Abstract:
An apparatus for testing of electrical or physical properties of a material include a single coil sensor mounted adjacent to a sample of the material. Sheet conductance of a wide variety of materials may be measured using the single coil to determine if the material conforms to generally accepted standards for the use to which the material will be put. In some examples, the material is a semiconductor wafer or flat panel. In other examples, the material is the body tissue of a patient. A non-invasive technique using the apparatus is also disclosed for monitoring the health of patient tissue such as musculature, and/or to determine whether healthy circulation is present, by measuring the conductance of the patient tissue in response to a magnetic field applied by the single coil. The single coil may be hand held, or it may be movable using an automated positioning system under computer control.
Abstract:
A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.
Abstract:
A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.
Abstract:
An apparatus for testing of electrical or physical properties of a material include a single coil sensor mounted adjacent to a sample of the material. Sheet conductance of a wide variety of materials may be measured using the single coil to determine if the material conforms to generally accepted standards for the use to which the material will be put. In some examples, the material is a semiconductor wafer or flat panel. In other examples, the material is the body tissue of a patient. A non-invasive technique using the apparatus is also disclosed for monitoring the health of patient tissue such as musculature, and/or to determine whether healthy circulation is present, by measuring the conductance of the patient tissue in response to a magnetic field applied by the single coil. The single coil may be hand held, or it may be movable using an automated positioning system under computer control.
Abstract:
A device for measuring an electrical impedance of biologic tissue may include electrodes configured to contact the biologic tissue and generate a differential voltage thereon. The device may include a first circuit coupled to the electrodes and configured to force an oscillating input signal therethrough, and a differential amplitude modulation (AM) demodulator coupled to the plurality of electrodes. The differential AM demodulator may be configured to demodulate the differential voltage, and generate a base-band signal representative of the demodulated differential voltage. The device may further include an output circuit downstream from the differential AM demodulator and may be configured to generate an output signal representative of the electrical impedance as a function of the base-band signal.
Abstract:
Systems and methods for determining a concentration of biodiesel in a mixture of biodiesel and petrodiesel are provided. In one exemplary embodiment, a method includes receiving an oscillatory signal at an inductance-capacitance-resistance circuit. The circuit has a sensing element fluidly communicating with the mixture of biodiesel and petrodiesel. The method further includes generating a resonant current at a resonant frequency utilizing the circuit in response to the oscillatory signal. The method further includes determining a concentration value indicating the concentration of the biodiesel in the mixture based on an amplitude of the resonant current and/or the resonant frequency, utilizing a microprocessor. The method further includes storing the concentration value in a memory device, utilizing the microprocessor.
Abstract:
The present invention is directed to devices and methods for carrying out and/or monitoring biological reactions in response to electrical stimuli. A programmable multiplexed active biologic array includes an array of electrodes coupled to sample-and-hold circuits. The programmable multiplexed active biologic array includes a digital interface that allows external control of the array using an external processor. The circuit may monitor, digitally control, and deliver electrical stimuli to the electrodes individually or in selected groups.
Abstract:
A self-contained autonulling bridge circuit based on phase-sensitive deteon of an impedance to be measured is described. The system utilizes a feedback structure to control a variable impedance in order to establish the null of the bridge. The system utilizes a voltage-variable impedance having both resistance and capacitance and provides the phase sensitive relationship in the control means in order to provide highly accurate measurement of an unknown test impedance. The ability to measure small changes in impedance provides particularly useful application to the area of biological sensor impedance measurement or electrochemical impedance measurement using silicon-based devices.
Abstract:
An electrical bridge circuit for measuring a given parameter of an electrical element such as a resistor, inductor, or capacitor comprises a pair of power-supply input terminals and a first pair of bridge arms connected across the input terminals to establish a point of fixed intermediate potential. The bridge circuit further includes a second pair of bridge arms connected in series across the terminals, the first arm initially effectively including only terminals for connection to the electrical element to be measured. A control circuit is connected between the point of intermediate potential and the junction of the first and second arms. The bridge circuit includes a series of reference electrical elements having parameters of the type to be measured, for example resistance, of values progressing in approximately a geometric series, and the second bridge arm initially includes a plurality of such reference elements having a total parametric value greater than the largest value to be measured. The circuit further includes means responsive to an electrical output of the control circuit of only a given polarity for sequentially and selectively including in the second bridge arm reference elements of alternate parametric values in the series, commencing with the reference element of highest parametric value, and for selectively including one or more of the other reference elements in the first bridge arm, thereby progressively to reduce the arithmetic difference between the total parametric values of the electrical elements in the two bridge arms. The means for changing the circuit relationships of the reference elements as described includes a plurality of switching relays individually connected to switch the reference elements in or out of one or the other of the bridge arms, a selector switch effective to energize the relays in sequence, a plurality of holding relays for individually maintaining their energization and the energization of the switching relays, and a second selector switch effective to energize the holding relays in sequence.