摘要:
A method for the treatment and/or prophylaxis of an ostenonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).
摘要:
A controlled release pharmaceutical composition comprising a strontium salt. The invention also relates to the use of a strontium salt for treating a male suffering from diseases and conditions affecting metabolism and/or structural integrity of cartilage and/or bone. The invention also relates to the use of a strontium-containing compound for preventing a cartilage and/or bone condition in a subject, and for the treatment and/or prophylaxis of secondary osteoporosis.
摘要:
An active filter (2) is connected to a dc circuit (L1, L2) in a converter (SR1) in an installation for transmission of high-voltage direct current. Control equipment (5) generates, in dependence on a control signal, a control order (SCF) for the active filter which, in dependence thereon, generates and supplies to the dc connection one of a filter voltage (UF) and a filter current (IF) for reducing at least one tone of a chosen tone frequency in a current (Id) in the dc connection. The control equipment comprises a controlling unit which forms a controller signal in dependence on a supplied current measurement value (IM) of the current in the dc connection, and an identification unit. The identification unit forms a first compensating parameter in dependence on the current measurement value and on an excitation signal generated by the control equipment and added to the control order. The control equipment forms the control signal in dependence on the controlling signal and the compensating parameter, which has been formed such that the sum thereof and of the phase shift for a transfer function from the control signal to the current measurement value at the chosen tone frequency is at least approximately equal to a preselected value.