公开(公告)号：US20210299112A1

公开(公告)日：2021-09-30

申请号：US17099759

申请日：2020-11-16

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: A61K31/4436 ,  A61K31/415 ,  A61K45/06 ,  A61K31/4155 ,  C07D409/12

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, cough, itch, and neurogenic inflammation.

公开(公告)号：US20210284610A1

公开(公告)日：2021-09-16

申请号：US17197508

申请日：2021-03-10

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: C07D223/04 ,  C07D207/06 ,  C07D211/14 ,  C07D225/02

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are particularly useful for the treatment of itch and other dermal conditions.

公开(公告)号：US20210128589A1

公开(公告)日：2021-05-06

申请号：US17090160

申请日：2020-11-05

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: A61K31/66 ,  A61K45/06 ,  C07F9/54 ,  C07F9/6568

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.

公开(公告)号：US10934263B2

公开(公告)日：2021-03-02

申请号：US16815803

申请日：2020-03-11

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: C07D241/12 ,  C07D213/04 ,  C07D233/61 ,  C07D237/08 ,  C07D471/04 ,  C07D401/04 ,  C07D231/12

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, cough, itch, and neurogenic inflammation.

公开(公告)号：US10925865B2

公开(公告)日：2021-02-23

申请号：US16936556

申请日：2020-07-23

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: A61K31/4425 ,  C07D213/80 ,  C07D213/04 ,  A61K45/06 ,  A61K31/415 ,  C07D231/12

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, cough, itch, and neurogenic inflammation.

公开(公告)号：US20200289490A1

公开(公告)日：2020-09-17

申请号：US16675982

申请日：2019-11-06

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: A61K31/452 ,  C07D223/04 ,  C07D225/02 ,  A61K31/40 ,  A61K31/55 ,  C07D207/06 ,  A61K45/06 ,  C07D211/14 ,  A61K31/395

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.

公开(公告)号：US20200289484A1

公开(公告)日：2020-09-17

申请号：US16676043

申请日：2019-11-06

Applicant: Nocion Therapeutics, Inc.

Inventor： Bridget McCarthy Cole ,  James Lamond Ellis

IPC: A61K31/4425 ,  C07D213/80 ,  A61K45/06 ,  C07D213/04

Abstract: The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, cough, itch, and neurogenic inflammation.