公开(公告)号：US11475560B2

公开(公告)日：2022-10-18

申请号：US16778252

申请日：2020-01-31

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: G06T7/00 ,  G06T7/11 ,  G06T7/13 ,  A61B5/00 ,  A61B5/02 ,  G06T5/00

Abstract: In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as OCT, IVUS, or other imaging modalities. In one embodiment, a representation of A-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel. One or more operators such as filters can be applied to remove false positives associated with other detections.

公开(公告)号：US20220280261A1

公开(公告)日：2022-09-08

申请号：US17750978

申请日：2022-05-23

Applicant: LightLab Imaging, Inc.

Inventor： James Booker ,  David Ellman ,  Douglas Tatosian ,  Charles Milne

IPC: A61B90/00 ,  A61B5/00

Abstract: In one embodiment, the disclosure relates to a probe that a cylindrical marker band defining an inner surface, an outer surface, a first end and a second end and having a band length, the inner surface defining a marker band bore, the cylindrical marker band includes a radiopaque material; a molded unitary lens defining an elongate optical fiber receiving section having a fiber section length and a beam directing surface, wherein the fiber section length and the band length overlap along an overlap distance; and an optical fiber, wherein a first section of the optical fiber is disposed in the optical fiber receiving section, wherein a portion of the first section of the optical fiber is disposed within the marker band bore.

公开(公告)号：US20220260360A1

公开(公告)日：2022-08-18

申请号：US17666726

申请日：2022-02-08

Applicant: LightLab Imaging, Inc.

Inventor： Chih-Hao Liu ,  Steven M. Stromski

IPC: G01B9/02091 ,  G01B9/02055 ,  G01B9/02

Abstract: Aspects of the disclosure relate to systems, methods, and algorithms to perform wavenumber linearization and dispersion correction in optical systems without the need for hardware modifications, empirical adjustments, precise mirror alignment, and which can be conducted at low computational costs and in real-time. A one-time calibration process can generate spectra or calibration criteria, including wavenumber-linearization criteria, dispersion correction, and spectral flattening spectra, which can be used to correct an optical coherence tomogram in real time.

公开(公告)号：US11344373B2

公开(公告)日：2022-05-31

申请号：US16425709

申请日：2019-05-29

Applicant: LIGHTLAB IMAGING, INC.

Inventor： Ajay Gopinath ,  Kyle Savidge ,  Robert Steinbrecher

IPC: A61B5/00 ,  A61B34/20 ,  A61B34/00 ,  A61B90/00 ,  A61B5/021 ,  A61B5/026 ,  A61B6/12 ,  A61B6/00 ,  A61B8/08 ,  A61F2/95 ,  A61B34/10

Abstract: In part, the disclosure relates to systems and methods to assess stent/scaffold expansion in a vessel on an expedited time scale after stent/scaffold placement and expansion. In one embodiment, the method generates a first representation of a stented segment of the blood vessel indicative of a level of stent expansion; determines using the detected stent struts, a first end of the stent and a second end of the stent; and generate a second representation of the segment of the blood vessel by interpolating a lumen profile using an offset distance from the first end and the second end.

公开(公告)号：US11287961B2

公开(公告)日：2022-03-29

申请号：US16444319

申请日：2019-06-18

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Denis Dion ,  Christopher E. Griffin ,  Desmond Adler

IPC: G06F3/048 ,  G06F3/04847 ,  A61B34/10 ,  A61B5/00 ,  A61B34/20 ,  A61B8/12 ,  G06T15/08 ,  G06T7/00 ,  G06T19/00 ,  G06F3/04815 ,  A61B5/02 ,  G16H30/40 ,  G16H50/20 ,  G16H20/40

Abstract: In part, the disclosure relates to intravascular data collection systems and the software-based visualization and display of intravascular data relating to detected side branches and detected stent struts. Levels of stent malapposition can be defined using a user interface such as a slider, toggle, button, field, or other interface to specify how indicia are displayed relative to detected stent struts. In addition, the disclosure relates to methods to automatically provide a two or three-dimensional visualization suitable for assessing side branch and/or guide wire location during stenting. The method can use one or more a computed side branch location, a branch takeoff angle, one or more stent strut locations, and one or more lumen contours.

公开(公告)号：US11250294B2

公开(公告)日：2022-02-15

申请号：US16741718

申请日：2020-01-13

Applicant: LightLab Imaging, Inc.

Inventor： Shimin Li ,  Ajay Gopinath ,  Kyle Savidge

IPC: G06K9/62 ,  G06N3/04 ,  G06N3/08

Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

公开(公告)号：US20210082121A1

公开(公告)日：2021-03-18

申请号：US17084805

申请日：2020-10-30

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Desmond Adler

IPC: G06T7/13 ,  A61B5/02 ,  G06T5/50 ,  G06T7/12 ,  G06T11/60 ,  G06T19/20 ,  A61B5/00

Abstract: In part, the disclosure relates to method for identifying regions of interest in a blood vessel. The method includes the steps of: providing OCT image data of the blood vessel; applying a plurality of different edge detection filters to the OCT image data to generate a filter response for each edge detection filter; identifying in each edge detection filter response any response maxima; combining the response maxima for each edge detection filter response while maintaining the spatial relationship of the response maxima, to thereby create edge filtered OCT data; and analyzing the edge filtered OCT data to identify a region of interest, the region of interest defined as a local cluster of response maxima. In one embodiment, one or more indicia are positioned in one or more panels to emphasize a reference vessel profile as part of a user interface.

公开(公告)号：US10792012B2

公开(公告)日：2020-10-06

申请号：US13758591

申请日：2013-02-04

Applicant: LightLab Imaging, Inc.

Inventor： Christopher Hutchins ,  Michael Atlas ,  Alexander Ship

IPC: A61B8/00 ,  A61B5/00 ,  A61B8/12

Abstract: In one aspect, the invention relates to one or more rotatable elements and one or more stationary element such that the elements are arranged along a common axis of rotation co-linear with or substantially parallel to an optical path. The optical path is a portion of a sample arm of an interferometer. Further, the rotatable and stationary elements are configured to couple electrical signals and optical signals between a data collection probe and an interface unit or other component of an imaging system. In one embodiment, the data collection probe is a combination ultrasound and OCT probe. In one aspect, the invention relates to a rotary joint in which the optical fiber and a fiber optic rotary joint lie in the center of one or more conductive elements of an electrical rotary joint which are annularly disposed around one or both of the optical fiber and optical rotary joint.

公开(公告)号：US20200226422A1

公开(公告)日：2020-07-16

申请号：US16741718

申请日：2020-01-13

Applicant: LightLab Imaging, Inc.

Inventor： Shimin Li ,  Ajay Gopinath ,  Kyle Savidge

IPC: G06K9/62 ,  G06N3/08 ,  G06N3/04

Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

公开(公告)号：US20190380594A1

公开(公告)日：2019-12-19

申请号：US16549814

申请日：2019-08-23

Applicant: LIGHTLAB IMAGING, INC.

Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

IPC: A61B5/02 ,  A61B5/00

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.