A1

公开(公告)日：2021-02-25

申请号：US17083775

申请日：2020-10-29

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： Noam Yorav-Raphael ,  Joseph Joel Pollak ,  Sarah Levy Schreier ,  Yochay Shlomo Eshel

IPC: G02B21/00 ,  G01N21/64 ,  G02B21/36

Abstract: Apparatus and methods are described for determining a property of a bodily sample using a microscope and optical-density-measurement apparatus, the apparatus including a sample carrier that includes a plurality of microscopy sample chambers configured to receive a first portion of the sample and to facilitate imaging of the first portion of the sample by the microscope, each of the microscopy sample chambers having an upper and a lower surface, and having respective heights between the upper and lower surfaces that are different from each other. The sample carrier includes at least one optical-density-measurement chamber configured to receive a second portion of the sample, and to facilitate optical density measurements being performed optical-density-measurement apparatus upon the second portion of the sample. Other applications are also described.

公开(公告)号：US20210041417A1

公开(公告)日：2021-02-11

申请号：US17083647

申请日：2020-10-29

Applicant: S.D. SIGHT DIAGNOSTICS LTD

Inventor： Joseph Joel Pollak ,  Sarah Levy Schreier ,  Yochay Shlomo Eshel ,  Amir Zait ,  Sharon Pecker ,  Trevor Ruggiero

IPC: G01N33/50 ,  G01N21/31 ,  G01N21/59 ,  G01N21/64 ,  G01N21/03

Abstract: Apparatus and methods are described for determining a property of a biological sample. A sample carrier includes a glass substrate configured to define a first surface of a sample chamber that is configured to receive the sample, and a plastic substrate configured to define a second surface of the sample chamber. The height of the sample chamber at each location within the sample chamber is defined by a gap between the first surface and the second surface. An adhesive adheres the glass substrate to the plastic substrate. The plastic substrate is shaped such that the sample chamber defines a first region and a second region, with the sample chamber defining a predefined variation in height between the first region and the second region. Other applications are also described.