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公开(公告)号：US12036055B2
公开(公告)日：2024-07-16
申请号：US17734311
申请日：2022-05-02
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Wenxiang Cong , Yan Xi
CPC classification number: A61B6/4042 , A61B6/032 , A61B6/405 , A61B6/482
Abstract: Systems and method for performing X-ray computed tomography (CT) that can improve spectral separation and decrease motion artifacts without increasing radiation dose are provided. The systems and method can be used with either a kVp-switching source or a single-kVp source. When used with a kVp-switching source, an absorption grating and a filter grating can be disposed between the X-ray source and the sample to be imaged. Relative motion of the filter and absorption gratings can by synchronized to the kVp switching frequency of the X-ray source. When used with a single-kVp source, a combination of absorption and filter gratings can be used and can be driven in an oscillation movement that is optimized for a single-kVp X-ray source. With a single-kVp source, the absorption grating can also be omitted and the filter grating can remain stationary.
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公开(公告)号：US20240036135A1
公开(公告)日：2024-02-01
申请号：US18228064
申请日：2023-07-31
Applicant: Rensselaer Polytechnic Institute
Inventor： Xun Jia , Ge Wang , Mengzhou Li , Weiwen Wu , Wenxiang Cong , Yuting Peng , Jace Grandinetti
IPC: G01R33/48 , G01R33/385
CPC classification number: G01R33/4812 , G01R33/385
Abstract: In one embodiment, there is provided a magnetic resonance (MR) subsystem for magnetic resonance imaging (MRI). The MR subsystem includes a first magnet-coil assembly and a second magnet-coil assembly. The first magnet-coil assembly includes a first magnet structure and a first gradient coil. The second magnet-coil assembly includes a second magnet structure and a second gradient coil. The first magnet-coil assembly and the second magnet-coil assembly are separated by a gap. The gap is configured to facilitate transmission of an x-ray beam from an x-ray source to an x-ray detector. The x-ray source and the x-ray detector are included in a computed tomography (CT) subsystem.
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公开(公告)号：US11592406B2
公开(公告)日：2023-02-28
申请号：US17711171
申请日：2022-04-01
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Guang Li , Wenxiang Cong
IPC: G01N23/201 , G01N23/20008 , A61B6/00
Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementary second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the gratings are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.
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公开(公告)号：US20220221413A1
公开(公告)日：2022-07-14
申请号：US17711171
申请日：2022-04-01
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Guang Li , Wenxiang Cong
IPC: G01N23/20008 , G01N23/201 , G21K1/02 , A61B6/03 , G01N23/046
Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementary second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the gratings are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.
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公开(公告)号：US10970886B2
公开(公告)日：2021-04-06
申请号：US16597250
申请日：2019-10-09
Applicant: University of Iowa Research Foundation , Shandong University , Shandong Provincial Chest Hospital , Rensselaer Polytechnic Institute
Inventor： Wenxiang Cong , Ye Yangbo , Ge Wang , Shuwei Mao , Yingmei Wang
Abstract: The disclosed apparatus, systems and methods relate to a framelet-based iterative algorithm for polychromatic CT which can reconstruct two components using a single scan. The algorithm can have various steps including a scaled-gradient descent step of constant or variant step sizes; a non-negativity step; a soft thresholding step; and a color reconstruction step.
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Patent Agency Ranking
公开(公告)号：US10548543B2
公开(公告)日：2020-02-04
申请号：US15538376
申请日：2015-12-22
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Yan Xi , Wenxiang Cong , Zaifeng Shi
Abstract: Novel and advantageous methods and systems for performing spectral computed tomography are provided. An edge-on detector, such as a silicon strip detector, can be used to receive X-rays after passing through a sample to be imaged. An energy resolving process can be performed on the collected X-ray radiation. The CT scanner can have third-generation or fourth-generation geometry.
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公开(公告)号：US10537299B2
公开(公告)日：2020-01-21
申请号：US15579394
申请日：2016-06-06
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Qingsong Yang , Wenxiang Cong
Abstract: Systems and methods for determining an attenuation sinogram for a time-of-flight (TOF) positron emission tomography (PET) scan using only TOF PET data, and including use of the total amount of tracer provided to the subject of the TOF PET scan, are provided. The total amount of injected tracer can be used to determine the otherwise unknown constant shift present when an attenuation sinogram is estimated using the gradient of the attenuation sinogram. The attenuation sinogram can therefore be accurately and stably determined without any additional knowledge on the attenuation sinogram or map.
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公开(公告)号：US12151002B2
公开(公告)日：2024-11-26
申请号：US15305510
申请日：2015-04-21
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Matthew Webber Getzin , Lars Arne Gjesteby , Wenxiang Cong
Abstract: Imaging systems and methods are provided. Systems and methods of the subject invention can include the use of nanoparticles (for example, nanophosphors) within a sample to be imaged. Excitation with radiation, such X-ray radiation, can be performed on the nanoparticles to give rise to a change in one or more resonance parameters of the nanoparticles, and this change can be measured using magnetic resonance imaging to provide localization information.
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公开(公告)号：US12000916B2
公开(公告)日：2024-06-04
申请号：US17279400
申请日：2019-03-13
Applicant: Rensselaer Polytechnic Institute
Inventor： Ge Wang , Lars Arne Gjesteby , Wenxiang Cong
CPC classification number: G01R33/481 , A61B6/037 , A61B6/4258 , A61B6/4417 , A61B6/5235 , G01R33/0385 , G01R33/38
Abstract: A simultaneous emission-transmission tomography in an MRI hardware framework is described. A method of multimodality imaging includes reconstructing, by a simultaneous emission transmission (SET) circuitry, a concentration image based, at least in part, on a plurality of selected γ-rays; and reconstructing, by the SET circuitry, an attenuation image based, at least in part, on the plurality of selected γ-rays. The plurality of selected γ-rays is emitted by a polarized radio tracer included in a test object. The selected γ-rays are selected based, at least in part, on a radio frequency (RF) pulse and based, at least in part, on a gradient magnetic field.
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40.发明授权公开(公告)号：US11850081B2
公开(公告)日：2023-12-26
申请号：US17460470
申请日：2021-08-30
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Wenxiang Cong
IPC: G06T11/00 , A61B6/03 , G06N3/04 , G06V10/764 , G06V10/774 , G06V10/60
CPC classification number: A61B6/032 , G06N3/04 , G06T11/006 , G06V10/60 , G06V10/764 , G06V10/774 , G06T2207/10081 , G06T2207/20081 , G06T2207/20084
Abstract: A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening.
An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.
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