公开(公告)号：US11120312B2

公开(公告)日：2021-09-14

申请号：US16203445

申请日：2018-11-28

Applicant: Elucid Bioimaging Inc.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A. Moulton ,  Mark A. Buckler ,  Vladimir Valtchinov ,  David S. Paik

IPC: G06K9/00 ,  G06K9/62 ,  A61B6/03 ,  A61B6/00

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US11087460B2

公开(公告)日：2021-08-10

申请号：US16206454

申请日：2018-11-30

Applicant: Elucid Bioimaging Inc.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A. Moulton ,  Mark A. Buckler ,  Vladimir Valtchinov ,  David S. Paik

IPC: G06K9/00 ,  G06T7/00 ,  G06T7/11 ,  G06N20/00 ,  G06N3/08 ,  G06K9/32 ,  G06T5/00 ,  G06K9/62 ,  G06T3/00

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US11071501B2

公开(公告)日：2021-07-27

申请号：US16203440

申请日：2018-11-28

Applicant: Elucid Bioimaging Inc.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A. Moulton ,  Mark A. Buckler ,  Vladimir Valtchinov ,  David S. Paik

IPC: G06K9/00 ,  A61B5/00 ,  G06T5/00 ,  G06T5/20 ,  G06T11/00 ,  G06T11/60 ,  A61B6/00 ,  G16H30/40 ,  G06N3/08 ,  G06T7/00 ,  A61B5/103 ,  G16H50/20 ,  G16H50/50 ,  G16H10/60 ,  A61B5/02 ,  A61B5/055 ,  A61B8/08 ,  A61B5/107 ,  A61B6/03 ,  A61B5/145

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US10755810B2

公开(公告)日：2020-08-25

申请号：US15237249

申请日：2016-08-15

Applicant: ELUCID BIOIMAGING INC.

Inventor： Andrew J. Buckler ,  Keith A. Moulton ,  Mary Buckler ,  Larry Martell ,  David S. Paik ,  Xiaonan Ma ,  Samantha St. Pierre

IPC: G16H30/40 ,  G16H10/60 ,  G16H50/20 ,  G06F21/62

Abstract: Methods and systems are disclosed for structuring and using information pertinent to in vivo biomarkers, specifically quantitative imaging biomarkers, using semantic web technology for personalized medicine and discovery science. It supports the development and application of statistical evidence at a level of granularity and sophistication more closely tied to the complexity of the disease itself and its underlying biology, including technology linking multiple biological scales, than has previously been eedisclosed. It provides data and computational services to analyze quantitative imaging and non-imaging data, coupled with multi-scale modeling to elucidate pre-symptomatic and clinical disease processes. It may be used to assess technical or analytical performance for its own sake and/or to further annotate the quantitative analysis. It supports statistical hypothesis testing to determine and present analytical performance, determine the clinical relevance and establish to what extent a biomarker is causally rather than coincidentally related in clinical contexts of use.

公开(公告)号：US20190074082A1

公开(公告)日：2019-03-07

申请号：US16102042

申请日：2018-08-13

Applicant: Elucid Bioimaging Inc.

Inventor： Mary E. Buckler ,  Xiaonan Ma ,  Lawrence Martell ,  Andrew J. Buckler

IPC: G16H30/20 ,  G06T7/00 ,  G06F17/30 ,  G06F17/27

Abstract: Advanced reporting systems based on ontology development for quantitative imaging biomarkers, information modeling to integrate heterogeneous data types relevant to quantitative medical analysis, and a knowledge representation framework for their statistical validation.

公开(公告)号：US12159406B2

公开(公告)日：2024-12-03

申请号：US18545542

申请日：2023-12-19

Applicant: ELUCID BIOIMAGING INC.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A Moulton ,  David S. Paik

IPC: G06T7/00 ,  G06F18/211 ,  G06F18/214 ,  G06F18/24 ,  G06N3/08 ,  G06N20/00 ,  G06T3/00 ,  G06T5/73 ,  G06T7/11 ,  G06V10/25 ,  G06V10/764 ,  G06V20/69

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US12141975B2

公开(公告)日：2024-11-12

申请号：US18415137

申请日：2024-01-17

Applicant: ELUCID BIOIMAGING INC.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A. Moulton ,  David S. Paik

IPC: G06T7/00 ,  G06F18/211 ,  G06F18/214 ,  G06F18/24 ,  G06N3/08 ,  G06N20/00 ,  G06T3/00 ,  G06T5/73 ,  G06T7/11 ,  G06V10/25 ,  G06V10/764 ,  G06V20/69

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US12136214B2

公开(公告)日：2024-11-05

申请号：US18415125

申请日：2024-01-17

Applicant: ELUCID BIOIMAGING INC.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A. Moulton ,  David S. Paik

IPC: G06T7/00 ,  G06F18/211 ,  G06F18/214 ,  G06F18/24 ,  G06N3/08 ,  G06N20/00 ,  G06T3/00 ,  G06T5/73 ,  G06T7/11 ,  G06V10/25 ,  G06V10/764 ,  G06V20/69

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US12131471B2

公开(公告)日：2024-10-29

申请号：US18504795

申请日：2023-11-08

Applicant: ELUCID BIOIMAGING INC.

Inventor： Andrew J. Buckler ,  Kjell Johnson ,  Xiaonan Ma ,  Keith A. Moulton ,  David S. Paik

IPC: G06T7/00 ,  G06F18/211 ,  G06F18/214 ,  G06F18/24 ,  G06N3/08 ,  G06N20/00 ,  G06T3/00 ,  G06T5/73 ,  G06T7/11 ,  G06V10/25 ,  G06V10/764 ,  G06V20/69

CPC classification number: G06T7/0012 ,  G06F18/211 ,  G06F18/2148 ,  G06F18/24 ,  G06N3/08 ,  G06N20/00 ,  G06T3/00 ,  G06T5/73 ,  G06T7/11 ,  G06V10/25 ,  G06V10/764 ,  G06V20/69 ,  G06T2207/10048 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30096 ,  G06T2207/30104

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

公开(公告)号：US12125572B2

公开(公告)日：2024-10-22

申请号：US18232231

申请日：2023-08-09

Applicant: Elucid Bioimaging Inc.

Inventor： Andrew J. Buckler ,  Ulf Hedin ,  Ljubica Matic ,  Matthew Phillips

IPC: G16H20/10 ,  G16B5/00

CPC classification number: G16H20/10 ,  G16B5/00

Abstract: Provided herein are methods and systems for making patient-specific therapy recommendations of an anti-inflammatory therapy for patients with known or suspected cardiovascular disease, such as atherosclerosis.