公开(公告)号：US20180259657A1

公开(公告)日：2018-09-13

申请号：US15457558

申请日：2017-03-13

Applicant: General Electric Company

Inventor： Geng Fu ,  Xue Rui ,  Yannan Jin ,  Jianjun Guo ,  Peter Michael Edic ,  Brian David Yanoff

IPC: G01T1/24 ,  G01T1/36 ,  G01T7/00

CPC classification number: G01T1/247 ,  G01T1/241 ,  G01T1/366 ,  G01T7/005

Abstract: The present approach relates to the use of reference pixels provided between the primary pixels of a detector panel. Coincidence circuitry or logic may be employed so that the measured signal arising from the same X-ray event may be properly, that is the signal measured at both a reference and primary pixel may be combined so as to provide an accurate estimate of the measured signal, at an appropriate location on the detector panel.

公开(公告)号：US20170325770A1

公开(公告)日：2017-11-16

申请号：US15154637

申请日：2016-05-13

Applicant: General Electric Company

Inventor： Peter Michael Edic ,  Prem Venugopal ,  Darin Robert Okerlund

IPC: A61B6/00 ,  G06F19/00 ,  A61B8/06 ,  A61B6/03

Abstract: The present approach provides a non-invasive methodology for estimation of coronary flow and/or fractional flow reserve. In certain implementations, various approaches for personalizing blood flow models of the coronary vasculature are described. The described personalization approaches involve patient-specific measurements and do not assume or rely on the resting coronary flow being proportional to myocardial mass. Consequently, there are fewer limitations in using these approaches to obtain coronary flow and/or fractional flow reserve estimates non-invasively.

公开(公告)号：US20170212253A1

公开(公告)日：2017-07-27

申请号：US15004127

申请日：2016-01-22

Applicant: General Electric Company

Inventor： Geng Fu ,  Peter Michael Edic ,  Brian David Yanoff ,  Jianjun Guo ,  Xin Wang ,  Bruno Kristiaan Bernard De Man ,  Xue Rui ,  Yannan Jin

IPC: G01T1/24 ,  G01T1/20 ,  A61B6/03 ,  H01L27/146

CPC classification number: G01T1/247 ,  A61B6/032 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4291 ,  G01T1/17 ,  G01T1/2018 ,  H01L27/14658

Abstract: A detector panel is described having readout circuitry integrated with the photodetectors, such as in the light imager panel. The detector is useful in high spatial resolution and low-dose or low-signal imaging contexts and may be used in adaptive 2D binning configurations. Adaptive binning of detector elements may be accomplished using control logic and X-ray intensity detector circuitry capable of assessing an incident X-ray intensity and controlling binning of an associated group of detector elements.

公开(公告)号：US20170086761A1

公开(公告)日：2017-03-30

申请号：US14868826

申请日：2015-09-29

Applicant: General Electric Company

Inventor： Geng Fu ,  Peter Michael Edic ,  Brian David Yanoff ,  Jianjun Guo ,  Vladimir A. Lobastov ,  Yannan Jin

IPC: A61B6/00 ,  A61B6/03

CPC classification number: A61B6/4241 ,  A61B6/032 ,  A61B6/4208 ,  A61B6/4233 ,  A61B6/4435 ,  A61B6/4441 ,  A61B6/461 ,  A61B6/467 ,  A61B6/5205 ,  A61B6/54

Abstract: Some embodiments are associated with an input signal comprising a first and a second photon event incident on a photon-counting semiconductor detector. A relatively slow charge collection shaping amplifier may receive the input signal and output an indication of a total amount of energy associated with the superposition of the first and second events. A relatively fast charge collection shaping amplifier may receive the input signal and output an indication that is used to allocate a first portion of the total amount of energy to the first event and a second portion of the total amount of energy to the second event.

公开(公告)号：US11557069B2

公开(公告)日：2023-01-17

申请号：US16222586

申请日：2018-12-17

Applicant: General Electric Company

Inventor： Robert F. Senzig ,  Ravikanth Avancha ,  Bijan Dorri ,  Sandeep Dutta ,  Steven J. Gray ,  Jiang Hsieh ,  John Irvin Jackson ,  Giridhar Jothiprasad ,  Paul Edgar Licato ,  Darin Robert Okerlund ,  Toshihiro Rifu ,  Saad Ahmed Sirohey ,  Basel Taha ,  Peter Michael Edic ,  Jerome Knoplioch ,  Rahul Bhotika

IPC: A61B5/00 ,  G06T11/00 ,  A61B6/03 ,  A61B6/00 ,  G06T7/00 ,  G16Z99/00

Abstract: A system and method for estimating vascular flow using CT imaging include a computer readable storage medium having stored thereon a computer program comprising instructions, which, when executed by a computer, cause the computer to acquire a first set of data comprising anatomical information of an imaging subject, the anatomical information comprises information of at least one vessel. The instructions further cause the computer to process the anatomical information to generate an image volume comprising the at least one vessel, generate hemodynamic information based on the image volume, and acquire a second set of data of the imaging subject. The computer is also caused to generate an image comprising the hemodynamic information in combination with a visualization based on the second set of data.

公开(公告)号：US20220071497A1

公开(公告)日：2022-03-10

申请号：US17422653

申请日：2020-01-16

Applicant: General Electric Company

Inventor： Prem Venugopal ,  Peter Michael Edic ,  Thomas Kwok-Fah Foo

IPC: A61B5/02 ,  A61B5/00 ,  G16H50/20 ,  G16H50/70 ,  G16H50/30 ,  G16H30/40 ,  G06T7/00

Abstract: The present disclosure relates to the use of prior images acquired of the patient and acoustic signature from a vascular region of interest to create a patient-specific model of sound propagation from the vascular region. This model is then used to monitor the progression of disease in the vascular region of interest, using subsequently-acquired acoustic signals. In an alternate embodiment, population-based images and/or population-based acoustic signatures are used to generate predictive data when a priori patient-specific imaging information is not available and this data is used to characterize or categorize at-risk patients suspected of coronary artery disease, but without prior cardiac events.

公开(公告)号：US11134907B2

公开(公告)日：2021-10-05

申请号：US16782584

申请日：2020-02-05

Applicant: General Electric Company

Inventor： Xue Rui ,  Mingye Wu ,  Yannan Jin ,  Peter Michael Edic ,  Bruno Kristiaan Bernard De Man

IPC: A61B6/00 ,  A61B6/03

Abstract: A signal processing method is disclosed, which includes detecting a total intensity of X-rays passing through an object comprising multiple materials; obtaining at least one set of basis information of basis material information of the multiple materials and basis component information of photon-electric absorption basis component and Compton scattering basis component of the object; estimating a scatter intensity component of the detected X-rays based on the at least one set of basis information and the detected total intensity; and obtaining an intensity estimate of primary X-rays incident on a detector based on the detected total intensity and the estimated scatter intensity component. An imaging system adopting the above signal processing method is also disclosed.

公开(公告)号：US10674986B2

公开(公告)日：2020-06-09

申请号：US15154360

申请日：2016-05-13

Applicant: General Electric Company

Inventor： Prem Venugopal ,  Jed Douglas Pack ,  Bruno Kristiaan Bernard De Man ,  Peter Michael Edic ,  Jiang Hsieh

IPC: A61B6/00 ,  A61B6/03

Abstract: The present approach provides a non-invasive methodology for estimation of coronary flow and/or fractional flow reserve. In certain implementations, various approaches for personalizing blood flow models of the coronary vasculature are described. The described personalization approaches involve patient-specific measurements and do not assume or rely on the resting coronary flow being proportional to myocardial mass. Consequently, there are fewer limitations in using these approaches to obtain coronary flow and/or fractional flow reserve estimates non-invasively.

公开(公告)号：US20200170599A1

公开(公告)日：2020-06-04

申请号：US16782584

申请日：2020-02-05

Applicant: General Electric Company

Inventor： Xue Rui ,  Mingye Wu ,  Yannan Jin ,  Peter Michael Edic ,  Bruno Kristiaan Bernard De Man

IPC: A61B6/00 ,  A61B6/03

Abstract: A signal processing method is disclosed, which includes detecting a total intensity of X-rays passing through an object comprising multiple materials; obtaining at least one set of basis information of basis material information of the multiple materials and basis component information of photon-electric absorption basis component and Compton scattering basis component of the object; estimating a scatter intensity component of the detected X-rays based on the at least one set of basis information and the detected total intensity; and obtaining an intensity estimate of primary X-rays incident on a detector based on the detected total intensity and the estimated scatter intensity component. An imaging system adopting the above signal processing method is also disclosed.

公开(公告)号：US20200160509A1

公开(公告)日：2020-05-21

申请号：US16192551

申请日：2018-11-15

Applicant: General Electric Company

Inventor： Jed Douglas Pack ,  Peter Michael Edic ,  Xin Wang ,  Xia Li ,  Prem Venugopal ,  James Vradenburg Miller

IPC: G06T7/00 ,  G06N3/08 ,  G16H50/20 ,  G16H30/40

Abstract: The present disclosure relates to training one or more neural networks for vascular vessel assessment using synthetic image data for which ground-truth data is known. In certain implementations, the synthetic image data may be based in part, or derived from, clinical image data for which ground-truth data is not known or available. Neural networks trained in this manner may be used to perform one or more of vessel segmentation, decalcification, Hounsfield unit scoring, and/or estimation of a hemodynamic parameter.