Abstract:
Methods and compositions for prophylaxis and/or treatment of diseases of the eye of a patient resulting angiogenesis in the eye using antagonists of the integrin receptors αv β3 and/or αv β5. The compositions can be nanoparticles and are administered to the eye by injection into the sclera of the eye.
Abstract:
Methods and compositions for prophylaxis and/or treatment of diseases of the eye of a patient resulting angiogenesis in the eye using antagonists of the integrin receptors αvβ3 and/or αvβ5. The compositions can be nanoparticles and are administered to the eye by injection into the sclera of the eye.
Abstract:
A system and method for frequent and accurate measuring of flat sheet thickness on a process line is disclosed. The results of the monitoring process of the present invention may be used to adjust the production process to better remain within predetermined tolerances. Data collection, data analysis, and process control are accomplished using a plurality of software applications in communication with various devices and equipment that support these functions of the present invention. A source/dectector unit collects data during the production process. The data is transmitted, manipulated, analyzed, and compared for conformance to tolerances and error signal output is transmitted to a process control system used to control the production process. If the sheet product is outside a specified tolerance range, an operator may also be notified so that corrective actions can be taken. Software applications may be used by an operator to perform setup and configuration operations.
Abstract:
A system and method for managing implementation of policies in an information technologies system receives at least one policy function, at least one refinement template and at least one available policy function from the at least one memory, receives a policy input indicating a high-level policy for the IT system where the policy input is compliant with the at least one policy function and is received in a format that is not machine-enforceable at an enforcement entity of the IT system, based on the received policy input, automatically or semi-automatically generates a machine-enforceable rule and/or configuration by filling the at least one refinement template, where the machine-enforceable rule and/or configuration includes the at least one available policy function and being compliant with the received policy input, and distributes the machine-enforceable rule and/or configuration to the at least one memory of the IT system or another at least one memory to thereby enable implementation of the policies.
Abstract:
A method of managing supply chain risks having a supply chain risk analysis implementation, includes loading from a data storage or a memory, supply chain data for a supply chain which indicates information about the supply chain; mapping the supply chain data to a consistent input model; automatically analyzing, by an analytics module implemented on a processor, the input model to detect supply chain anomalies indicating the supply chain risks; producing an analysis results output of the analyzed input model; and outputting the analysis results output of the detected supply chain anomalies to the memory, the data storage, a display, or a message. A supply chain risk analysis system includes the processor, the data storage or the memory that stores the supply chain data for the supply chain which indicates information about the supply chain. The processor is configured to perform the processes.
Abstract:
A method of managing supply chain risks having a supply chain risk analysis implementation, includes loading from a data storage or a memory, supply chain data for a supply chain which indicates information about the supply chain; mapping the supply chain data to a consistent input model; automatically analyzing, by an analytics module implemented on a processor, the input model to detect supply chain anomalies indicating the supply chain risks; producing an analysis results output of the analyzed input model; and outputting the analysis results output of the detected supply chain anomalies to the memory, the data storage, a display, or a message. A supply chain risk analysis system includes the processor, the data storage or the memory that stores the supply chain data for the supply chain which indicates information about the supply chain. The processor is configured to perform the processes.
Abstract:
A policy management system includes a policy management device that is configured to manage a policy input and/or a template and/or a functional model, a policy enforced device that is directly or indirectly connected to the policy management device via a network and that is configured such that at least a part of the functional model managed by the policy management device reflects the functional features/behaviors of the policy enforced device, a policy enforcement device that is configured to execute policy enforcement on the policy enforced device, and a policy decision device that is configured to receive machine-enforceable rule and/or configuration from the policy management device. The policy enforcement device, when a policy relevant event occurs, instructs the policy decision device to determine the result of the condition of the transmitted machine-enforceable rule and/or configuration for implementing the policy input for the policy enforced device, thereby modifying an operation of the policy enforced device or the policy enforcement device to execute the action.
Abstract:
The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.
Abstract:
The invention relates to a laying device which is used to lay wire windings on transponder units, wherein the wire is guided in an axial manner in the laying device, a contacting device is used place the wires in contact with an automatic thermal clamping arrangement, an advancing system is used to advance machining devices by means of a piezo-leg-motor, a production system is used to produce transponder units in a console structural manner. The invention also relates to a method for the production of transponder units with horizontal ultrasonic introduction and a transponder unit wherein the wire ends engage directly on the ends of the connection surfaces of the chip.
Abstract:
Methods for the treatment of a disease of the eye of a patient comprising injecting into the vitreous body of the eye a composition comprising a therapeutically effective amount of an αvβ3 and/or αvβ5 inhibitor sufficient to inhibit angiogenesis and inhibit neovascularization in the treated eye. The αvβ3 and/or αvβ5 inhibitor being a compound of formula II: as defined herein or a physiologically acceptable salt thereof.