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公开(公告)号：US11235178B2
公开(公告)日：2022-02-01
申请号：US16121223
申请日：2018-09-04
Applicant: General Electric Company
Inventor： Christopher Michael Puleo , Yang Zhao , Kirk Dennis Wallace , Ying Fan , Jeffrey Michael Ashe , David Andrew Shoudy
Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.
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公开(公告)号：US20210068793A1
公开(公告)日：2021-03-11
申请号：US16567996
申请日：2019-09-11
Applicant: General Electric Company
Inventor： Asha Singanamalli , David Andrew Shoudy , Jeffrey Michael Ashe , Christopher Michael Puleo
Abstract: Embodiments of the present disclosure relate to techniques for neuromodulation delivery. Based on image data acquired from the subject, control parameters controlling energy application of neuromodulating energy may be dynamically changed during the course of the delivery to maintain desired characteristics of the neuromodulating energy. For example, the beam of the neuromodulating energy may be dynamically adjusted to account for movement of an organ during breathing. In another embodiment, a desired region of interest is identified within the subject based on a trained neural network and the acquired image data.
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公开(公告)号：US10357178B2
公开(公告)日：2019-07-23
申请号：US14970589
申请日：2015-12-16
Applicant: General Electric Company
Inventor： Gregory Boverman , David Michael Davenport , Jeffrey Michael Ashe , Bruce Courtney Campbell Amm
Abstract: A method includes applying a plurality of currents to a plurality of electrodes disposed on a surface surrounding an anatomical region in a subject. Further, the method includes measuring a plurality of voltages generated in response to the plurality of currents. The method also includes selecting a coarse-scale basis corresponding to a response function associated with the plurality of electrodes. Moreover, the method includes determining simultaneously an internal admittivity corresponding to the anatomical region and a contact impedance corresponding to the plurality of electrodes based on the plurality of voltages and the coarse-scale basis. The method also includes reconstructing the diagnostic image based on the internal admittivity.
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34.发明授权公开(公告)号：US09854994B2
公开(公告)日：2018-01-02
申请号：US14716522
申请日：2015-05-19
Applicant: General Electric Company
Inventor： Jeffrey Michael Ashe , Ting Yu , Yang Zhao
CPC classification number: A61B5/0816 , A61B5/113 , A61B5/7235 , A61B5/7278 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61B5/746
Abstract: A system and method include a plurality of sensors proximate a subject, wherein each sensor includes a plurality of antennas, and wherein each sensor operates on a plurality of frequency channels. The method includes receiving, at a respiration module, a signal associated with each antenna for each of the plurality of frequency channels; and calculating a respiration rate of the subject based on the received signal associated with each antenna for each of the plurality of frequency channels. Numerous other aspects are provided.
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公开(公告)号：US09147144B2
公开(公告)日：2015-09-29
申请号：US13630954
申请日：2012-09-28
Applicant: General Electric Company
Inventor： Radislav Alexandrovich Potyrailo , Jeffrey Michael Ashe , Sm Shajed Hasan , Naresh Kesavan Rao , Krishnakumar Sundaresan
IPC: G01N27/00 , G06K19/07 , G06K19/077
CPC classification number: G06K19/0717 , G06K19/0723 , G06K19/07749
Abstract: A method for multivariable measurements using a single-chip impedance analyzer includes providing a sensor, exposing the sensor to an environmental parameter, determining a complex impedance of the sensor over a measured spectral frequency range of the sensor, and monitoring at least three spectral parameters of the sensor.
Abstract translation: 使用单芯片阻抗分析仪进行多变量测量的方法包括提供传感器，将传感器暴露于环境参数，在传感器的测量光谱频率范围内确定传感器的复阻抗，以及监测至少三个光谱参数 传感器。
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Patent Agency Ranking
公开(公告)号：US11786760B2
公开(公告)日：2023-10-17
申请号：US16709717
申请日：2019-12-10
Applicant: General Electric Company
Inventor： John Frederick Graf , Christopher Michael Puleo , Jeffrey Michael Ashe , Victoria Eugenia Cotero , David Andrew Shoudy
IPC: A61N7/00
CPC classification number: A61N7/00 , A61N2007/0026 , A61N2007/0052 , A61N2007/0086
Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.
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公开(公告)号：US20220362587A1
公开(公告)日：2022-11-17
申请号：US17864212
申请日：2022-07-13
Applicant: General Electric Company
Inventor： Christopher Michael Puleo , Victoria Eugenia Cotero , Jeffrey Michael Ashe , John Frederick Graf
Abstract: Embodiments of the present disclosure relate to techniques for inducing physiological perturbations in a subject via neuromodulation, e.g., peripheral neuromodulation of a region of interest of an organ. The nature and degree of the perturbations may be related to the subject's clinical condition. Accordingly, an assessment of one or more characteristics of the perturbations may be used to determine a clinical condition of the subject.
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公开(公告)号：US20220233886A1
公开(公告)日：2022-07-28
申请号：US17161022
申请日：2021-01-28
Applicant: General Electric Company
Inventor： David Andrew Shoudy , Jeffrey Michael Ashe , Warren Lee , Ying Fan
IPC: A61N7/00
Abstract: The present discussion relates to the delivery of ultrasonic therapy energy to a target region in conjunction with a clear path determination that may assess one or more of: (1) presence of non-soft tissue regions within the therapy beam path (e.g., bone or bone-like structures, gas-filled cavities, and so forth), (2) partial “lift-off” of the probe head; or (3) sufficiency of acoustic coupling. Upon determination or confirmation of at least a partial clear path with respect to some or all of these factors, the therapy beam may be delivered to the target region.
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公开(公告)号：US20210299449A1
公开(公告)日：2021-09-30
申请号：US17342186
申请日：2021-06-08
Applicant: General Electric Company
Inventor： Christopher Michael Puleo , Jeffrey Michael Ashe , Victoria Eugenia Cotero , Michael Ernest Marino
Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of lymphatic tissue that include applying one or more energy pulses to a neuron of a subject, e.g., via an electrode positioned to deliver sufficient energy to the neuron, to modulate immune function. For example, an adaptive immune reflex of a subject may be modulated via neuromodulation
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公开(公告)号：US10357177B2
公开(公告)日：2019-07-23
申请号：US14105203
申请日：2013-12-13
Applicant: General Electric Company
Inventor： Gregory Boverman , Jeffrey Michael Ashe , Bruce Courtney Campbell Amm
Abstract: A method and system for performing electrical impedance imaging of a subject of interest using a plurality of electrodes is provided. The method includes applying one or more determined current patterns to one or more electrodes of the plurality of electrodes. Further, the method includes determining a resultant voltage at at least one electrode of the one or more electrodes in response to the one or more determined current patterns. Moreover, the method includes estimating a change in a contact impedance for the at least one electrode of the one or more electrodes. Additionally, the method includes calculating a compensated voltage for the at least one electrode based on an estimated change in a corresponding contact impedance of the at least one electrode.
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